George‐Sorin Ţiplica

ORCID: 0000-0002-8719-6952
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About
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Research Areas
  • Dermatology and Skin Diseases
  • Contact Dermatitis and Allergies
  • Autoimmune Bullous Skin Diseases
  • Nail Diseases and Treatments
  • Cutaneous Melanoma Detection and Management
  • Syphilis Diagnosis and Treatment
  • Nonmelanoma Skin Cancer Studies
  • Cancer and Skin Lesions
  • Cutaneous lymphoproliferative disorders research
  • Dermatologic Treatments and Research
  • Drug-Induced Adverse Reactions
  • Genital Health and Disease
  • Acne and Rosacea Treatments and Effects
  • Allergic Rhinitis and Sensitization
  • Reproductive tract infections research
  • Dermatological diseases and infestations
  • Skin and Cellular Biology Research
  • Genetic and rare skin diseases.
  • Urticaria and Related Conditions
  • Skin Protection and Aging
  • Psoriasis: Treatment and Pathogenesis
  • Occupational exposure and asthma
  • Eosinophilic Disorders and Syndromes
  • Parvovirus B19 Infection Studies
  • Hair Growth and Disorders

Carol Davila University of Medicine and Pharmacy
2016-2025

Spitalul Clinic Colentina
2012-2025

ERN Skin
2024

European Clinical Research Infrastructure Network
2021

Hai phong University Of Medicine and Pharmacy
2020

Institut Alfred Fournier
2015

Assistance Publique – Hôpitaux de Paris
2015

Royal South Hants Hospital
2015

Avila University
2013

Gonorrhoea is a major public health concern globally. Of particularly grave that resistance to the extended-spectrum cephalosporins has emerged during most recent years. This guideline provides recommendations regarding diagnosis and treatment of gonorrhoea in Europe. Compared outdated 2009 European guideline, this 2012 up-to-date guidance on, broader indications for testing gonorrhoea; introduction dual antimicrobial therapy (ceftriaxone 500 mg azithromycin 2 g) uncomplicated when...

10.1177/0956462412472837 article EN International Journal of STD & AIDS 2013-02-01

Syphilis remains a major public health problem in Europe (both Eastern since the 1990's and Western re-emergence of disease late 1990's-early 2000's).This guideline is an update IUSTI: 2008 European on management syphilis produced by Guideline Editorial Board (http://www.iusti.org/regions/Europe/pdf/2013/Editorial_Board.pdf) EDF Committee.It provides recommendations concerning diagnosis Europe. Major advances include (1) broader use PCR, immunohistochemistry, subtyping etiological agent...

10.1111/jdv.12734 article EN Journal of the European Academy of Dermatology and Venereology 2014-10-27

Abstract Scabies is caused by Sarcoptes scabiei var. hominis . The disease can be sexually transmitted. Patients’ main complaint nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts may associated with reduced or absent pruritus. Recommended treatments permethrin 5% cream, oral ivermectin benzyl benzoate 25% lotion. Alternative malathion 0.5% aqueous lotion, 1% lotion sulphur 6–33%...

10.1111/jdv.14351 article EN Journal of the European Academy of Dermatology and Venereology 2017-06-22

Abstract The 2020 edition of the European guideline on management syphilis is an update 2014 edition. Main modifications and updates include: ongoing epidemics early in Europe, particularly men who have sex with (MSM) development dual treponemal non‐treponemal point‐of‐care (POC) tests progress test (NTT) automatization regular episodic shortage benzathine penicillin G (BPG) some countries exclusion azithromycin as alternative treatment at any stage pre‐exposure or immediate post‐exposure...

10.1111/jdv.16946 article EN Journal of the European Academy of Dermatology and Venereology 2020-10-22

Data sharing is not applicable to this article as no new data were created or analysed in study.

10.1111/jdv.18102 article EN Journal of the European Academy of Dermatology and Venereology 2022-04-12

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug reactions associated with a high rate of mortality morbidity. There is no consensus on the treatment strategy.To explore approaches across Europe outcomes SJS/TEN disease course, as well risk factors culprit drugs.A retrospective pan-European multicenter cohort study including 13 referral centers belonging to ToxiTEN ERN-skin subgroup was conducted. A total 212 adults were included between January 1, 2015,...

10.1001/jamadermatol.2021.3154 article EN JAMA Dermatology 2021-08-25

Abstract Genital herpes is one of the most common sexually transmitted infections worldwide. Using best available evidence, this guideline recommends strategies for diagnosis, management and follow‐up condition as well minimizing transmission. Early recognition initiation therapy key may reduce duration illness or avoid hospitalization with complications, including urinary retention, meningism severe systemic illness. The covers a range clinical scenarios, such recurrent genital herpes,...

10.1111/jdv.20450 article EN cc-by-nc-nd Journal of the European Academy of Dermatology and Venereology 2024-12-02

Abstract Background Hydration with topical emollients forms the backbone of treatment for mild atopic dermatitis ( AD ), but few randomized controlled trials have assessed their efficacy in young children. Objectives Assess and tolerability long‐term emollient therapy moderate to severe xerosis children . Methods This was a phase III , multicentre, double‐blind, randomized, vehicle‐controlled trial. Children n = 251) aged 2–6 years ‐associated were 1 : 28‐day an combining glycerol paraffin...

10.1111/jdv.12314 article EN Journal of the European Academy of Dermatology and Venereology 2013-11-25

Abstract Pediculosis pubis is caused by Phthirus pubis. The disease can be sexually transmitted. Patients main complain of itch in the pubic area. parasite spotted with naked eye and blue macules observed First line therapy consists permethrin or pyrethrins piperonyl butoxide. Second contains phenothrin, malathion oral ivermectin. Partner management needs a look‐back period time 3 months. Pubic lice incidence increased populations groups living crowded spaces scarce sanitary conditions as...

10.1111/jdv.14420 article EN Journal of the European Academy of Dermatology and Venereology 2017-07-16

Background Supportive care is the cornerstone of management adult and paediatric Stevens–Johnson syndrome (SJS) toxic epidermal necrolysis (TEN). However, consensus on modalities supportive lacking. Objectives Our aim in this international multicentric Delphi exercise was to establish a multidisciplinary expert standardize recommendations regarding acute phase SJS/TEN. Methods Participants were sent survey via online tool SurveyMonkey, consisting 103 statements organized into 11 topics: team...

10.1111/bjd.19893 article EN British Journal of Dermatology 2021-03-03

Abstract Acute generalized exanthematous pustulosis (AGEP) is a rare, usually drug‐induced, acute pustular rash. Despite the lack of strong data supporting effectiveness topical or systemic corticosteroids in this drug reaction, they are widely used. More generally, there no consensus on diagnostic modalities and management patients with AGEP. We aimed to provide European expert recommendations for diagnosis Members ToxiTEN group Reference Network (ERN)‐skin, all dermatologists and/or...

10.1111/jdv.20232 article EN cc-by-nc-nd Journal of the European Academy of Dermatology and Venereology 2024-07-18

Background: Matrix metalloproteinase (MMP)1, MMP9, MMP11, and MMP13 are overexpressed in malignant melanoma (MM), being associated with tumor invasive phase, metastases, more aggressive neoplastic phenotypes.Aim: The main objective of the current study was to correlate expression MMPs evolution MM toward distant metastasis.Patients, Materials Methods: We designed a retrospective cohort study, including 13 patients metastatic MM.Data concerning age, sex, localization primary lesion...

10.47162/rjme.65.1.06 article EN Romanian Journal of Morphology and Embryology 2024-03-23

Acne vulgaris is a disorder of the pilosebaceous unit in which androgens contribute to its onset and persistence. The use antiandrogens therefore potentially effective; however, for topical are not available on market. Cortexolone 17α-propionate (CB-03-01; Cosmo S.p.A, Lainate, Italy) new potent antiandrogen useful acne vulgaris.To evaluate safety efficacy CB-03-01 1% cream as compared with placebo tretinoin 0·05% (Retin-A® ; Janssen-Cilag).Seventy-seven men facial scored 2-3 according...

10.1111/j.1365-2133.2011.10332.x article EN British Journal of Dermatology 2011-03-24

Abstract Background Partner management is the process of identifying contacts a person infected by sexually transmitted infection ( STI ) and referral to health care provider for appropriate management. It represents public activity. Methods This guideline produced IUSTI European Guideline Editorial Board EDF Committee. Results provides recommendations concerning infections that require partner management, lookback periods this main steps follow (offering support patients, notifying...

10.1111/jdv.13181 article EN Journal of the European Academy of Dermatology and Venereology 2015-05-07

Abstract Background Work‐related solar ultraviolet radiation ( UVR ) is an important factor in the pathogenesis of non‐melanoma skin cancer NMSC ). The World Health Organization, through International Agency for Research on Cancer, has classified as a group 1 carcinogen since 2012. main problems encountered so far study occupationally induced include lack accurate occupational dosimetry well insufficient distinction between and leisure exposure underreporting . Objectives aim this was to...

10.1111/jdv.16303 article EN Journal of the European Academy of Dermatology and Venereology 2020-02-21

Abstract Background Long-term sequelae are frequent and often disabling after epidermal necrolysis (Stevens-Johnson syndrome (SJS) toxic (TEN)). However, consensus on the modalities of management these is lacking. Objectives We conducted an international multicentric DELPHI exercise to establish a multidisciplinary expert standardize recommendations regarding SJS/TEN sequelae. Methods Participants were sent survey via online tool “Survey Monkey” consisting 54 statements organized into 8...

10.1186/s13023-023-02631-7 article EN cc-by Orphanet Journal of Rare Diseases 2023-02-22

Abstract Background Emollients are considered as a first‐line therapy for the treatment of atopic dermatitis ( AD ). However, evidence‐based proof that regular use emollients reduces severity is lacking. Objective To assess whether results in reduction children with . Methods In this multicentre randomized, parallel group, open‐label study, mild‐to‐moderate were recruited during flare. After flare resolution topical corticosteroid, patients randomized to V0034 CR emollient, reference...

10.1111/jdv.14849 article EN Journal of the European Academy of Dermatology and Venereology 2018-02-08
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