A5000921558- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Escherichia coli research studies
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Vaccine Coverage and Hesitancy
- Salmonella and Campylobacter epidemiology
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Child Nutrition and Water Access
- Essential Oils and Antimicrobial Activity
- Global Maternal and Child Health
- Pharmacological Effects of Natural Compounds
- Climate Change and Health Impacts
- Influenza Virus Research Studies
- Ginseng Biological Effects and Applications
- Hepatitis Viruses Studies and Epidemiology
- Biosensors and Analytical Detection
- Viral Infections and Outbreaks Research
- Mycobacterium research and diagnosis
- Global Public Health Policies and Epidemiology
- Cardiovascular Health and Risk Factors
University of Pretoria
2020-2024
University of Fort Hare
2018-2024
University of Washington
2024
National Health Laboratory Service
2022
National Institute for Communicable Diseases
2022
University of Cape Town
2020
University of Bolton
2010
Gastric cancer (GC) is a significant global public health problem. It the third leading cause of cancer-related mortality despite its decline in incidence since past five decades. The GC varies between regions, and this heterogeneity attributed to multi-factors, including infectious, environmental, genetic traits. Most cases are linked Helicobacter pylori (H. pylori) infection. Understanding etiology, epidemiology, risk factors necessary for prevention targeted treatment disease. In study,...
Listeria monocytogenes (L. monocytogenes) is a foodborne pathogen and the etiologic agent of listeriosis, which can be disseminated within agricultural environment particularly soil irrigation water, contaminate farm produce cause high mortality morbidity among vulnerable individuals. This study assessed incidence antibiogram L. recovered from water samples collected Chris Hani Amathole District Municipalities (DMs) in Eastern Cape Province, South Africa. The distribution presumptive was...
Prior to the 2009 pandemic H1N1, and unprecedented outbreak of Highly Pathogenic Avian Influenza (HPAI) caused by H5N1 virus, World Health Organization (WHO) called upon its Member States develop preparedness plans in response a new humans. The WHO responded this call developing national accordance with International Regulations (IHR) strengthen capabilities respond different scenarios. In study, we aim evaluate quality African region since their inception 2005. A standard checklist 61...
There is currently no approved pharmaceutical product for the treatment of COVID-19. However, antibiotics are being used management COVID-19 patients in many settings either treat to co-infections or itself. In this commentary, we highlight that increased rates antimicrobial prescribing could further worsen burden resistance (AMR). We also though AMR a global threat, Africa tends suffer most from consequences. We, therefore, call on African countries not lose sight possible implications and...
There is currently no approved pharmaceutical product for the treatment of COVID-19. However, antibiotics are being used management COVID-19 patients in many settings either treat to co-infections or itself. In this commentary, we highlight that increased rates antimicrobial prescribing could further worsen burden resistance (AMR). We also though AMR a global threat, Africa tends suffer most from consequences. We, therefore, call on African countries not lose sight possible implications and...
We assessed the prevalence of E. coli O157:H7 in irrigation water and agricultural soil samples two District Municipalities South Africa using standard culture-based molecular techniques. Presumptive counts ranged from 1.00 Log10 CFU/100 ml to 4.11 2.20 CFU/g 4.21 respectively (P ≤ 0.05). Thirteen (28%) confirmed isolates (n = 46) were Shiga toxigenic 33 (72%) toxin negative. The presence strain reported by this study suggests potential risk food safety population health.
The preharvest environment provides a suitable platform for the emergence and dissemination of multidrug resistant pathogenic bacteria. This could be detrimental to public health may lead fresh produce related disease outbreaks when transferred food web. study evaluated occurrence antibiogram fingerprints strains Escherichia coli ( E. ) recovered from irrigation water agricultural soil samples in farms Eastern Cape Province, South Africa. was isolated, pathotyped screened using standard...
This study was undertaken to evaluate the antibiogram fingerprints of some Enterobacteria recovered from irrigation water and agricultural soil in two District Municipalities Eastern Cape Province, South Africa using standard culture-based molecular methods. The prevalent resistance patterns isolates follow order: Salmonella enterica serovar Typhimurium [tetracycline (92.3%), ampicillin (69.2%)]; Enterobacter cloacae [amoxicillin/clavulanic acid (77.6%), (84.5%), cefuroxime (81.0%),...
Listeria monocytogenes (L. monocytogenes) is the etiologic agent of listeriosis which significantly affects immunocompromised individuals. The potential risk infection attributed to L. in irrigation water and agricultural soil, are key transmission pathways microbial hazards human population, was evaluated using quantitative assessment modelling. A Monte Carlo simulation with 10,000 iterations used characterize risks. High counts (mean: 11.96 × 102 CFU/100 mL; range: 0.00 56.67 mL) soil...
An uninterrupted supply of vaccines at different chain levels is a basic component functional immunization programme and care service. There can be no progress toward achieving universal health coverage sustainable development without continuous availability essential medicines in healthcare facilities. Shortages vaccines, particularly facility level an issue grave concern that requires urgent attention South Africa. The causes vaccine stock-outs are multifactorial may linked to broader...
The antibiogram signatures of E. coli O157:H7 (n=46) recovered from irrigation water and agricultural soil samples were assessed using the standard disc diffusion method against a panel 16 antibiotics molecular methods. prevalent antibiotic resistance patterns follow order: cefuroxime (95.7%), nitrofurantoin (93.5%), ampicillin (73.9%), chloramphenicol (71.7%), cefotaxime (60.9%) trimethoprim/sulfamethoxazole (58.7%). genes detected in phenotypically resistant isolates include: tetA, tetB,...
As coronavirus disease (COVID-19) cases continue to increase in Africa, healthcare workers (HCWs) have a high risk of being infected and the risks may be higher among those who work closely with patients. The HCW infections can mitigated adequate precautions within facilities, especially use personal protective equipment (PPE). We highlight contextualise findings Cochrane review on type PPE that protects best, best way put (donning) or remove (doffing) how train HCWs PPE. found low-certainty...
Freshwater sources, often used for domestic and agricultural purposes in low- middle-income countries are repositories of clinically significant bacterial pathogens. These pathogens usually diversified their antibiogram profiles posing public health threats. This study evaluated the spatial diarrhoeal disease risk diversity diarrheagenic Escherichia coli (DEC) four access points Buffalo River, Eastern Cape Province, South Africa using standard epidemiological, culture, molecular methods. The...