A5065162967- Skin Protection and Aging
- Multiple Sclerosis Research Studies
- Vitamin D Research Studies
- T-cell and B-cell Immunology
- Allergic Rhinitis and Sensitization
- Nutritional Studies and Diet
- Viral Infections and Immunology Research
- Acne and Rosacea Treatments and Effects
- Cutaneous Melanoma Detection and Management
- Immunotherapy and Immune Responses
- Dermatology and Skin Diseases
- Chromosomal and Genetic Variations
- Asthma and respiratory diseases
- Thyroid Disorders and Treatments
- Blood properties and coagulation
- Animal testing and alternatives
- Peripheral Neuropathies and Disorders
- Urban Green Space and Health
- interferon and immune responses
- Climate Change and Health Impacts
- Adipose Tissue and Metabolism
- Indoor Air Quality and Microbial Exposure
- Systemic Lupus Erythematosus Research
- Effects and risks of endocrine disrupting chemicals
- Galectins and Cancer Biology
Bispebjerg Hospital
2012-2021
University of Copenhagen
2012-2021
Copenhagen University Hospital
2001-2019
Rigshospitalet
2001-2008
Danish Multiple Sclerosis Center
2006-2008
Summary Several studies indicate genetic involvement of Th2 cytokines in allergic diseases. Interleukin (IL)‐13 has been mapped to the cytokine cluster on chromosome 5q31–33, which associated with atopic conditions. Recently, an association was reported between T allele a promoter polymorphism IL‐13 gene (C exchange) at position −1055 and asthma population study Netherlands. This observation apparently confirmed case–control using probands spouses from Dutch family study, but that occur...
IMPORTANCE UV radiation (UVR) exposure is the primary environmental risk factor for developing cutaneous malignant melanoma (CMM). OBJECTIVE To measure changes in sun behavior from first until third summer after diagnosis of CMM using matched controls as a reference. DESIGN, SETTING, AND PARTICIPANTS Three-year follow-up, observational, case-control study performed May 7 to September 22, 2009, April 17 15, 2010, and 6 July 31, 2011, at university hospital Denmark 21 patients with by sex,...
Treatment with interferon-beta (IFN-beta) induces the expression of hundreds genes in blood mononuclear cells, and several has been proposed as a marker effect treatment IFN-beta. However, to date no molecules have identified that are stably induced by We use DNA microarrays study gene 10 multiple sclerosis (MS) patients who began de novo After first injection IFN-beta, 74 out 3428 changed at least two-fold statistically significantly (after Bonferroni correction). In contrast, we observed...
Journal Article Sun behaviour after cutaneous malignant melanoma: a study based on ultraviolet radiation measurements and sun diary data Get access L.W. Idorn, Idorn Dermatological Research Department D92, Bispebjerg Hospital, University of Copenhagen, Copenhagen DK‐2400, Denmark Luise Winkel Idorn. E‐mail: luise.idorn@gmail.com Search for other works by this author on: Oxford Academic Google Scholar P. Datta, Datta J. Heydenreich, Heydenreich P.A. Philipsen, Philipsen H.C. Wulf British...
Investigation of coaffected sib pairs is one method to determine the genetic influence on clinical presentation many complex diseases, such as multiple sclerosis (MS). concordance in may be a prerequisite identify genes that modify outcome. The aim this study was investigate possible selected demographic and variables among familial Scandinavian MS cases.We identified 136 Caucasian families with from Denmark, Norway Sweden. Cohen's kappa coefficient intraclass correlation were used assess...
Abstract Background The inter‐individual variation in 25(OH)D 3 increase (Δ25(OH)D ) after vitamin D supplementation was determined and compared with the UVB irradiation response. Methods Nineteen Danish participants received 85 μg (cholecalciferol) daily for nine weeks regular serum measurements. These had three years earlier taken part a 9‐week controlled study. Δ25(OH)D not confounded by ambient UVB, BMI or ethnicity. Results 53 nmol L −1 almost identical to (52 UVB. ranged from 17 91...
In this study, the results from three Nordic linkage disequilibrium screens in multiple sclerosis (MS) were investigated, a new sample set of 314 MS trios Denmark, Norway, Sweden and Iceland. Among 30 non-HLA two HLA microsatellite markers individually genotyped, eight displayed distorted transmission with uncorrected P-value <0.05, ranked order: D6S2443 (6p21.32, class II) (P corrected =0.01), D2S2201 (2p24), D19S552 (19q13), D3S3584 (3q21), D17S975 (17q11), D1S2627 (1p22), D6S273...