A5025263130- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Contact Dermatitis and Allergies
- Cutaneous Melanoma Detection and Management
- Autoimmune Bullous Skin Diseases
- Nonmelanoma Skin Cancer Studies
- Syphilis Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Dermatologic Treatments and Research
- Cancer and Skin Lesions
- Drug-Induced Adverse Reactions
- Reproductive tract infections research
- Acne and Rosacea Treatments and Effects
- Genital Health and Disease
- Dermatological diseases and infestations
- Allergic Rhinitis and Sensitization
- Skin and Cellular Biology Research
- Genetic and rare skin diseases.
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Skin Protection and Aging
- Eosinophilic Disorders and Syndromes
- Parvovirus B19 Infection Studies
- Occupational exposure and asthma
- Herpesvirus Infections and Treatments
Carol Davila University of Medicine and Pharmacy
2016-2025
Spitalul Clinic Colentina
2012-2025
ERN Skin
2024
European Clinical Research Infrastructure Network
2021
Hai phong University Of Medicine and Pharmacy
2020
Institut Alfred Fournier
2015
Assistance Publique – Hôpitaux de Paris
2015
Royal South Hants Hospital
2015
Avila University
2013
Gonorrhoea is a major public health concern globally. Of particularly grave that resistance to the extended-spectrum cephalosporins has emerged during most recent years. This guideline provides recommendations regarding diagnosis and treatment of gonorrhoea in Europe. Compared outdated 2009 European guideline, this 2012 up-to-date guidance on, broader indications for testing gonorrhoea; introduction dual antimicrobial therapy (ceftriaxone 500 mg azithromycin 2 g) uncomplicated when...
Syphilis remains a major public health problem in Europe (both Eastern since the 1990's and Western re-emergence of disease late 1990's-early 2000's).This guideline is an update IUSTI: 2008 European on management syphilis produced by Guideline Editorial Board (http://www.iusti.org/regions/Europe/pdf/2013/Editorial_Board.pdf) EDF Committee.It provides recommendations concerning diagnosis Europe. Major advances include (1) broader use PCR, immunohistochemistry, subtyping etiological agent...
Abstract Scabies is caused by Sarcoptes scabiei var. hominis . The disease can be sexually transmitted. Patients’ main complaint nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts may associated with reduced or absent pruritus. Recommended treatments permethrin 5% cream, oral ivermectin benzyl benzoate 25% lotion. Alternative malathion 0.5% aqueous lotion, 1% lotion sulphur 6–33%...
Abstract The 2020 edition of the European guideline on management syphilis is an update 2014 edition. Main modifications and updates include: ongoing epidemics early in Europe, particularly men who have sex with (MSM) development dual treponemal non‐treponemal point‐of‐care (POC) tests progress test (NTT) automatization regular episodic shortage benzathine penicillin G (BPG) some countries exclusion azithromycin as alternative treatment at any stage pre‐exposure or immediate post‐exposure...
Data sharing is not applicable to this article as no new data were created or analysed in study.
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but potentially fatal drug hypersensitivity reaction. To our knowledge, there no international consensus on its severity assessment treatment.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug reactions associated with a high rate of mortality morbidity. There is no consensus on the treatment strategy.To explore approaches across Europe outcomes SJS/TEN disease course, as well risk factors culprit drugs.A retrospective pan-European multicenter cohort study including 13 referral centers belonging to ToxiTEN ERN-skin subgroup was conducted. A total 212 adults were included between January 1, 2015,...
Abstract Acute generalized exanthematous pustulosis (AGEP) is a rare, usually drug‐induced, acute pustular rash. Despite the lack of strong data supporting effectiveness topical or systemic corticosteroids in this drug reaction, they are widely used. More generally, there no consensus on diagnostic modalities and management patients with AGEP. We aimed to provide European expert recommendations for diagnosis Members ToxiTEN group Reference Network (ERN)‐skin, all dermatologists and/or...
Abstract Genital herpes is one of the most common sexually transmitted infections worldwide. Using best available evidence, this guideline recommends strategies for diagnosis, management and follow‐up condition as well minimizing transmission. Early recognition initiation therapy key may reduce duration illness or avoid hospitalization with complications, including urinary retention, meningism severe systemic illness. The covers a range clinical scenarios, such recurrent genital herpes,...
Abstract Background Hydration with topical emollients forms the backbone of treatment for mild atopic dermatitis ( AD ), but few randomized controlled trials have assessed their efficacy in young children. Objectives Assess and tolerability long‐term emollient therapy moderate to severe xerosis children . Methods This was a phase III , multicentre, double‐blind, randomized, vehicle‐controlled trial. Children n = 251) aged 2–6 years ‐associated were 1 : 28‐day an combining glycerol paraffin...
Abstract Pediculosis pubis is caused by Phthirus pubis. The disease can be sexually transmitted. Patients main complain of itch in the pubic area. parasite spotted with naked eye and blue macules observed First line therapy consists permethrin or pyrethrins piperonyl butoxide. Second contains phenothrin, malathion oral ivermectin. Partner management needs a look‐back period time 3 months. Pubic lice incidence increased populations groups living crowded spaces scarce sanitary conditions as...
Background Supportive care is the cornerstone of management adult and paediatric Stevens–Johnson syndrome (SJS) toxic epidermal necrolysis (TEN). However, consensus on modalities supportive lacking. Objectives Our aim in this international multicentric Delphi exercise was to establish a multidisciplinary expert standardize recommendations regarding acute phase SJS/TEN. Methods Participants were sent survey via online tool SurveyMonkey, consisting 103 statements organized into 11 topics: team...
Abstract Background Long-term sequelae are frequent and often disabling after epidermal necrolysis (Stevens-Johnson syndrome (SJS) toxic (TEN)). However, consensus on the modalities of management these is lacking. Objectives We conducted an international multicentric DELPHI exercise to establish a multidisciplinary expert standardize recommendations regarding SJS/TEN sequelae. Methods Participants were sent survey via online tool “Survey Monkey” consisting 54 statements organized into 8...
Acne vulgaris is a disorder of the pilosebaceous unit in which androgens contribute to its onset and persistence. The use antiandrogens therefore potentially effective; however, for topical are not available on market. Cortexolone 17α-propionate (CB-03-01; Cosmo S.p.A, Lainate, Italy) new potent antiandrogen useful acne vulgaris.To evaluate safety efficacy CB-03-01 1% cream as compared with placebo tretinoin 0·05% (Retin-A® ; Janssen-Cilag).Seventy-seven men facial scored 2-3 according...
Abstract Background Partner management is the process of identifying contacts a person infected by sexually transmitted infection ( STI ) and referral to health care provider for appropriate management. It represents public activity. Methods This guideline produced IUSTI European Guideline Editorial Board EDF Committee. Results provides recommendations concerning infections that require partner management, lookback periods this main steps follow (offering support patients, notifying...
Abstract Background Work‐related solar ultraviolet radiation ( UVR ) is an important factor in the pathogenesis of non‐melanoma skin cancer NMSC ). The World Health Organization, through International Agency for Research on Cancer, has classified as a group 1 carcinogen since 2012. main problems encountered so far study occupationally induced include lack accurate occupational dosimetry well insufficient distinction between and leisure exposure underreporting . Objectives aim this was to...
Background: Matrix metalloproteinase (MMP)1, MMP9, MMP11, and MMP13 are overexpressed in malignant melanoma (MM), being associated with tumor invasive phase, metastases, more aggressive neoplastic phenotypes.Aim: The main objective of the current study was to correlate expression MMPs evolution MM toward distant metastasis.Patients, Materials Methods: We designed a retrospective cohort study, including 13 patients metastatic MM.Data concerning age, sex, localization primary lesion...
Abstract Background Emollients are considered as a first‐line therapy for the treatment of atopic dermatitis ( AD ). However, evidence‐based proof that regular use emollients reduces severity is lacking. Objective To assess whether results in reduction children with . Methods In this multicentre randomized, parallel group, open‐label study, mild‐to‐moderate were recruited during flare. After flare resolution topical corticosteroid, patients randomized to V0034 CR emollient, reference...