A5040742543- Healthcare Policy and Management
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Psoriasis: Treatment and Pathogenesis
- Hemophilia Treatment and Research
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical studies and practices
- Lung Cancer Research Studies
- Acute Lymphoblastic Leukemia research
- Neutropenia and Cancer Infections
- Lipoproteins and Cardiovascular Health
- Pharmaceutical Economics and Policy
- Neuroendocrine Tumor Research Advances
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Cancer Treatment and Pharmacology
- Dental Research and COVID-19
- Chronic Myeloid Leukemia Treatments
- Migration and Labor Dynamics
- Migration, Health and Trauma
- Vitamin K Research Studies
- Influenza Virus Research Studies
- Public Health and Environmental Issues
- Racial and Ethnic Identity Research
- Pregnancy and Medication Impact
- Respiratory viral infections research
G1 Therapeutics (United States)
2022-2023
Triangle
2022-2023
IBM (United States)
2019-2021
Universidad Autónoma Metropolitana
2021
Duke Medical Center
2020
Truven Health Analytics (United States)
2013-2018
Queen Elizabeth II Health Sciences Centre
2018
Regeneron (United States)
2017
Sanofi (United States)
2017
Amgen (United States)
2017
Previous research shows that the health behavior of immigrants is favorable to native-born adults in United States. We utilize pooled data from 1998–2001 National Health Interview Surveys and multinomial logistic regression techniques build on this literature examine association between acculturation immigrant smoking alcohol use. also how relates behaviors by gender. Results indicate more acculturated women less positive than women. For men, seems make little difference for behavior. Thus,...
This retrospective, observational study assessed 2-year persistence and compliance by treatment, route of administration, dosing frequency in postmenopausal women initiating a new osteoporosis therapy. Two-year rates were higher receiving injectables compared with oral agents.
Abstract Background Myelosuppression is a major dose‐limiting complication of chemotherapy for patients with extensive‐stage small cell lung cancer (ES‐SCLC). The objective was to describe the burden myelosuppression, treatment patterns, and supportive care use among ES‐SCLC treated in US community oncology setting. Methods This retrospective cohort study used structured electronic medical record (EMR) data from Florida Cancer Specialists & Research Institute between January 2013...
ABSTRACT Background Adults ≥ 65 years of age have suboptimal influenza vaccination responses compared to younger adults due age‐related immunosenescence. Two vaccines were specifically developed enhance protection: MF59‐adjuvanted trivalent vaccine (aIIV3) and high‐dose egg‐based (HD‐IIV3e). Methods In a retrospective cohort study conducted using US electronic medical records linked claims data during the 2019–2020 season, we relative effectiveness (rVE) aIIV3 with HD‐IIV3e standard‐dose...
The rapid growth of the Mexican American population and its young age structure have focused increased attention on long-term prospects youth. This study explores generational differences among these youth, both within across schools, to determine whether assimilation has positive or negative consequences in long term for as a whole. A series logistic regression models with National Longitudinal Study Adolescent Health revealed that rates academic failure risk obesity were higher second...
In situ measurement of distal tracheal pressure (Ptr) via an intraluminal side-hole catheter (IC) has been used to determine endotracheal tube (Rett) and intrinsic patient (Rpt) resistances in intubated subjects. Because differences cross-sectional area between the (ETT) trachea, fluid dynamic principles predict that IC position should critically influence these results. Accordingly, aim this study was effect on Rett. Ptr recorded vitro through from 2 cm inside, at tip of, or outside ETT (7,...
Objectives. The purpose of this study was to explore generational differences in math/science enrollment and achievement among Mexican‐American students the role family school contexts these differences. Methods. We applied survey regression techniques data from 12,020 adolescents National Longitudinal Study Adolescent Health. Results. Native‐born had lower than their peers, especially after were taken into account. immigrants when enrolled such classes, but explained by greater level...
Objective To examine the role of patient, hospital, and community characteristics on racial ethnic disparities in in‐hospital postsurgical complications. Data Sources Healthcare Cost Utilization Project, 2011 State Inpatient Databases; American Hospital Association Annual Survey Hospitals; Area Health Resources Files; Centers for Medicare & Medicaid Services Compare database. Methods Nonlinear hierarchical modeling was conducted to odds patients experiencing any complication, as defined...
Stiffness has been associated to malignancy in prostate and breast, as well thyroid. Ultrasound elastography objectively measures tissue elasticity, previous studies have described it a high sensitivity specificity technique for the detection of malignant thyroid nodules high-risk populations. The aim was assess accuracy population with low risk malignancy. 128 consecutive patients nodular goiter were recruited. Elastography ultrasound-guided fine-needle aspiration performed. When suspected...
Liraglutide has been shown to significantly improve glycemic control and reduce body weight while minimizing the risk of hypoglycemia in adult patients with type 2 diabetes (T2D). This study aimed identify characteristics that predict clinical economic outcomes associated liraglutide therapy practice US.Using Truven Health MarketScan Laboratory Database, (A1C <7%) diabetes-related costs were evaluated T2D initiating between January 1, 2010 June 30, 2012. Patients required have ≥1 post-index...
Objectives To compare treatment patterns and costs among psoriasis patients with without metabolic conditions newly initiating a biologic or apremilast.Methods Adult included had ≥1 prescription for secukinumab, adalimumab, ustekinumab, etanercept, apremilast between 01/01/2015 08/31/2018 (date of first was index date) no drug use in the 12-months pre-index, continuous enrollment 12-month pre-index 24-month post-index periods. Patients were divided into mutually exclusive cohorts stratified...
Plaque psoriasis is a chronic disease requiring long-term therapy. However, real-world treatment patterns and costs are not well characterized. This study examined healthcare among patients newly initiating biologic or apremilast for moderate-to-severe plaque psoriasis. Included had ?1 prescription secukinumab, ixekizumab, adalimumab, ustekinumab, etanercept, between 01/01/2015 08/31/2018, no prior use of the index medication, continuous enrolment 12 months pre-index 24 post-index. Treatment...
High-intensity statins (HIS) are recommended by current treatment guidelines for patients with clinical atherosclerotic cardiovascular disease and should be administered soon after an acute coronary syndrome (ACS) event maintained thereafter. However, adherence to remains adequate. Statin utilization patterns during index hospitalization the first year ACS event, association between statin post-discharge economic outcomes, described. Retrospective, observational study of US adults from...
Abstract Background Patterns of antiretroviral therapy (ART) use and immunologic correlates vary globally, contemporary trends are not well described. Methods The REPRIEVE trial (Randomized Trial to Prevent Vascular Events in HIV) enrolled persons with human immunodeficiency virus (HIV) who were aged 40–75 years, receiving ART, had low-to-moderate cardiovascular disease risk. ART was summarized within Global Burden Disease (GBD) super-regions, adjusted linear logistic regression analyses...
BACKGROUND: Pediatric growth hormone deficiency (GHD) is a rare disorder of short stature that currently treated with daily injections somatropin. In addition to stature, GHD associated other comorbidities such as impaired musculoskeletal development, cardiovascular disease, and decreased quality life. OBJECTIVE: To analyze somatropin utilization, adherence, health care costs among children who had either Medicaid or commercial insurance. METHODS: Children (aged < 18 years) diagnosis between...
Aim: To describe the burden of chemotherapy-induced myelosuppression among chemotherapy-treated patients with extensive-stage small-cell lung cancer (ES-SCLC). Materials & methods: Occurrence grade ≥3 myelosuppressive hematological adverse events (HAEs), treatment patterns and healthcare resource utilization (HCRU) after chemotherapy initiation were evaluated using data from The US Oncology Network Non-network clinics (1/1/2015-12/31/2020). Results: Among laboratory values (Network: N =...
The mammalian cell-based quadrivalent inactivated influenza vaccine (IIV4c) has advantages over egg-based (IIV4e), as production using cell-derived candidate viruses eliminates the opportunity for egg adaptation. This study estimated relative effectiveness (rVE) of IIV4c versus IIV4e in preventing cardiorespiratory hospitalizations during 2019-2020 US season.We conducted a retrospective cohort electronic medical records linked to claims data individuals aged 18-64 years. We assessed rVE...
Pharmacologic treatment for psoriatic arthritis (PsA) includes traditional oral small molecules (OSMs), tumor necrosis factor inhibitors (TNFis), and newer therapies such as a phosphodiesterase-4 (PDE4) inhibitor Janus kinase inhibitor. We aimed to describe patterns health care costs treatment-naïve patients with active PsA initiating pharmacologic treatment.This was an observational, retrospective study.We assessed from the IBM MarketScan Research databases. calculated during 12-month...
Infections, cytopenia, and gastrointestinal (GI) toxicity are adverse events of special interest (AESI) affecting most relapsed Philadelphia chromosome-negative (Ph-) B-cell acute lymphocytic leukemia (ALL) patients. This study quantified real-world rates economic burden these among Ph- ALL patients in the United States.Adults with during 1 April 2009-31 October 2016 were selected from MarketScan® healthcare claims databases. Outcomes included proportions AESIs AESI-related costs 100 days...
The goal of this study was to evaluate the incidence, inpatient mortality, and economic burden hepatic veno-occlusive disease (VOD) in adults with B-cell acute lymphoblastic leukemia (ALL) United States.Using MarketScan Commercial Claims Encounters Database Medicare Supplemental Coordination Benefits Database, data for patients ALL from April 1, 2009, October 31, 2016, were extracted by using diagnosis codes. VOD identified based on clinical criteria expert opinions. Patients followed up...