A5000511616- Inflammatory mediators and NSAID effects
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Synthesis and biological activity
- Cardiac, Anesthesia and Surgical Outcomes
- Orthopedic Surgery and Rehabilitation
- Total Knee Arthroplasty Outcomes
- Estrogen and related hormone effects
- Orthopaedic implants and arthroplasty
- Shoulder Injury and Treatment
- Connective tissue disorders research
- Synthesis of β-Lactam Compounds
- Soft Robotics and Applications
- Click Chemistry and Applications
- Synthesis and Reactions of Organic Compounds
- Anatomy and Medical Technology
- Colorectal Cancer Surgical Treatments
- Phytochemistry and Bioactive Compounds
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Dermatological and Skeletal Disorders
- Knee injuries and reconstruction techniques
- Pulsars and Gravitational Waves Research
- Metal complexes synthesis and properties
- Abdominal Trauma and Injuries
University of Bari Aldo Moro
2010-2019
John Wiley & Sons (United States)
2016
Istituto di Farmacologia Traslazionale
2015
<b><i>Background/Aims:</i></b> Gastrointestinal damage (GD) is commonly associated with the inhibition of cyclooxygenase (COX)-1, one two known COXs, by traditional non-steroidal anti-inflammatory drugs. More recent evidences have proven that GD caused simultaneous COXs. This study was designed to evaluate effect selective COX-1 on gastric integrity. <b><i>Methods:</i></b> evaluated in male CD1 mice. Drugs were administered gavage at a dose 50...
A new set of cyclooxygenase (COX) inhibitors endowed with an additional functionality was explored. These compounds also contained either rhodamine 6G or 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, two moieties typical efflux pump substrates and inhibitors, respectively. Among all the synthesized compounds, COX opposite selectivity were discovered: compound 8...
Background: According to the literature, 95% of professional athletes return their sport after anterior cruciate ligament (ACL) reconstruction surgery.The main objective this study was verify ACL in a homogenous group amateur sportsmen and sportswomen series Italian patients. Materials methods:We designed retrospective which we analyzed sports patients operated for reconstruction.We verified whether they had returned sporting activities by comparing pre-and post-operative Tegner activity...
Pt(II)-based derivatives bearing a cyanocobalamin (CNCbl) unit were synthesized in aqueous solutions, and the reaction mixtures examined by reversed-phase liquid chromatography with electrospray ionization linear ion trap mass spectrometry (MS). Isotopic pattern analysis, multistage mass-spectra (MS/MS MS3) interpretation, differential isotopic labeling used to establish chemical composition suggest structures of products. When cisplatin (cis-[PtCl2(NH3)2]) was as Pt(II) drug derivative,...