A5074063650- Genomics and Phylogenetic Studies
- Ovarian cancer diagnosis and treatment
- Genetic diversity and population structure
- Plant and Fungal Species Descriptions
- Gynecological conditions and treatments
- Endoplasmic Reticulum Stress and Disease
- Alcohol Consumption and Health Effects
- Cancer-related molecular mechanisms research
- Reproductive Biology and Fertility
- Tryptophan and brain disorders
- Ovarian function and disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Cardiac Imaging and Diagnostics
- Neuroinflammation and Neurodegeneration Mechanisms
- Magnetic Properties and Applications
- Advanced Glycation End Products research
- Plant Stress Responses and Tolerance
- Hearing Loss and Rehabilitation
- Acute Myocardial Infarction Research
- Microbial Natural Products and Biosynthesis
- RNA modifications and cancer
- Electromagnetic Simulation and Numerical Methods
- Industrial Technology and Control Systems
- Liver physiology and pathology
- Neurological Disease Mechanisms and Treatments
Taihe Hospital
2024-2025
Desert Forestry Experimental Center
2020-2024
Chinese Academy of Forestry
2020-2024
Hubei University of Medicine
2024
First Affiliated Hospital of Xi'an Jiaotong University
2014-2023
State Forestry and Grassland Administration
2022-2023
Liaoning Provincial People's Hospital
2011-2023
Zhumadian Central Hospital
2022
Nanjing University of Chinese Medicine
2016-2022
Jiangsu Province Hospital
2022
What changes in the mitochondria of human mural granulosa cells (mGCs) with maternal aging?The mitochondrial membrane potential (MMP) and ability oxidative phosphorylation (OXPHOS) mGCs declines reproductive aging, accompanied more abnormal mitochondria.Mitochondria play an important role dialogue between oocytes. However, underlying mechanism dysfunction aging is still poorly understood.In total, 149 infertile women underwent IVF ART Centre Chinese PLA General Hospital, China from September...
Stress is well known to contribute the development of both neurological and psychiatric diseases. In central nervous system, a role for STING (stimulator interferon genes) in modulating immunological responses has been widely suggested, this protein possesses neurotoxic neuroprotective properties. However, potential signalling pathway underlying regulatory mechanism chronic stress have not established. study, C57BL/6 mice were subjected intermittent restraint 14 days (6 h/day), sucrose...
Post-stroke anxiety (PSA) is a kind of affective disorder occurring after stroke, with as the primary clinical manifestation. PSA's mechanism unclear, and there are few prevention treatment measures. Our previous study found that HDAC3 could activate NF-κB signaling through mediated p65 deacetylation, which further influenced microglia activation. That implies may be key mediator in ischemic stroke mice modulates susceptibility to stress. This established PSA model male C57BL/6...
The aim of this study was to prepare a liposomal delivery system for rapamycin and its in vitro release characteristics. results may provide foundation the further development establishment new active treatment method targeted towards cellular components atherosclerotic plaques. ethanol injection used rapamycin‑containing liposomes. formulation optimized by orthogonal design, degree liposomes measured reverse dialysis method. Orthogonal testing showed that optimum had phospholipid...
Highlights•We designed a plectin-1 targeted dual-modality nanoparticle (Plectin-SPION-Cy7).•The nanoparticles were highly accumulated in carcinoma cells but not non-carcinoma cells.•Plectin-1 dual-functional has great potential pancreatic cancer detection.Molecular-based radiographic tests hold the promise to help precisely identifying malignant lesions and their precursors at early stages. Previous studies showed that expressed ductal adenocarcinoma tissues. In current study, we...
Artemisinin is an endoperoxide sesquiterpene lactone from Artemisia annua L with multiple beneficial effects, including anti-inflammation, antioxidant, and vascular protection. Recent studies have found that inflammation along autophagy deficiency in macrophages the possible reason for foam cell accumulation intima, which leads to atherosclerotic plaque formation. The primary aims of this study were explore inhibiting effect artemisinin on atherosclerosis high-fat diet-fed ApoE mice...
Pain relief is the major concern of patients who underwent surgery and an eternal pursuit anesthesiologist. However, postoperative pain management far beyond satisfactory although past decades has witnessed great progress in development novel analgesics analgesic techniques. Cochrane systemic review showed that patient-controlled analgesia (PCA) achieved better greater patient satisfaction compared with traditional "on-demand" parenteral analgesia, suggesting it might be manner...
Purpose: To assess the performance of combining computed tomography (CT) texture analysis with machine learning for discriminating different histopathological grades pancreatic ductal adenocarcinoma (PDAC). Methods: From July 2012 to August 2017, this retrospective study comprised 56 patients confirmed PDAC (32 men, 24 women, mean age 64.04±7.82 years) who had undergone preoperative contrast-enhanced CT imaging within 1 month before surgery. Two radiologists blinded outcome independently...
Synovitis, acne, palmoplantar pustulosis, hyperostosis and osteitis syndrome (SAPHO) is a rare that affects the skin, bones joints. Diagnosis of SAPHO established on clinical appearance imaging features. The present case report described features three cases with sternoclavicular joint arthritis but without skin manifestations using multiple modalities, including computed tomography (CT), magnetic resonance (MRI) bone scintigraphy. first was 52-year-old male who suffered from progressive for...
Small conductance calcium-activated potassium channels (SK channels) play a critical role in action potential repolarization cardiomyocytes. Recently, the anti-arrhythmic effect of metformin diabetic patients has been recognized, yet underlying mechanism remains elusive. Diabetic Goto-Kakizaki (GK) rats were untreated or treated with (300 mg/kg/day) for 12 weeks, and age-matched Wistar used as control (n = 6 per group). Electrocardiography, Hematoxylin-eosin staining Masson's trichome...
Euphorbia tirucalli is a highly drought-tolerant shrub with potential as biofuel source, which has an important ecological and economic value. The complete chloroplast genome sequence of E. was carried out using Illumina sequencing platform. 163,091 bp in total length, contained inverted repeats (IR) 26,832 separated by large single-copy (LSC) small single copy (SSC) 91,259 18,168 bp, respectively. annotation displayed 130 genes, comprising 83 protein-coding 39 tRNA eight rRNA genes. overall...
To identify genes that respond to increased nitrogen and assess the involvement of chlorophyll metabolic pathway associated regulatory mechanisms in these responses, Nitraria tangutorum seedlings were subjected four concentrations (N0, N6, N36, N60: 0, 6, 36, 60 mmol·L−1 nitrogen, respectively). The N. seedling leaf transcriptome was analyzed by high-throughput sequencing (Illumina HiSeq 4000), 332,420 transcripts 276,423 unigenes identified. numbers differentially expressed (DEGs) 4052 N0...
Drought resistance in plants is controlled by multiple genes. To identify the genes that mediate drought stress responses and to assess associated metabolic pathways desert shrub Nitraria tangutorum, we conducted a transcriptome analysis of under control (maximum field capacity) (20% maximum conditions. We analyzed differentially expressed (DEGs) N. tangutorum their enrichment KEGG database, explored molecular biological mechanisms underlying answer its tolerance. Between groups, 119...
Abstract Desert shrubs play a crucial role in controlling desertification and promoting revegetation, but drought often hinders their growth. Investigating the hydraulic strategies of desert is important order to understand adaptation predict future dynamics under climate change. In this study, we measured hydraulic-related characteristics roots, stems leaves 19 shrub species from northern China. We aimed explore coordination segmentation between different plant organs. The results were as...
Background. Kudiezi injection is a traditional Chinese medicine for acute cerebral infarction, but the exact mechanisms are poorly understood. Objective. To investigate of on inflammatory response in treatment infarction. Methods. This was prospective study patients with infarction within 48 h onset and treated between July 2012 2016 at three hospitals China. The were randomized to routine treatments (control group) versus (Kudiezi group). National Institutes Health Stroke Score assessed...
Heteroplexis Chang is an endangered genus endemic to China with important ecological and medicinal value. However, due the lack of genetic data, our conservation strategies have repeatedly been delayed by controversial phylogenetic (molecular) relationships within genera. In this study, we reported three new chloroplast (cp.) genomes (H. vernonioides, H. impressinervia microcephala) clarify between species allocated in other related Compositae.All cp. were highly conserved, showing classic...
Inverters designed using reduced active semiconductor devices can be of interest to the industry because their lower cost and enhanced reliability linked less complex gating control circuitries. Despite simplicity, most component count inverters reported date only either perform voltage-buck or boost operation with buck-boost usually attained by adding additional actively controlled dc-dc converters. Although effective, converters introduces switches, which somehow dilute advantages...