A5020869854- Artificial Intelligence in Healthcare and Education
- Machine Learning in Healthcare
- Glioma Diagnosis and Treatment
- Medical Coding and Health Information
- Topic Modeling
- Ophthalmology and Visual Health Research
- Telomeres, Telomerase, and Senescence
- Non-Invasive Vital Sign Monitoring
- Social Media in Health Education
- Ophthalmology and Visual Impairment Studies
- Advanced Sensor and Energy Harvesting Materials
- Pancreatitis Pathology and Treatment
- Neuroblastoma Research and Treatments
- Chromatin Remodeling and Cancer
- Liver Disease Diagnosis and Treatment
- Erythropoietin and Anemia Treatment
- Microtubule and mitosis dynamics
- RNA Interference and Gene Delivery
- Cellular Mechanics and Interactions
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
- Blood properties and coagulation
- Electrical and Bioimpedance Tomography
- Gene expression and cancer classification
- Lipid metabolism and disorders
Beijing Academy of Artificial Intelligence
2023-2024
Shanghai Artificial Intelligence Laboratory
2023-2024
Chinese University of Hong Kong
1988-2017
Anhui Provincial Hospital
2000
China Medical University
2000
West China Medical Center of Sichuan University
2000
Beijing Hospital
2000
Patients with nonalcoholic steatohepatitis (NASH) have gut dysbiosis and intestinal bacterial overgrowth.To test the hypothesis that endotoxemia is associated histological severity of fatty liver disease (NAFLD) determine factors endotoxemia.The markers lipopolysaccharide-binding protein (LBP) endotoxin levels were measured in 237 NAFLD patients 1 day before biopsy. Biomarkers injury transient elastography performed as additional severity.A total 114/237 (48%) had NASH 80/237 (34%) F2-4...
Large language models (LLMs) have achieved great progress in natural processing tasks and demonstrated the potential for use clinical applications. Despite their capabilities, LLMs medical domain are prone to generating hallucinations (not fully reliable responses). Hallucinations LLMs' responses create substantial risks, potentially threatening patients' physical safety. Thus, perceive prevent this safety risk, it is essential evaluate build a systematic evaluation.
CD44 is a molecular marker associated with cancer stem cell populations and treatment resistance in glioma. More effective therapies will result from approaches aimed at targeting glioma cells high CD44. Glioma-initiating lines were derived fresh surgical glioblastoma samples. Expression of tissue transglutaminase 2 (TGM2) was attenuated through lentivirus-mediated short hairpin RNA knockdown. MTT assay [(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] used to evaluate the...
IMPORTANCE Identifying pediatric eye diseases at an early stage is a worldwide issue. Traditional screening procedures depend on hospitals and ophthalmologists, which are expensive time-consuming. Using artificial intelligence (AI) to assess children’s conditions from mobile photographs could facilitate convenient identification of disorders in home setting. OBJECTIVE To develop AI model identify myopia, strabismus, ptosis using photographs. DESIGN, SETTING, AND PARTICIPANTS This...
Aims: While it is well known that pilocytic astrocytomas are clinically distinct from diffuse astrocytomas, few comprehensive studies have focused on their genetic differences. The aim of this study was to examine for alterations commonly seen in astrocytomas. Methods and results : By using molecular immunohistochemical techniques, we evaluated p16 , p53 CDK4 PTEN genes 29 Mutation screening performed by single strand conformation polymorphism analysis followed direct sequencing. Loss...
Central neurocytoma is a rare central nervous system tumour typically found in the lateral ventricles and at septum pellucidum. Histologically, it resembles oligodendrogliomas yet ultrastructurally, shows neuronal differentiation. Its molecular oncogenesis not known. The aim of this study was to examine whether major genetic events tumours, namely allelic deletions chromosomes 1p 19q N-myc amplification, can be neurocytomas. As there one report describing gain chromosome 7 neurocytomas, we...
Although new technologies have increased the efficiency and convenience of medical care, patients still struggle to identify specialized outpatient departments in Chinese tertiary hospitals due a lack knowledge.
The availability of high-throughput sequencing data creates opportunities to comprehensively understand human diseases as well challenges train machine learning models using such high dimensions data. Here, we propose a denoised multi-omics integration framework, which contains distribution-based feature denoising algorithm, Feature Selection with Distribution (FSD), for dimension reduction and Attention Multi-Omics Integration (AttentionMOI) predict cancer prognosis identify subtypes. We...
METHODS: First, a set of evaluation criteria is designed based on comprehensive literature review. Second, existing candidate are optimized for using Delphi method by five experts in medicine and engineering. Third, three clinical design medical datasets to interact with LLMs. Finally, benchmarking experiments conducted the datasets. The responses generated chatbots LLMs recorded blind evaluations licensed experts. RESULTS: obtained cover professional capabilities, social contextual...
Epidermal growth factor receptor is overexpressed and/or amplified in up to 50% of glioblastomas, suggesting an important role this gene glial tumorigenesis and progression. In the present study we demonstrated that epidermal involved regulation telomerase activity glioblastoma. Antisense-epidermal approach was used inhibit expression glioblastoma U87MG cells. Telomerase antisense-epidermal cells decreased by 54 folds compared with control Moreover, telomere lengths were shortened. addition,...
The use of electrical impedance pneumography (EIP) and respiratory inductive plethysmography (RIP) for noninvasive ventilatory measurements during incremental cycle-ergometer stress testing was evaluated. In three normal subjects two overweight tidal volume as determined by either technique linearly related to that resulting from a conventional pneumotachograph rest maximal exercise. the group, values obtained EIP exhibited considerable variability, mainly result increased motion artifacts....
There is an increasing interest in developing LLMs for medical diagnosis to improve efficiency. Despite their alluring technological potential, there no unified and comprehensive evaluation criterion, leading the inability evaluate quality potential risks of LLMs, further hindering application treatment scenarios. Besides, current evaluations heavily rely on labor-intensive interactions with obtain diagnostic dialogues human dialogue. To tackle lack we first initially establish termed...
Background: Although new technologies have increased the efficiency and convenience of medical care, patients still struggle to identify specialized outpatient departments in Chinese tertiary hospitals due a lack knowledge. Thereby, we aimed develop precise subdividable triage system improve experiences patient care.Methods: We collected 395,790 EMRs 500 dialogue groups. 387,876 (98%) each dataset was used design train model, 3,957 (1%) for testing validation. The evaluated by recommendation...
<sec> <title>BACKGROUND</title> Although new technologies have increased the efficiency and convenience of medical care, patients still struggle to identify specialized outpatient departments in Chinese tertiary hospitals due a lack knowledge. </sec> <title>OBJECTIVE</title> The objective our study was develop precise subdividable triage system improve experiences patient care. <title>METHODS</title> We collected 395,790 electronic records (EMRs) 500 dialogue groups. EMRs were divided into 3...