Nathaniel T. Pickle

ORCID: 0000-0001-5676-7989
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About
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Research Areas
  • Balance, Gait, and Falls Prevention
  • Muscle activation and electromyography studies
  • Prosthetics and Rehabilitation Robotics
  • Cerebral Palsy and Movement Disorders
  • Sports Performance and Training
  • Nuclear Physics and Applications
  • Nuclear reactor physics and engineering
  • Vestibular and auditory disorders
  • Diabetic Foot Ulcer Assessment and Management
  • Obstructive Sleep Apnea Research
  • Atomic and Subatomic Physics Research
  • Particle Detector Development and Performance
  • Injury Epidemiology and Prevention
  • Spinal Cord Injury Research
  • Simulation and Modeling Applications
  • Magnetic confinement fusion research
  • Exercise and Physiological Responses
  • Health and Medical Research Impacts
  • X-ray Spectroscopy and Fluorescence Analysis
  • Superconducting Materials and Applications
  • 3D Shape Modeling and Analysis
  • Advanced Measurement and Metrology Techniques
  • Human Pose and Action Recognition
  • Cardiovascular and exercise physiology
  • Sensor Technology and Measurement Systems

CFD Research Corporation (United States)
2019-2025

Colorado School of Mines
2014-2022

New Jersey Institute of Technology
2021

U.S. Army Research Institute of Environmental Medicine
2021

The University of Texas at Dallas
2017-2019

Abilene Christian University
2010-2018

Purpose To assess physiological metrics during the use of a commercially available bilateral active ankle exoskeleton challenging military-relevant task and if this influences: metabolic load, measures or rate perceived exertion. Methods Nine healthy volunteers (5M, 4F) completed randomized cross-over design trial, with baseline visit two test sessions (with/without exoskeleton). Variables included impact on time to exhaustion walking treadmill at varying speeds gradients (0–15%) 26.7°C, 50%...

10.1371/journal.pone.0314613 article EN cc-by PLoS ONE 2025-01-24

Sloped walking is challenging for individuals with transtibial amputation (TTA) due to the functional loss of ankle plantarflexors. Prostheses that actively generate power may help restore this lost function. The purpose study was use musculoskeletal modeling and simulation quantify mechanical delivered body segments by passive powered prostheses remaining muscles in amputated intact legs during sloped walking. We generated simulations from experimental kinematic kinetic data on slopes 0, ±3...

10.1115/1.4037938 article EN Journal of Biomechanical Engineering 2017-10-03

The normalized $^{238}$U(n,f)/$^{235}$U(n,f) cross section ratio has been measured using the NIFFTE fission Time Projection Chamber from reaction threshold to $30$~MeV. fissionTPC is a two-volume MICROMEGAS time projection chamber that allows for full three-dimensional reconstruction of fission-fragment ionization profiles neutron-induced fission. measurement was performed at Los Alamos Neutron Science Center, where neutron energy determined time-of-flight. reported here first made with...

10.1103/physrevc.97.034618 article EN publisher-specific-oa Physical review. C 2018-03-23

Clinical balance assessments often rely on functional tasks as a proxy for (e.g., Timed Up and Go). In contrast, analyses of in research settings incorporate quantitative biomechanical measurements whole-body angular momentum, H) using motion capture techniques. Fully instrumenting patients the clinic is not feasible, thus it desirable to estimate quantities related from taken subset body segments. Machine learning algorithms are well-suited this type low- high-dimensional mapping. Thus, our...

10.1186/s12984-019-0550-8 article EN cc-by Journal of NeuroEngineering and Rehabilitation 2019-07-12

In Duchenne muscular dystrophy (DMD), one of the most severe and frequent genetic diseases in humans, dystrophic muscles are prone to damage caused by mechanical stresses during eccentric contractions. Eccentric contraction walking on level ground likely contributes progression degeneration lower limb muscles. However, little is known about how amount muscle contractions affected downhill/uphill sloped walking, which often encountered patients' daily lives poses different biomechanical...

10.3389/fbioe.2020.573666 article EN cc-by Frontiers in Bioengineering and Biotechnology 2020-10-14

Close to half people over 60 years of age experience vestibular dysfunction. Although rehabilitation has been proven effective in reducing dizziness and falls older adults, adherence exercise programs is a major issue reported be below 50%. Therefore, this research aimed develop an app with gaming elements improve exercises that are part rehabilitation, provide feedback increase the accuracy during performance. A clinician-informed design was used where five physical therapists were asked...

10.3389/fneur.2022.836571 article EN cc-by Frontiers in Neurology 2022-02-24

Vestibular hypofunction is associated with dizziness, imbalance, and blurred vision head movement. rehabilitation the gold standard recommendation to decrease symptoms improve postural stability. The Clinical Practice Guidelines for vestibular suggest home exercises 3-5 times daily, but patient adherence a problem, compliance rates often below 50%. An app was developed increase engagement by providing as games. This study compared accuracy of exercise performance in one-time session using...

10.3389/fmed.2023.1269874 article EN cc-by Frontiers in Medicine 2023-11-24

Maintaining balance on ramps is important for mobility. However, commonly assessed using inverted pendulum-based metrics (e.g., margin of stability), which may not be appropriate assessment human walking non-level surfaces. To investigate this, we analyzed stability four different pendulum models: extrapolated center mass (XCOM), foot placement estimate (FPE), neglecting angular momentum (FPENoH), and capture point (CAP). We experimental data from 10 able-bodied individuals a ramp at 0°,...

10.1371/journal.pone.0206875 article EN public-domain PLoS ONE 2018-11-05

Abstract Active ankle-foot prostheses generate mechanical power during the push-off phase of gait, which can offer advantages over passive prostheses. However, these benefits manifest primarily in joint kinetics (e.g., work) and energetics metabolic cost) rather than balance (whole-body angular momentum, H ), are typically constrained to push-off. The purpose this study was analyze differences between active non-amputees coordination throughout gait on ramps. We used Statistical Parametric...

10.1038/s41598-018-37581-9 article EN cc-by Scientific Reports 2019-02-04

Understanding the effects of an assistive device on dynamic balance is crucial, particularly for robotic leg prostheses. Analyses commonly evaluate range whole-body angular momentum (H). However, contributions individual body segments to overall H throughout gait may yield futher insights, specifically people with transtibial amputation using powered We evaluated segment Statistical Parametric Mapping assess prosthesis type (powered vs passive) and ramp angle segmental coordination. The...

10.1109/icorr.2017.8009478 article EN 2017-07-01

Abstract Background Locomotor transitions between different ambulatory tasks are essential activities of daily life. During these transitions, biomechanics affected by various factors such as anticipation, movement direction, and task complexity. These thought to influence the neuromotor regulation dynamic balance, which can be quantified using whole-body angular momentum ( H ). However, specific effects on balance during not well understood. The ability regulate in presence contextual is...

10.1186/s12984-020-00731-0 article EN cc-by Journal of NeuroEngineering and Rehabilitation 2020-07-18

Military personnel involved in weapon training are subjected to repeated low-level blasts. The prevailing method of estimating blast loads involves wearable gauges. However, using sensor data, the head or other organs cannot be accurately estimated without knowledge service member's body posture. An image/video-augmented complementary experimental-computational platform for conducting safer was developed. This study describes protocol automated generation scenes from video data exposure...

10.3791/66575 article EN Journal of Visualized Experiments 2024-12-06

Clinical balance assessments often rely on functional tasks as a proxy for (e.g., Timed lip and Go). In contrast, analyses of in research settings incorporate quantitative biomechanical measurements whole-body angular momentum, H) using motion capture techniques. Fully instrumenting patients the clinic is not feasible, thus it desirable to estimate quantities related from taken subset body segments. Machine learning algorithms are well-suited this type low- high-dimensional mapping. Thus,...

10.1109/embc.2018.8512530 article EN 2018-07-01

Abstract The residual reduction algorithm (RRA) in OpenSim is designed to improve dynamic consistency of kinematics and ground reaction forces movement simulations musculoskeletal models. RRA requires the user select numerous tracking weights for joint reduce errors. Selection often performed manually, which can be time-consuming unlikely yield optimal weights. A multi-heuristic optimization was used expedite weight decision making This method produced more rigorous results than manual...

10.1101/2021.10.06.463431 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-10-08
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