A5077808867- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Sesquiterpenes and Asteraceae Studies
- Autophagy in Disease and Therapy
- Salmonella and Campylobacter epidemiology
- Flavonoids in Medical Research
- Ginger and Zingiberaceae research
- Microplastics and Plastic Pollution
- Advanced Biosensing Techniques and Applications
- Tea Polyphenols and Effects
- Chromatography in Natural Products
- Toxoplasma gondii Research Studies
- Antimicrobial Peptides and Activities
- Toxin Mechanisms and Immunotoxins
- Enterobacteriaceae and Cronobacter Research
- Inflammasome and immune disorders
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and biological activity of medicinal plants
- Alkaloids: synthesis and pharmacology
- Bioactive Compounds and Antitumor Agents
- Marine Sponges and Natural Products
- Luminescence and Fluorescent Materials
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Ocular Diseases and Behçet’s Syndrome
Anhui Medical University
2021-2024
State Key Laboratory of Food Science and Technology
2018-2023
Nanchang University
2018-2023
Northwest A&F University
2023
Sichuan Agricultural University
2016-2022
Shenyang Pharmaceutical University
2017
Escherichia coli O157:H7 (E. O157:H7) has become one of the major threats to public health and food safety. However, culture method as a gold standard for detection E. requires laborious operations long processing time. Herein, we developed dual-readout aggregation-induced emission nanoparticle-based lateral flow immunoassay (LFIA) sensitive achieve qualitative quantitative assay satisfying applications under varying scenarios. 2,3-Bis(4-(bis(4-(tert-butyl)phenyl)amino)phenyl)fumaronitrile...
Ageratina adenophora is an invasive plant known for its toxicity to livestock. Current research on this has shifted from prevention the beneficial utilization of resources. This study was performed investigate effects and mechanisms cryptochlorogenic acid (CCGA) isolated inflammatory responses induced by lipopolysaccharide (LPS) in RAW264.7 cells. cells were pretreated with CCGA (200, 100, 50 μg/mL) subsequently stimulated LPS (1 16 h. The cytotoxicity tested using Cell Counting Kit (CCK8)....
Increasing evidences have demonstrated that Ageratina adenophora (A. adenophora) can cause hepatotoxicity of animals. Liver is an important site in immune regulation and inflammatory responses. However, the information about induced by A. relation to inflammation still finite. To investigate underlying mechanism, we conducted animal experiments with different dosage adenophora. Mice were randomly divided into 4 groups administrated 0%, 10%, 20% 30% levels pallet diet control, group A, B C,...
The purpose of this study was to investigate the anti-Newcastle disease virus (NDV) activities baicalin from Scutellaria baicalensis, a Traditional Chinese Medicine in vitro. Chicken embryo fibroblasts (CEFs) were infected with NDV, and quantitative analysis apoptotic cells performed using flow cytometry. Cytotoxicity anti-viral studied MTT method. results showed that maximal safe concentrations CEFs 1 × 2(-2) mg/ml. Baicalin could directly kill inhibit infectivity NDV CEF block...
Vitamin E represents a group of lipophilic phenolic compounds, including α ‐tocopherol, β γ and δ ‐tocotrienol, ‐tocotrienol isomers. Different forms vitamin have been proven to exhibit varying biological activities. However, due their structural similarities, the separation isomers is challenging task. Therefore, it crucial establish an efficient method for isolating individual In this study, co‐current countercurrent chromatography was employed isolate from commercial capsules using n...
Microcystin-leucine arginine (MCLR), a widespread environmental contaminant produced by cyanobacteria, poses severe threat to the male reproductive system. However, mechanisms of MCLR-induced testis injury accompanied autophagy are still obscure. This study aimed investigate effects MCLR on and apoptosis system its mechanism both in vitro vivo . caused damage zebrafish, resulting decreased hatching growth retardation offspring. It also remarkably enhanced autophagic flux elevating expression...
The purpose of this study was to investigate the anti-Newcastle disease virus (NDV) activities 9-oxo-10,11-dehydroageraphorone (euptox A) from Eupatorium adenophorum Spreng (E. adenophorum) in vitro. NDV infection chicken embryo fibroblasts (CEFs) performed. Cytotoxicities and antiviral euptox A assessed by MTT method. interaction with cell membrane protein detected overlay binding assay (VOPBA). expression levels genes CEFs tested RTFQ PCR. results showed that maximal safe concentrations 10...
Tea polyphenols were infused into tea seed oil in ethanol, and the ethanol was removed by vacuum distillation to prepare colloidal oil. The stability of polyphenol samples decreased with increasing added amount. Residual system detected gas chromatography (GC), yielding a concentration range 0.30 ± 0.02 1.57 0.01 g/kg, not blank. High performance liquid (HPLC) used analyze system, results proved that underwent no chemical changes after being Tyndall phenomena observed all samples. Using...
Euptox A (9-oxo-10, 11-dehydroageraphorone), the main toxin isolated from Eupatorium adenophorum, is known to induce immunotoxicity in animals. However, precise mechanism underlying effects of on splenocytes unclear. Here, we aimed investigate molecular mechanisms effect mouse spleens after its intragastric administration and found that exhibits proautophagic splenocytes. markedly arrested G0/G1 phase, which was accompanied by inhibition expression positive regulators CDK4, CDK2, cyclin D1,...
Ageratina adenophora is an invasive plant of global importance and has a broad distribution in the Western Himalayas. Endophtytic fungus Coniochaeta sp.F-8 was found adenophora. In this paper, we aim to investigate antioxidative activity cytotoxicity metabolites from sp.F-8. Consequently, two compounds Phomoxanthone A Penialidin were isolated endophytic for first time. The structures identified by IR, NMR ESI-MS methods. Moreover, both those showed considerable vitro resulted mouse embryo...
Antibodies and labels were typically non-oriented conjugated in conventional immunochromatographic assays (ICAs). In this work, a C-terminal cysteine-tagged recombinant protein A (rPA) was an oriented manner onto aggregation-induced emission fluorescence microsphere (AIEFM). The Fc fragment of anti-enrofloxacin monoclonal antibody (anti-ENR mAb) then the rPA. resulting mAb-AIEFM probe used ENR-ICA for rapid detection ENR, widely abused animal drug. with saved 66.7% anti-ENR mAb 25%...