A5002462192- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Cytomegalovirus and herpesvirus research
- Organ Donation and Transplantation
- Polyomavirus and related diseases
- Pharmacological Effects and Toxicity Studies
- Viral-associated cancers and disorders
- Neurological Complications and Syndromes
- Hepatitis C virus research
- Immune Cell Function and Interaction
- Dialysis and Renal Disease Management
- T-cell and B-cell Immunology
- Acute Kidney Injury Research
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- Metabolomics and Mass Spectrometry Studies
- Pregnancy and Medication Impact
- Erythropoietin and Anemia Treatment
- Liver Disease and Transplantation
- Parathyroid Disorders and Treatments
- Systemic Lupus Erythematosus Research
- Hepatitis B Virus Studies
- Pneumocystis jirovecii pneumonia detection and treatment
Shahid Beheshti University of Medical Sciences
2016-2025
Bielefeld University
2024
Hospital Labbafinejad
2003-2021
Shahid Beheshti University
2003-2021
American Society of Nephrology
2020
Shiraz University of Medical Sciences
2015
Baqiyatallah University of Medical Sciences
2005-2012
University of Tehran
2007
Ministry of Health and Medical Education
2001-2005
IgA nephropathy is the most common cause of primary glomerulonephritis. There are different pathologic biopsy-based scoring systems in use, but there no consensus among nephrologists yet regarding best classification method. Our aim was to test urine proteomics as a non-invasive method for nephropathy. This pursued by discovering novel prognostic protein biomarkers urine, and linking them pathogenesis disease through known signaling metabolic pathways. 13 samples patients with biopsy-proven...
Background Transplant recipients are given an immunosuppressive regimen such as tacrolimus to prevent organ rejection. Suprotac® is a generic that utilized in kidney transplantation Iran. This post-market study was conducted evaluate the safety and efficacy of comparison with Prograf®. Methods: In this two-armed, open-label, parallel, active-controlled, cohort study, de novo transplant aging 18 65 years were prescribed or Prograf® part immunosuppressant protocol. The primary outcome...
SUMMARY: Hepatitis C virus (HCV) infection is common among patients undergoing haemodialysis, and liver disease an important cause of morbidity mortality in this population. Management HCV‐related a major health concern with end‐stage renal (ESRD) haemodialysis. To investigate the prevalence HCV on haemodialysis its associated risk factors, we conducted prospective case series study 838 Tehran, Iran. Patients were selected randomly (cluster sampling) all screened for anti‐HCV antibodies,...
Chronic kidney disease (CKD) and end-stage renal (ESRD) are emerging as globally important public health problems, will necessitate improvements in health-care policy. ESRD incidence/prevalence data not available from large parts of the developing world. The main objective this study is to describe assess current clinical practices for patients on maintenance haemodialysis (HD) living province Tehran.In December 2005, an observational was performed with 2630 (1505 males 1125 females) 56...
Focal segmental glomerulosclerosis (FSGS) is a glomerular scarring disease diagnosed mostly by kidney biopsy. Since there currently no diagnostic test that can accurately predict steroid responsiveness in FSGS, prediction of the patients to therapy with noninvasive means has become critical issue. In present study urinary proteomics was used as tool discover potential predictive biomarkers.Urinary proteome 10 (n = 6 steroid-sensitive, n 4 steroid-resistant) biopsy proven FSGS analyzed using...
This study was designed to investigate the effects of combined administration lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure, serum advanced glycation end-products, nitric oxide (NO), endothelin-1 in patients with diabetic nephropathy. Thirty-four were randomly assigned either a supplement group or placebo group. The received 800 mg 80 daily for 12 weeks, whereas corresponding placebos. Urinary albumin, malondialdehyde (MDA), systolic pressure decreased...
Background . Focal segmental glomerulosclerosis (FSGS) is a glomerular injury with various pathogenic mechanisms. Urine proteome panel might help in noninvasive diagnosis and better understanding of pathogenesis FSGS. Method We have analyzed the urine sample 11 biopsy-proven FSGS subjects, 8 healthy controls, 6 patients IgA nephropathy (disease controls) by means liquid chromatography tandem mass spectrometry (nLC-MS/MS). Multivariate analysis quantified proteins was performed principal...
Tuberculosis (TB) is an important cause of morbidity and mortality in renal transplant recipients and, because its infrequency the lack medical awareness, it usually misdiagnosed. This study was carried out to determine frequency weight multiple risk factors for post kidney transplantation TB.A total 44 cases (0.3%), 12,820 patients from 12 major centers Iran 1984 2003, were compared with 184 healthy subjects who transplanted by same surgical team.The mean age controls 37.7 (13-63) 35.6...
Focal segmental glomerulosclerosis (FSGS) is a type of nephrotic syndrome which diagnosed by renal biopsy. Degree the proteinuria, dysfunction, histologic findings and response to therapy are some factors used for evaluating prognosis FSGS.In present study, we attempted discover protein candidates disease related glomerular filtration rate (renal dysfunction).Urine samples were collected from ten patients. Urine proteome was extracted trypsinated. Digested peptides separated identified...
Membranous glomerulonephritis (MGN) is one of the most frequent causes nephrotic syndrome in adults. It characterized by thickening glomerular basement membrane renal tissue. The current diagnosis MGN based on biopsy and detection antibodies to few podocyte antigens. Due limitations diagnostic methods, including invasiveness lack sensitivity biomarkers, there a requirement identify more applicable biomarkers. present study aimed metabolites that are involved development disease using...
Focal segmental glomerulosclerosis (FSGS) is a common glomerulonephritis, and its rates of occurrence are increasing worldwide. Proteinuria clinical defining feature FSGS which correlates with the severity podocyte injury in patients nephrotic‐range protein excretion. Metabolite biomarkers corresponding level proteinuria could be considered as non‐invasive complementary prognostic factors to proteinuria. The urine samples 15 ( n = 6 women 9 men) biopsy‐proven were collected subjected nuclear...
Abstract Background With COVID‐19 pandemic, concerns about kidney transplant recipients are rising. However, the incidence, clinical course, outcome, and predictive factors of disease severity obscured. Methods We describe laboratory manifestations, radiologic findings, finally outcome with pneumonia. Results Of 2493 under follow‐up in our clinic, 19 cases (4 diagnosed based on findings) were admitted. The mean age patients was 47.6 ± 12.4 years, time from transplantation 115.6 70.3 months....