A5103250751- Advanced Fiber Optic Sensors
- Machine Learning in Bioinformatics
- Photonic and Optical Devices
- Genomics and Phylogenetic Studies
- Advanced Fiber Laser Technologies
- Optical Coherence Tomography Applications
- RNA and protein synthesis mechanisms
- Gas Sensing Nanomaterials and Sensors
- Luminescence and Fluorescent Materials
- Photodynamic Therapy Research Studies
- Photonic Crystal and Fiber Optics
- Nanoplatforms for cancer theranostics
- Nanowire Synthesis and Applications
- vaccines and immunoinformatics approaches
- Angiogenesis and VEGF in Cancer
- Monoclonal and Polyclonal Antibodies Research
- Optical Systems and Laser Technology
- Computational Drug Discovery Methods
- Fractal and DNA sequence analysis
- Data Management and Algorithms
- High voltage insulation and dielectric phenomena
- Data Mining Algorithms and Applications
- Laser Material Processing Techniques
- Spectroscopy Techniques in Biomedical and Chemical Research
- Receptor Mechanisms and Signaling
Shenzhen University
2016-2024
Peng Cheng Laboratory
2024
Cancer is a serious health issue worldwide. Traditional treatment methods focus on killing cancer cells by using anticancer drugs or radiation therapy, but the cost of these quite high, and in addition there are side effects. With discovery peptides, great progress has been made treatment. For purpose prompting application peptides treatment, it necessary to use computational identify (ACPs). In this paper, we propose sequence-based model for identifying ACPs (SAP). our proposed SAP, peptide...
Alzheimer’s disease (AD) is considered to one of 10 key diseases leading death in humans. AD the main cause brain degeneration, and will lead dementia. It beneficial for affected patients be diagnosed with at an early stage so that efforts manage patient can begin as soon possible. Most existing protocols diagnose by way magnetic resonance imaging (MRI). However, because size images produced large, techniques employ MRI technology are expensive time-consuming perform. With this mind, current...
Antioxidant proteins can be beneficial in disease prevention. More attention has been paid to the functionality of antioxidant proteins. Therefore, identifying is important for study. In our work, we propose a computational method, called SeqSVM, predicting based on their primary sequence features. The features are removed reduce redundancy by max relevance distance method. Finally, identified support vector machine (SVM). experimental results demonstrated that method performs better than...
In this paper, a computational method based on machine learning technique for identifying Alzheimer's disease genes is proposed. Compared with most existing methods, methods predict by using structural magnetic resonance imaging (MRI) technique. Most have attained acceptable results, but the cost expensive and time consuming. Thus, we proposed Alzheimer use of sequence information proteins, classify feature vectors random forest. method, gene protein extracted adaptive k-skip-n-gram...
Abstract One‐for‐all phototheranostics based on a single molecule is recognized as convenient approach for cancer treatment, whose efficacy relies precise lesion localization through multimodal imaging, coupled with the efficient exertion of phototherapy. To unleash full potential phototheranostics, advancement in both phototheranostic agents and light delivery methods essential. Herein, an integrated strategy combining versatile featuring aggregation‐induced emission, namely tBuTTBD,...
A novel probe-type FPI-based fiber optic hydrogen sensor with a graphene–Au–Pd sandwich structure film and FBG is proposed experimentally demonstrated in this study.
Blood glucose concentration is important for metabolic homeostasis in humans and animals. Many diabetic patients need to detect blood daily which burdens community hospitals family healthcare. Optical fiber sensors are widely used biomedical detection because of their compact structure, fast response, high sensitivity, low cost, ease operation. In this work, we constructed a Fabry-Perot (FP) cavity biosensor the serum. The femtosecond laser micromachining was applied fabricate FP by printing...
We propose an ultrasensitive optofluidic detection method based on a hybrid-waveguide coupler for the discrimination of edible oils from gutter oils.
Abstract Glioblastoma (GBM) is one of the most lethal human malignancies. The current standard‐of‐care highly invasive with strong toxic side effects, leading to poor prognosis and high mortality. As a safe effective clinical approach, photodynamic therapy (PDT) has emerged as suitable option for GBM. Nevertheless, its implementation significantly impeded by limits light penetration depth firm reliance on oxygen. To overcome these challenges, herein, promising strategy that harnesses...
The demand for non-invasive, real-time health monitoring has driven advancements in wearable sensors tracking biomarkers sweat. Ammonium ions (NH4+) sweat serve as indicators of metabolic function, muscle fatigue, and kidney health. Although current ion-selective all-solid-state printed based on nanocomposites typically exhibit good sensitivity (~50 mV/log [NH4+]), low detection limits (LOD ranging from 10−6 to 10−7 M), wide linearity ranges (from 10−5 10−1 few have reported the stability...
The temporal response of conventional ZnO nanowire-based photodetectors suffers from the influence carrier mobility and high electrical resistance. As a result, these devices can be prohibitively slow for some applications, generally with time on order 1 second. This study presents novel microfiber coupler structure all-optical photodetection without demand photocurrent generation. In this design, two waveguides are directly adsorbed by van der Waals forces or electrostatic forces. Compared...
Background: Cell lytic enzyme is a kind of highly evolved protein, which can destroy the cell structure and kill bacteria. Compared with antibiotics, will not cause serious problem drug resistance pathogenic Thus, study wall enzymes aims at finding an efficient way for curing bacteria infectious. using becomes more serious. Therefore, it good choice bacterial infections by enzymes. includes endolysin autolysin difference between them purpose break wall. The identification type meaningful...
We demonstrate a silica diaphragm-based fiber tip Fabry-Perot interferometer (FPI) for high-pressure (40 MPa) sensing. By using polishing technique, the thickness of diaphragm could be precisely controlled and pressure sensitivity fabricated FPI sensor was enhanced significantly by reducing thickness; however, relationship between is not linear. A high -1.436 nm/MPa linearity 0.99124 in hydraulic range 0 to 40 MPa were demonstrated with 4.63 μm. The achieved about one order magnitude higher...
Tumor cells invade normal surrounding tissues through continuous division. In this study, we hypothesized that cell cycle regulation changes the immune efficacy of ovarian cancer. To investigate hypothesis, a Förster resonance energy transfer (FRET) sensor was constructed to characterize activity in real time. Cell shrinkage caused by apoptosis induces aggregation proteins on membrane, leading variations fluorescence lifetime FRET sensors. Moreover, tracked across various cycles following...
An ultra-thin spiral diffractive lens (SDL) was fabricated by using focused ion beam milling on a fiber end-facet coated with 100 nm thick Au film. Focusing vortex beams (FVBs) were successfully excited the SDLs due to coherent superposition of diffracted waves and their azimuth dependence phase accumulated from aperture axis. The polarization characteristics FVBs experimentally investigated. Results show that input various states converted FVBs, whose same as those beams. Furthermore, focal...
Migration of lab-on-chip configurations into the optical fiber platform opens revolutionary prospect lab-in-fiber systems on basis an efficient transport highway for multifunctional sensing. In this paper, three-dimensional microfluidic channels patterning inside by femtosecond laser ablation, assisted splicing and selective chemical etching will be introduced in terms machining mechanism accuracy. these approaches, we have successfully achieved phase-shifted FBG sensor based in-grating...
Get PDF Email Share with Facebook Tweet This Post on reddit LinkedIn Add to CiteULike Mendeley BibSonomy Citation Copy Text Y. Wang, Z. Peng, C. Liao, and "Thermal response time measurement of photonic crystal fiber device based anti-resonant reflecting guidance," in Asia Pacific Optical Sensors Conference, OSA Technical Digest (online) (Optica Publishing Group, 2016), paper Th4A.14. Export BibTex Endnote (RIS) HTML Plain alert Save article
Microsized endoscopy is increasingly demanded in medical clinical diagnosis for imaging small blood vessels or delicate organs. In this paper, we propose a 3D printed side-viewing microlens on fiber tip by using the femtosecond laser two-photon polymerization (TPP) method optical coherence tomography (OCT) applications. The only 210 μm width and 270 height, its measured lateral resolution around 9.4 air. It demonstrated that proposed can easily profile depth resolved inner structure of...
Semiconductor-based photodetectors have received wide attention. Traditional are based on electrical test methods, which inevitably disturbed by dark current noise. In order to overcome this problem, paper proposes an all-optical photodetection scheme a microfiber/SiC-nanowire directional coupling structure, directly utilizes the refractive index change of SiC nanowire caused photogenerated carriers instead photocurrent. The device is fabricated transferring single microfiber with diameter...