Gnanabhaskar Danaboina

ORCID: 0000-0001-5765-2366
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About
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Research Areas
  • Phytochemistry and biological activity of medicinal plants
  • Medicinal Plants and Neuroprotection
  • Synthesis of Organic Compounds
  • Piperaceae Chemical and Biological Studies
  • Natural Antidiabetic Agents Studies
  • Ginseng Biological Effects and Applications
  • Herbal Medicine Research Studies
  • Bioactive natural compounds
  • Psidium guajava Extracts and Applications
  • Natural product bioactivities and synthesis
  • Phytochemistry and Biological Activities
  • Analytical Chemistry and Chromatography
  • Phytochemicals and Medicinal Plants
  • Pharmacological Effects of Natural Compounds
  • Traditional Chinese Medicine Analysis

Central Council for Research in Ayurvedic Science
2025

Ministry of AYUSH
2023

Government of India
2023

Ministry of Health and Family Welfare
2023

Aegle marmelos (L.) Correa is an Indian medicinal plant known for its vast therapeutic activities. In Ayurveda, the to balance "vata," "pitta," and "kapha" dosh. Recent studies suggest anti-inflammatory, anti-microbial, anti-diabetic potential but lack in defining dosage over This study aims determine chemical profile of fruit extract; identification, enrichment, characterization principal active component(s) having anti-inflammatory potential. Targeted enrichment total coumarins, focusing...

10.1016/j.jsps.2023.101708 article EN cc-by Saudi Pharmaceutical Journal 2023-07-25

Abstract The acute pathogenesis with rapid inflammation enhances the intertrabecular spaces which refers to an increase in intraocular pressure (IOP) uveitic glaucoma. Boerhaavia diffusa ( B. ) plant root contains boeravinone A–J, a class of rotenoids exhibiting hepatoprotective, immunomodulatory, and anti‐inflammatory actions. This article reports comparative silico Rho‐kinase inhibition FP‐agonists study these rotenoids. ADMET reflects suitability terms drug‐likeness, human intestinal...

10.1002/slct.202404950 article EN ChemistrySelect 2025-03-01

Phytopharmaceutical Ingredients (PPI) are separate class of drugs, governing the purified fractions medicinal plant part with minimum four bioactive compounds attributing pharmacological and therapeutic activities. In this context, we have conducted a research study on Glycyrrhiza glabra roots, to prepare its PPI monograph. The aforementioned has been pursued for anti-diabetic potential, basis preliminary results, extract enrichment was done detect quantify markers viz., liquiritin,...

10.1016/j.cjac.2023.100247 article EN cc-by-nc-nd CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION) 2023-03-05

The acute pathogenesis with rapid inflammation enhances the intertrabecular spaces which refers to an increase in IOP uvetic glaucoma. Boerhaavia diffusa plant root contains boeravinones A–J is estimated by LC-MS/MS analysis. These compounds belong a class of rotenoids, exhibit hepatoprotective, immunomodulatory and anti-inflammatory actions. This article reports comparative in-silico Rho kinase inhibition FP-agonists study these rotenoids. ADMET reflects suitability rotenoids terms...

10.2139/ssrn.4800680 preprint EN 2024-01-01

Abstract The existing HPLC methods for the assaying of multiple markers in standardized herbal extracts use a single wavelength quantification, which usually leads to lower assay than actual claims. It was because screening phytochemical standards irrespective their absorption maxima drive decrease peak are response ultimately impact assay. To overcome this issue, we have applied methodology, called Mixed Standard Multi-Signal (MSMS) simultaneous detection, where reference get extracted each...

10.1186/s43094-023-00555-4 article EN cc-by Future Journal of Pharmaceutical Sciences 2023-11-13
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