Luis Garcia‐Gancedo

ORCID: 0000-0001-5631-1711
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About
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Research Areas
  • Acoustic Wave Resonator Technologies
  • Mechanical and Optical Resonators
  • Rheumatoid Arthritis Research and Therapies
  • Advanced Sensor and Energy Harvesting Materials
  • Ultrasound Imaging and Elastography
  • Autoimmune and Inflammatory Disorders Research
  • Analytical Chemistry and Sensors
  • Advanced MEMS and NEMS Technologies
  • Ultrasonics and Acoustic Wave Propagation
  • ZnO doping and properties
  • Microfluidic and Bio-sensing Technologies
  • Amyotrophic Lateral Sclerosis Research
  • Advanced biosensing and bioanalysis techniques
  • Ultrasound and Hyperthermia Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Electrochemical sensors and biosensors
  • Magnetic Properties and Applications
  • Social Media in Health Education
  • Electrochemical Analysis and Applications
  • Diamond and Carbon-based Materials Research
  • Metal and Thin Film Mechanics
  • Parkinson's Disease Mechanisms and Treatments
  • Systemic Lupus Erythematosus Research
  • Neurogenetic and Muscular Disorders Research
  • Metallic Glasses and Amorphous Alloys

Health Economics and Outcomes Research (United Kingdom)
2022-2024

Age UK
2020-2021

GlaxoSmithKline (United Kingdom)
2018-2020

University of Hertfordshire
2020

University of Cambridge
2010-2016

Bridge University
2013

University of Birmingham
2007-2012

University of Dundee
2012

Tritech Group (United Kingdom)
2008

University of Brighton
2006-2007

Thin-film electronics in its myriad forms has underpinned much of the technological innovation fields displays, sensors, and energy conversion over past four decades. This technology also basis flexible electronics. Here we review current status attempt to predict future promise these pervading technologies healthcare, environmental monitoring, displays human-machine interactivity, conversion, management storage, communication wireless networks.

10.1109/jproc.2012.2190168 article EN other-oa Proceedings of the IEEE 2012-05-01

Digital measures of health status captured during daily life could greatly augment current in-clinic assessments for rheumatoid arthritis (RA), to enable better assessment disease progression and impact. This work presents results from weaRAble-PRO, a 14-day observational study, which aimed investigate how digital technologies (DHT), such as smartphones wearables, patient reported outcomes (PRO) determine RA severity in study 30 moderate-to-severe patients, compared matched healthy controls...

10.1038/s41746-024-01013-y article EN cc-by npj Digital Medicine 2024-02-12

Using smartphones to enroll, obtain consent, and gather self-reported data from patients has the potential enhance our understanding of disease burden quantify physiological impact in real world. It may also be possible harness integral smartphone sensors facilitate remote collection clinically relevant data.We conducted Patient Rheumatoid Arthritis Data From Real World (PARADE) observational study using a customized ResearchKit app with bring-your-own-device approach. Our objective was...

10.2196/mhealth.9656 article EN cc-by JMIR mhealth and uhealth 2018-07-10

Antibody orientation and its antigen binding efficiency at interface are of particular interest in many immunoassays biosensor applications. In this paper, spectroscopic ellipsometry (SE), neutron reflection (NR), dual polarization interferometry (DPI) have been used to investigate interfacial assembly the antibody [mouse monoclonal anti-human prostate-specific (anti-hPSA)] silicon oxide/water subsequent binding. It was found that mass density adsorbed increased with solution concentration...

10.1021/la201245q article EN Langmuir 2011-05-25

Surface acoustic wave (SAW) devices with 64 μm wavelength were fabricated on a zinc oxide (ZnO) film deposited top of an ultra-smooth nanocrystalline diamond (UNCD) layer. The smooth surface the UNCD allowed growth ZnO excellent c-axis orientation and low roughness, suitable for SAW fabrication, could restrain from significantly dissipating into substrate. frequency response was characterized Rayleigh mode observed at ∼65.4 MHz. This utilised to demonstrate that ZnO/UNCD device can be...

10.1063/1.3699974 article EN Biomicrofluidics 2012-04-03

Objective symptom monitoring of patients with Amyotrophic Lateral Sclerosis (ALS) has the potential to provide an important source information evaluate impact disease on aspects real-world functional capacity and activities daily living in home setting, providing useful objective outcome measures for clinical trials.This study aimed investigate feasibility a novel digital platform remote data collection multiple symptoms-physical activity, heart rate variability (HRV), speech...

10.2196/13433 article EN cc-by JMIR mhealth and uhealth 2019-09-26

Measures of physical activity patterns that may characterize rheumatoid arthritis status were investigated, using actigraphy data from a large, prospective database study (UK Biobank). Population characterization identified 1080 individuals with who participated in accelerometer-measured collection and met the eligibility criteria; these subsequently matched 2160 non-rheumatoid controls. Raw pre-processed to interpretable acceleration magnitude general signal-based features used derive...

10.1371/journal.pone.0319908 article EN cc-by PLoS ONE 2025-03-26

Abstract BACKGROUND: Carbon nanotube (CNT) fiber directly spun from an aerogel has a unique, well‐aligned nanostructure (nano‐pore and nano‐brush), thus provides high electro‐catalytic activity strong interaction with glucose oxidase enzyme. It shows great potential as microelectrode for electrochemical biosensors. RESULTS: Cyclic voltammogram results indicate that post‐synthesis treatments have influence on the electrocatalytic of CNT fibers. Raman spectroscopy electrical conductivity tests...

10.1002/jctb.2708 article EN Journal of Chemical Technology & Biotechnology 2011-08-19

The specific recognition between monoclonal antibody (anti-human prostate-specific antigen, anti-hPSA) and its antigen (human hPSA) has promising applications in prostate cancer diagnostics other biosensor applications. However, because of steric constraints associated with interfacial packing molecular orientations, the binding efficiency is often very low. In this study, spectroscopic ellipsometry neutron reflection have been used to investigate how solution pH, salt concentration surface...

10.1098/rsif.2012.0148 article EN cc-by Journal of The Royal Society Interface 2012-05-02

<b><i>Background:</i></b> Digital biomarkers that measure physical activity and mobility are of great interest in the assessment chronic diseases such as rheumatoid arthritis, it provides insights on patients’ quality life can be reliably compared across a whole population. <b><i>Objective:</i></b> To investigate feasibility analyzing iPhone sensor data collected remotely by means mobile software application order to derive meaningful...

10.1159/000506860 article EN cc-by-nc-nd Digital Biomarkers 2020-04-30

A novel film bulk acoustic resonator (FBAR) with two resonant frequencies which have opposite reactions to temperature changes has been designed. The modes respond differently in and pressure, the frequency shift being linearly correlated pressure changes. By utilizing FBAR's sealed back trench as a cavity, an on-chip single FBAR sensor suitable for measuring simultaneously is proposed demonstrated. experimental results show that coefficient of lower peak sensors approximately −17.4 ppm...

10.1088/0960-1317/22/12/125005 article EN Journal of Micromechanics and Microengineering 2012-10-25

Highly c-axis oriented ZnO films have been deposited at room temperature with high rates (∼50 nm·min−1) using an innovative remote plasma sputtering configuration, which allows independent control of the density and ion energy. The possess excellent crystallographic orientation, resistivity (>109 Ω·m), exhibit very low surface roughness. ability to increase energy without causing unwanted Ar+ bombardment onto substrate has shown be crucial for growth orientation need heating. In...

10.1063/1.4736541 article EN Journal of Applied Physics 2012-07-01

The characteristics and dispersion of the distinct surface acoustic waves (SAWs) propagating in ZnO/GaAs heterostructures have been studied experimentally theoretically. Besides Rayleigh mode, strong Sezawa modes, which propagate confined overlayer, arise due to smaller sound velocity ZnO than substrate. design parameters structure providing strongest piezoelectric field at a given depth within layered system for different modes determined. mode is shown be more 10 times stronger interface...

10.1063/1.3660215 article EN Journal of Applied Physics 2011-11-15
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