A5079371357- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Atomic and Subatomic Physics Research
- Advanced NMR Techniques and Applications
- Renal and Vascular Pathologies
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Nutrition and Health in Aging
- Cardiac Imaging and Diagnostics
- Advanced Neuroimaging Techniques and Applications
- Cancer Genomics and Diagnostics
- Prostate Cancer Treatment and Research
- Cerebrovascular and Carotid Artery Diseases
- Body Composition Measurement Techniques
- Dialysis and Renal Disease Management
- Urologic and reproductive health conditions
- Peripheral Artery Disease Management
- AI in cancer detection
- Pediatric Urology and Nephrology Studies
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- Colorectal Cancer Treatments and Studies
University of Utah
2015-2025
Huntsman Cancer Institute
2012-2021
Advanced Imaging Research (United States)
2008-2019
Suburban Hospital
2000-2001
Stanford University
1994-1997
Resonance Research (United States)
1994
KU Leuven
1994
Delft University of Technology
1994
Lung Institute
1994
Objective . Intramuscular adipose tissue (IMAT) and sarcopenia may adversely impact mobility function physical activity. This study determined the association of locomotor muscle structure with in older adults. Method 109 adults a variety comorbid disease conditions were examined for thigh composition via MRI, knee extensor strength isometric dynamometry, function. The contribution strength, quadriceps lean tissue, IMAT to explaining variability was using multivariate linear regression...
Abstract A radiofrequency (RF) excitation scheme is presented in which flip angle encoded the phase of resulting excitation. This implemented with nonselective hard pulses, and used to give maps over three‐dimensional volumes. phase‐sensitive B1 mapping can be combined various acquisition methods such as gradient recalled echo (GRE) echo‐planar (EP) readouts. Imaging time depends primarily on readout method, roughly equivalent imaging conventional double‐angle techniques for acquisition. The...
The purpose of this study was to compare the outcomes between a diabetes exercise training program using combined aerobic and high-force eccentric resistance only.
Propagation of errors, in conjunction with the theoretical signal equation for spoiled gradient echo pulse sequences, is used to derive a expression uncertainty quantitative variable flip angle T(1) mapping using two angles. This then minimized rigorous optimal angles that elucidates commonly empirical result. The expressions and are combined lower bound on achievable given set sequence parameters signal-to-noise ratio (SNR). These results provide means quantitatively determining effect...
Background and objectives Modifiable factors, such as body size composition, could influence physical function quality of life in patients undergoing maintenance hemodialysis (MHD). Design, setting, participants, & measurements From January 2008 to June 2012, mass index (BMI), waist circumference (WC), magnetic resonance imaging midthigh muscle area (MTMA) intra-abdominal fat (IAFA) were obtained at baseline 105 MHD patients. Six-minute walk distances mental component scores (PCS MCS) from...
Blood oxygen level-dependent (BOLD) MRI data of kidney, while indicative tissue oxygenation level (Po2), is in fact influenced by multiple confounding factors, such as R2, perfusion, permeability, and hematocrit. We aim to explore the feasibility extracting Po2 from renal BOLD data. A method two steps was proposed: first, a Monte Carlo simulation estimate blood saturation (SHb) signals, second, an transit model convert SHb Po2. The proposed calibrated validated with 20 pigs (12 before after...
Abstract Dynamic shimming has been implemented in three pulse sequences on a commercial GE Signa 1.5‐T imaging system. Multi‐slice field maps are acquired before the sequence, and linear shim terms center frequencies calculated for each slice. During scan, frequency set sequence repetition according to current Acquisition of multi‐slice calculation slice accomplished matter seconds. Pulse require only minimal modification add dynamic capability. Results shown fat saturation spin‐echo...
Several methods of flip angle mapping for magnetic resonance imaging have been proposed. We evaluated the accuracy five measurement in presence noise. Our analysis was performed a closed form by propagation probability density functions (PDFs). The compared were (1) phase-sensitive method, (2) dual-angle method using gradient recalled echoes (GRE), (3) an extended version GRE incorporating phase information, (4) AFI and (5) information. took into account differences required time these...
Abstract Purpose: To prospectively investigate whether a rapid dynamic MRI protocol, in conjunction with pharmacokinetic modeling, could provide diagnostically useful information for discriminating biopsy‐proven benign lesions from malignancies. Materials and Methods: Patients referred to breast biopsy based on suspicious screening findings were eligible. After anatomic imaging, patients scanned using protocol complete bilateral coverage. Maps of parameters representing transfer constant ( K...
The purpose of this study was to design and prepare macromolecular contrast agents (CAs) with a precisely defined globular structure for MR angiography tumor angiogenesis imaging. Generations 1 through 3 (Gd-DOTA-monoamide)-poly-l-lysine octasilsesquioxane dendrimers were prepared as nanoglobular MRI CAs. Gd(III) chelates had well-defined compact high loading Gd-DOTA-monoamide at their surface. size the G1, G2, G3 CAs approximately 2.0, 2.4, 3.2 nm, respectively. T1 relaxivity 6.4, 7.2, 10.0...
Purpose The objective of this study was to determine whether a sodium phased array would improve breast MRI at 3 T. secondary create acceptable proton images with the in place. Methods A novel composite for combined proton/sodium T is compared coil single and channel. consists 7‐channel receive array, larger transmit coil, 4‐channel transceive array. new design utilizes smaller loops than typically used imaging, uses decoupling methods between loops, multichannel coil. reduces coupling...
Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention if a greater reduction in IMAT eccentric versus traditional resistance training. Seventy-seven older adults (age 75.5 ± 6.8) multiple comorbidities history of falling completed three-month paired either or MRI the mid-thigh examined at three time points changes...
Abstract Quantitative sodium MRI requires accurate knowledge of factors affecting the signal. One important determinant signal level is transmit B 1 field strength. However, low signal‐to‐noise ratio typical makes mapping in reasonable scan times challenging. A new phase‐sensitive technique has recently been shown to work better than widely used dual‐angle method low‐signal‐to‐noise situations and over a broader range flip angles. In this work, applied sodium, its performance compared...
The purpose of this work was to synchronously acquire proton (1H) and sodium (23Na) image data on a 3T clinical MRI system within the same sequence, without internal modification hardware, demonstrate synchronous acquisition with 1H/23Na-GRE imaging Cartesian radial k-space sampling. Synchronous dual-nuclear implemented by: mixing down 1H signal so that both 23Na were acquired at frequency by conventional system; interleaving 1H/23Na transmit pulses in sequences; using phase stabilization...
Abstract A method of three‐dimensional spectral‐spatial excitation is presented which selective simultaneously in two spatial dimensions and the spectral or chemical shift dimension. This can be used to create passbands whose center frequency varies as a function location within an imaging plane. variation passband may specified by acquired main field (B 0 ) map; resulting excitations compensate for inhomogeneity B field. In vivo images are allows water‐only presence large where conventional...