A5088567641- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- COVID-19 Clinical Research Studies
- Cannabis and Cannabinoid Research
- Influenza Virus Research Studies
- Mosquito-borne diseases and control
- Homelessness and Social Issues
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Bipolar Disorder and Treatment
- Pharmacological Effects and Toxicity Studies
- Viral Infections and Vectors
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Blood disorders and treatments
- Vibrio bacteria research studies
- Viral Infections and Outbreaks Research
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- COVID-19 epidemiological studies
University of South Florida
2015-2025
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
2023
Centers for Disease Control and Prevention
2023
Emory University
2023
Atlanta VA Medical Center
2023
Rutgers, The State University of New Jersey
2023
Eli Lilly (United States)
2023
Bayer (Finland)
2023
E Ink (South Korea)
2023
The Centers
2023
Background. Elite controllers spontaneously suppress human immunodeficiency virus (HIV) viremia but also demonstrate chronic inflammation that may increase risk of comorbid conditions. We compared hospitalization rates and causes among elite to those immunologically intact persons with medically controlled HIV.
The clinical management of low-level viremia (LLV) remains unclear. objective this study was to investigate the association blips and LLV with virologic failure.We enlisted patients who newly enrolled into HIV Research Network between 2005 2015, had HIV-1 RNA more than 200 copies/ml, were either antiretroviral therapy (ART)-naive or ART-experienced not on ART. Patients included achieved suppression (≤50 two consecutive viral loads) at least loads following suppression. Blips (≥2 >51...
Alcohol consumption has been associated with poor antiretroviral therapy (ART) adherence but less is known about its relationship to HIV viral suppression, or whether certain drinking patterns have a stronger association than others. The objectives of this study were determine the different alcohol suppression and ART adherence, any associations mediated by adherence.This observational used baseline data from 619 HIV+ participants, recruited across 8 clinical community settings Florida as...
There are contradictory reports regarding the effects of protease inhibitors on ECG measures QT and PR interval durations. The effect interrupting use progression is also unknown.
Introduction: Florida remains a high-incidence, high-prevalence setting for HIV. Long-acting (LA) antiretroviral therapies (ART) could improve HIV-related outcomes and reduce transmission. This study identifies preferred LA ART characteristics classes of preference among people with HIV (PWH) in Florida. Methods: The Cohort enrolls adult PWH from six counties. In February 2023, best-worst scaling discrete choice experiment (BWDCE) was added which included 12 tasks three alternatives an...
Abstract Background HIV pre-exposure prophylaxis (PrEP), a powerful tool for prevention, has traditionally been taken as daily oral medication. Long-acting injectable (LAI) cabotegravir is superior to PrEP prevention and was approved use LAI-PrEP in 2021. We aimed evaluate the uptake of six-month persistence sexual health clinic. Participant characteristics (N=36) LAI: Long acting PrEP: Pre-exposure Methods In February 2023, an pilot implemented county clinic serving diverse patient...
Abstract Background Despite advancements in HIV treatment, there remains a significant gap understanding mortality rates among reproductive-aged women with the United States. To enhance evidence-based interventions, this study aims to delineate trends from 1999-2020, focusing on demographic characteristics such as age, race, and geographic regions. HIV-related AAMRs per 100,000 individuals stratified by race aged 15-44 States, 1999 2020. Methods This involved retrospective analysis using CDC...
<sec> <title>BACKGROUND</title> Ending the HIV Epidemic remains a high public health priority, and state of Florida continues to have prevalence incidence. </sec> <title>OBJECTIVE</title> The Cohort study seeks identify factors associated with Care Continuum HIV-related comorbidities, focus on potential impact alcohol consumption. <title>METHODS</title> Wave 3 enrolled persons aged 18+ from nine clinical, case management, community settings across 2020 2023. All participants completed...
In 2013, Florida had the highest rate of new HIV infections and only 56% persons living with (PLWH) were virally suppressed. response, we initiated a cohort in to better understand issues affecting health outcomes. This manuscript will describe procedures Cohort; summarize information regarding enrollment, follow-up, findings date; discuss challenges lessons learned during establishment multisite PLWH. Cohort participants enrolled from eight clinics community-based organizations...
Objectives HIV infection has been associated with an increased risk of chronic kidney disease ( CKD ). Little is known about the prevalence in individuals high CD 4 cell counts prior to initiation antiretroviral therapy ART We sought address this knowledge gap. Methods describe among 4637 ‐naïve adults (mean age 36.8 years) > 500 cells/μL at enrolment S trategic T iming A nti R etroviral reatment START ) study. was defined by estimated glomerular filtration rate eGFR < 60 mL/min/1.73 m...
Cholera, an acute diarrheal infection has become a major global threat. Vibrio cholerae the causative agent of cholera been responsible for six previous pandemics since 1817 that spanned four continents and Australia with seventh pandemic ongoing 1961. Two serogroups V. O1 O139 have ability to secrete enterotoxin potential cause epidemics. The prior were caused by classical biotype serogroup. However, emergence El Tor subsequent variants traits are main isolates in pandemic. Cholera...
Marijuana use is common among people living with HIV (PLWH), but its association antiretroviral therapy (ART) adherence unclear. This study examined the between reason for marijuana and ART in a sample of adults HIV.Participants (N=703) recruited from seven community health centers Florida completed 45-minute questionnaire assessing demographics, symptoms anxiety depression, adherence, substance use, including reasons use. was defined as proportion days last 30 participants did not miss any...
Background. Before implementation of the Patient Protection and Affordable Care Act (ACA) in 2014, 100 000 persons living with human immunodeficiency virus (HIV) (PLWH) lacked healthcare coverage relied on a safety net Ryan White HIV/AIDS Program support, local charities, or uncompensated care (RWHAP/Uncomp) to cover visits HIV providers. We compared provider before (2011–2013) versus after (first half 2014) ACA among total 28 374 PLWH followed up 4 sites Medicaid expansion states...
Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it unknown which PWH prefer this option. Using the Andersen Behavioral Model study identifies characteristics of greater preference for LAI ART. Cross-sectional data from Florida Cohort, enrolled adult community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence <90%) factors. ART was assessed via a single question...
To investigate the mechanisms of platelet kinetics in Strategies for Management Antiretroviral Therapy (SMART) study that demonstrated excess mortality with CD4 guided episodic antiretroviral therapy (ART) drug conservation compared continuous treatment viral suppression. Follow-up analyses stored plasma samples increased activation both inflammatory and coagulation pathways after stopping ART.SMART patients from sites determined platelets routinely.Platelet counts were retrospectively...
Cholera is a global disease that has persisted for millennia.The cholera toxin (CT) from Vibrio cholerae responsible the clinical symptoms of cholera.This hetero-hexamer (AB 5 ) complex consisting subunit A (CTA) with pentamer (B B (CTB).The importance AB pathogenesis established wild type O1 serogroup using known structural and functional data.However, its role not yet documented in other serogroups harboring sequence level residue mutations.The sequences different are available GenBank...