Dalapathi Gugulothu

ORCID: 0000-0001-5615-201X
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About
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Research Areas
  • Advanced Drug Delivery Systems
  • RNA Interference and Gene Delivery
  • Skin Protection and Aging
  • Histone Deacetylase Inhibitors Research
  • Polysaccharides Composition and Applications
  • Moringa oleifera research and applications
  • Nanoparticle-Based Drug Delivery
  • Protein purification and stability
  • Advancements in Transdermal Drug Delivery
  • Nanoparticles: synthesis and applications
  • Diverse Scientific Research Studies
  • HIV Research and Treatment
  • Phytochemicals and Medicinal Plants
  • Nanoplatforms for cancer theranostics
  • Disaster Response and Management
  • Cancer, Hypoxia, and Metabolism
  • Genetics and Neurodevelopmental Disorders
  • Viral Infections and Outbreaks Research
  • COVID-19 epidemiological studies
  • Immunotherapy and Immune Responses
  • Autophagy in Disease and Therapy
  • Polysaccharides and Plant Cell Walls
  • melanin and skin pigmentation
  • Epigenetics and DNA Methylation
  • Mitochondrial Function and Pathology

Delhi Pharmaceutical Science and Research University
2023-2025

Background: The metal oxide nanoparticles possess unique properties such as biological compatibility, superior reactivity, and capacity to develop reactive oxygen species, due this they have drawn significant interest in cancer treatment. various MONPs cerium oxide, Copper Iron Titanium dioxide, Zinc been investigated for several types of cancers including brain, breast, cervical, colon, leukemia, liver, lung, melanoma, ovarian, prostate cancers. However, traditional physiochemical synthetic...

10.2174/0113816128329342241120105041 article EN Current Pharmaceutical Design 2025-01-07

Epigenetics mechanisms play a crucial role in regulating gene expression and cellular function the development progression of neurological disorders. Emerging evidence suggests that dysregulation these epigenetic processes contributes significantly to pathogenesis various disorders, including Alzheimer's disease, Parkinson's epilepsy. Epigenetic mechanisms, DNA methylation, histone modification, non-coding RNAs, impact neural plasticity. The use modulators, methyltransferase deacetylase...

10.2174/0113816128330087241030093112 article EN Current Pharmaceutical Design 2025-02-11

Abstract: Skin ageing is influenced by intrinsic factors such as genetics and hormones, well extrinsic like environmental exposure, ultraviolet (UV) radiation, diet. These lead to biochemical, biological, structural changes in the skin. Plant-derived compounds with antioxidant anti-inflammatory properties have emerged potential anti-ageing agents. This comprehensive review, spanning data from 1997 2024, explores role of nutraceuticals skin anti-ageing. The research were drawn Google, PubMed,...

10.2174/0113816128336661250218080928 article EN Current Pharmaceutical Design 2025-03-03

Abstract Entacapone is utilized as an adjunct to levodopa therapy for the treatment of Parkinson's syndrome. According Biopharmaceutics Classification System, it classified a class IV drug. The solubility substance can be enhanced by utilizing nanoemulsion, which also effectively traverse blood-brain barrier owing its nanoscale dimensions. formulation various proportions Capmul Medium Chain Mono and Diglycerides oil phase, Pluronic F127, Phospholipin 90 hydrophilic lipophilic surfactants....

10.21203/rs.3.rs-4081418/v1 preprint EN cc-by Research Square (Research Square) 2024-03-14

Abstract: The Marburg virus (MARV), which belongs to the family Filoviridae, is cause of disease (MVD), a that can be fatal. Laboratories employees and Frankfurt cities Germany, Belgrade city Yugoslavia (now Serbia), contracted an infection caused by hitherto unidentified infectious pathogen in August 1967. According World Health Organization (WHO), MARV one most im-portant issues world. With case fatality rate ranging from 24.0 88.0%, very dangerous, underscoring need for public awareness....

10.2174/0122113525341920241015041123 article EN Anti-Infective Agents 2024-11-11
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