О. А. Пономарева

ORCID: 0000-0001-5634-6690
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About
Contact & Profiles
Research Areas
  • Zeolite Catalysis and Synthesis
  • Catalysis and Oxidation Reactions
  • Mesoporous Materials and Catalysis
  • Catalytic Processes in Materials Science
  • Catalysis and Hydrodesulfurization Studies
  • Catalysis for Biomass Conversion
  • Chemical Synthesis and Characterization
  • Pain Mechanisms and Treatments
  • Neuroscience and Neuropharmacology Research
  • Neuropeptides and Animal Physiology
  • Transportation Systems and Safety
  • Ion channel regulation and function
  • Economic and Technological Developments in Russia
  • Foreign Language Teaching Methods
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Nanomaterials for catalytic reactions
  • Advanced Data Processing Techniques
  • Metal-Organic Frameworks: Synthesis and Applications
  • Organophosphorus compounds synthesis
  • Analytical Chemistry and Chromatography
  • Advanced NMR Techniques and Applications
  • Asymmetric Hydrogenation and Catalysis
  • Ammonia Synthesis and Nitrogen Reduction
  • Cybersecurity and Information Systems
  • Industrial Engineering and Technologies

Lomonosov Moscow State University
2015-2024

Texas Tech University Health Sciences Center
2022-2024

Texas Tech University
2022-2024

A.V. Topchiev Institute of Petrochemical Synthesis
2012-2023

Ural Federal University
2021-2023

Moscow State University
2009-2023

Ural State University of Railway Transport
2023

Russian Academy of Sciences
2013-2022

Central Economics and Mathematics Institute
2022

Ufa Institute of Chemistry
2001

Introduction: Pain is a clinically relevant health care issue with limited therapeutic options, creating the need for new and improved analgesic strategies. The amygdala limbic brain region critically involved in regulation of emotional-affective components pain modulation. central nucleus (CeA) serves major output functions receives nociceptive information via external lateral parabrachial (PB). While neuroplasticity has been linked causally to behaviors, non-neuronal mechanisms this remain...

10.3389/fphar.2024.1368634 article EN cc-by Frontiers in Pharmacology 2024-03-21

Functional pain syndromes (FPS) occur in the absence of identifiable tissue injury or noxious events and include conditions such as migraine, fibromyalgia, others. Stressors are very common triggers attacks various FPS conditions. It has been recently demonstrated that kappa opioid receptors (KOR) central nucleus amygdala (CeA) contribute to conditions, but underlying mechanisms remain unclear. The CeA is rich KOR encompasses major output pathways involving extra-amygdalar projections...

10.3389/fphar.2022.903978 article EN cc-by Frontiers in Pharmacology 2022-05-25

Chronic pain presents a therapeutic challenge due to the highly complex interplay of sensory, emotional-affective and cognitive factors. The mechanisms transition from acute chronic are not well understood. We hypothesized that neuroimmune in amygdala, brain region involved component modulation, play an important role through high motility group box 1 (Hmgb1), pro-inflammatory molecule has been linked signaling spinal nociception. Transcriptomic analysis revealed upregulation Hmgb1 mRNA...

10.3390/ijms241511944 article EN International Journal of Molecular Sciences 2023-07-26

Neuroplasticity in the amygdala and its central nucleus (CeA) is linked to pain modulation behaviors, but cellular mechanisms are not well understood. Here, we addressed role of small-conductance Ca2+-activated potassium (SK) channels pain-related plasticity. The facilitatory effects intra-CeA application an SK channel blocker (apamin) on behaviors control rats were lost a neuropathic model, whereas activator (NS309) inhibited sham controls, suggesting loss inhibitory behavioral channels....

10.3390/cells13121055 article EN cc-by Cells 2024-06-18
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