A5055120016- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Adolescent Sexual and Reproductive Health
- Reproductive Health and Contraception
- Neuroscience and Neural Engineering
- Urinary Tract Infections Management
- Pelvic floor disorders treatments
- HIV/AIDS Research and Interventions
- Bacterial Infections and Vaccines
- Genital Health and Disease
- Tuberculosis Research and Epidemiology
- Cervical Cancer and HPV Research
- Advanced Memory and Neural Computing
- Reproductive System and Pregnancy
- Parallel Computing and Optimization Techniques
- Primary Care and Health Outcomes
- Female Genital Mutilation/Cutting Issues
- Sex work and related issues
- Patient Satisfaction in Healthcare
- Neural dynamics and brain function
- HIV-related health complications and treatments
- Patient-Provider Communication in Healthcare
- Intimate Partner and Family Violence
- Sexual Assault and Victimization Studies
- 3D Printing in Biomedical Research
Regeneron (United States)
2023-2025
University Hospitals Birmingham NHS Foundation Trust
2016-2025
Rush University
2024
Leeds Beckett University
2024
University of Oxford
2024
NIHR Surgical Reconstruction and Microbiology Research Centre
2012-2023
University of Birmingham
2013-2023
Mid Atlantic Epilepsy and Sleep Center
2022
Emory University
2007-2022
Whittier Street Health Center
1999-2020
Many architects believe that major improvements in cost-energy-performance must now come from domain-specific hardware. This paper evaluates a custom ASIC---called Tensor Processing Unit (TPU) --- deployed datacenters since 2015 accelerates the inference phase of neural networks (NN). The heart TPU is 65,536 8-bit MAC matrix multiply unit offers peak throughput 92 TeraOps/second (TOPS) and large (28 MiB) software-managed on-chip memory. TPU's deterministic execution model better match to...
Many architects believe that major improvements in cost-energy-performance must now come from domain-specific hardware. This paper evaluates a custom ASIC---called Tensor Processing Unit (TPU) --- deployed datacenters since 2015 accelerates the inference phase of neural networks (NN). The heart TPU is 65,536 8-bit MAC matrix multiply unit offers peak throughput 92 TeraOps/second (TOPS) and large (28 MiB) software-managed on-chip memory. TPU's deterministic execution model better match to...
Gonorrhoea is a major public health concern globally. Of particularly grave that resistance to the extended-spectrum cephalosporins has emerged during most recent years. This guideline provides recommendations regarding diagnosis and treatment of gonorrhoea in Europe. Compared outdated 2009 European guideline, this 2012 up-to-date guidance on, broader indications for testing gonorrhoea; introduction dual antimicrobial therapy (ceftriaxone 500 mg azithromycin 2 g) uncomplicated when...
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered use under the comprehensive in vitro proarrhythmia assay (CiPA). We studied effects 26 drugs 3 drug combinations on 2 commercially available iPSC-CM types using high-throughput voltage-sensitive dye microelectrode-array assays CiPA initiative compared results with clinical QT prolongation torsade de pointes (TdP) risk. Concentration-dependent...
Gonorrhoea is a major public health concern globally. Increasing incidence and sporadic ceftriaxone-resistant cases, including treatment failures, are growing concerns. The 2020 European gonorrhoea guideline provides up-to-date evidence-based guidance regarding the diagnosis of gonorrhoea. updates recommendations emphasize significantly increasing incidence; broad indications for increased testing with validated quality-assured nucleic acid amplification tests culture; dual antimicrobial...
The European guideline for the management of pelvic inflammatory disease includes evidence-based advice on investigation and treatment (PID). It has been updated to acknowledge role Mycoplasma genitalium as an important cause PID with testing now recommended women presenting possible male partners confirmed M. infection. Recent evidence suggests that serious adverse events are uncommon when using moxifloxacin its use is a first-line therapy, especially in those PID. potential utility MRI...
Abstract This guideline is an update of the 2011 European Guideline for Management Anogenital Warts. It intended to support best practice in care patients with anogenital warts by including evidence‐based recommendations on diagnosis, treatment, follow‐up and advice patients. use healthcare professionals sexual or dermato‐venereology clinics Europe but may be adapted other settings where management undertaken. As a guideline, should according national circumstances systems. Despite...
Gonorrhoea is a common sexually transmitted infection for which ceftriaxone the current first-line treatment, but antimicrobial resistance emerging. The objective of this study was to assess effectiveness gentamicin as an alternative (both combined with azithromycin) treatment gonorrhoea.G-ToG multicentre, parallel-group, pragmatic, randomised, non-inferiority trial comparing patients gonorrhoea. patients, treating physician, and assessing physician were masked nurse not. took place at 14...
The cardiac action potential (AP) is vital for understanding healthy and diseased biology drug safety testing. However, techniques high throughput AP measurements have been limited. Here, we introduce a novel technique reliably increasing the coupling of cardiomyocyte syncytium to planar multiwell microelectrode arrays, resulting in stable, label-free local extracellular (LEAP). We characterized reliability stability LEAP, its relationship field potential, efficacy quantifying morphology...
Abstract This guideline intents to offer guidance on the diagnosis and management of patients with gastrointestinal symptoms a suspected sexually transmitted cause. Proctitis is defined as an inflammatory syndrome anal canal and/or rectum. Infectious proctitis can be via genital–anal mucosal contact, but some also digital contact toys. Neisseria gonorrhoeae, Chlamydia trachomatis (including lymphogranuloma venereum), Treponema pallidum herpes simplex virus are most common anorectal...
This study examines the distribution of selected sexually transmitted infections (STIs) in older people (aged >/=45 years) attending genitourinary medicine (GUM) clinics West Midlands, UK.Analysis data from regional enhanced STI surveillance system for period 1996-2003. Selected STIs were chlamydia, genital herpes, warts, gonorrhoea and syphilis.Altogether, 4445 episodes reported among during period. Between 1996 2003 accounted 3.7% 4.3%, respectively, all GUM clinic attendances. The rate...
To estimate the loss of quality life and cost treatment associated with genital warts seen in sexual health clinics.A cross-sectional questionnaire study case note review individuals warts, carried out eight clinics England Northern Ireland. Individuals attending participating were invited to take part study. 895 participants recruited. A separate sample 370 who had attended a clinic first visit for or recurrent episode between April June 2007 was included review. Quality measured using...
Proctitis is defined as an inflammatory syndrome of the distal 10–12 cm anal canal, also called rectum. Infectious proctitis can be sexually transmitted via genital-anal mucosal contact, but some mutual masturbation. N. gonorrhoeae, C. trachomatis (including lymphogranuloma venereum), Herpes Simplex Virus and T. pallidum are most common anorectal pathogens. Shigellosis transferred oral-anal contact may lead to proctocolitis or enteritis. Although studies on these infections have concentrated...
In this paper, we introduce the Tensor Streaming Processor (TSP) architecture, a functionally-sliced microarchitecture with memory units interleaved vector and matrix deep learning functional in order to take advantage of dataflow locality operations. The TSP is built based on two key observations: (1) machine workloads exhibit abundant data parallelism, which can be readily mapped tensors hardware, (2) simple deterministic processor producer-consumer stream programming model enables precise...
Microprocessors continue on the relentless path to provide more performance. Every new innovation in computing-distributed computing Internet, data mining, Java programming, and multimedia streams-requires cycles power. Even traditional applications such as databases numerically intensive codes present increasing problem sizes that drive demand for higher Design innovations, compiler technology, manufacturing process improvements, integrated circuit advances have been driving exponential...
The changing epidemiology of genital herpes in Edinburgh is described relation to simplex virus (HSV) Type 1 and 2 infection over a period 14 years.2018 episodes 1794 patients year were assessed. Data on age, sex, sexual orientation, geographical origin antibodies also analysed.The proportion cases that HSV increased the from approximately 20% 40%. more common young, women as primary infection.HSV increasing importance cause our population. This may reflect changes attitudes practises past decade.