A5039543012- Visual Attention and Saliency Detection
- Planarian Biology and Electrostimulation
- Physiological and biochemical adaptations
- Cell Image Analysis Techniques
- Single-cell and spatial transcriptomics
- Advanced Fluorescence Microscopy Techniques
- 3D Printing in Biomedical Research
- Silk-based biomaterials and applications
- Neurobiology and Insect Physiology Research
- Cellular Mechanics and Interactions
Lawrence Livermore National Laboratory
2024
RIKEN Center for Biosystems Dynamics Research
2019-2020
King's College London
2015-2016
University of Oxford
2015
Activation is an essential process that accompanies fertilisation in all animals and heralds major cellular changes, most notably, resumption of the cell cycle. While activation involves wave-like oscillations intracellular Ca2+ concentration mammals, ascidians polychaete worms a single peak fish frogs, insects, such as Drosophila, to date, it has not been shown what changes levels occur. Here, we utilise ratiometric imaging indicator dyes genetically encoded proteins identify characterise...
Contemporary state-of-the-art video object segmentation (VOS) models compare incoming unannotated images to a history of image-mask relations via affinity or cross-attention predict masks. We refer the internal memory state initial pair and past image-masks as working buffer. While current art perform very well on clean data, their reliance previous frames leaves room for error. Affinity-based algorithms include inductive bias that there is temporal continuity between consecutive frames. To...
Morphological constancy is universal in developing systems. It unclear whether precise morphogenesis stems from faithful mechanical interpretation of gene expression patterns. We investigate the formation cephalic furrow, an epithelial fold that precisely positioned with a linear morphology. Fold initiation specified by genetic code single-cell row resolution. This positional activates and spatially confines lateral myosin contractility to induce folding. However, 20% initiating cells are...