A5005091031- Psoriasis: Treatment and Pathogenesis
- Biochemical Analysis and Sensing Techniques
- Pregnancy and Medication Impact
- Pharmaceutical studies and practices
- Neuropeptides and Animal Physiology
- Regulation of Appetite and Obesity
Sun Pharma (United States)
2019
Washington State University
2011
Previous reports suggest that glucagon-like peptide (GLP-1), a secreted from the distal small intestine, is an endocrine satiation signal. Nevertheless, there are conflicting regarding site where circulating GLP-1 acts to reduce food intake. To test hypothesis vagal afferents necessary for reduction of intake by GLP-1, we measured 15% sucrose during intravenous infusion in intact, vagotomized, and capsaicin-treated rats. We also cholecystokinin, known via abdominal afferents. found was not...
Objectives To compare treatment patterns and costs among psoriasis patients with without metabolic conditions newly initiating a biologic or apremilast.Methods Adult included had ≥1 prescription for secukinumab, adalimumab, ustekinumab, etanercept, apremilast between 01/01/2015 08/31/2018 (date of first was index date) no drug use in the 12-months pre-index, continuous enrollment 12-month pre-index 24-month post-index periods. Patients were divided into mutually exclusive cohorts stratified...