Samar J. Almehmadi

ORCID: 0000-0001-5848-9679
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About
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Research Areas
  • Conducting polymers and applications
  • Synthesis and biological activity
  • Synthesis and Characterization of Heterocyclic Compounds
  • Antimicrobial agents and applications
  • Polymer Nanocomposite Synthesis and Irradiation
  • Dielectric materials and actuators
  • Synthesis and Biological Evaluation
  • biodegradable polymer synthesis and properties
  • Quinazolinone synthesis and applications
  • Metal complexes synthesis and properties
  • Gas Sensing Nanomaterials and Sensors
  • Inorganic and Organometallic Chemistry
  • Synthesis and properties of polymers
  • Advanced Polymer Synthesis and Characterization
  • Liquid Crystal Research Advancements
  • Natural Compounds in Disease Treatment
  • PI3K/AKT/mTOR signaling in cancer
  • Laser-Ablation Synthesis of Nanoparticles
  • Advanced Breast Cancer Therapies
  • Organometallic Compounds Synthesis and Characterization
  • Silicone and Siloxane Chemistry
  • ZnO doping and properties
  • Photochromic and Fluorescence Chemistry
  • Supramolecular Self-Assembly in Materials
  • Transition Metal Oxide Nanomaterials

Umm al-Qura University
2021-2024

King Abdulaziz University
2020

Nanocomposites based on polyethylene oxide (PEO)/Sodium Alginate (NaAlg) with varying content of tungsten trioxide nanoparticles (WO3 NPs) have been synthesized by using a green solvent casting method. Through the use X-ray diffraction (XRD), Fourier transforms infrared (FTIR), and Ultraviolet–visible spectroscopy (UV-Vis.), interaction mixed components has evaluated. Studies shown that WO3 blend's component parts interact strongly at their interfaces. XRD confirms increasing amorphous...

10.1016/j.jmrt.2023.08.044 article EN cc-by-nc-nd Journal of Materials Research and Technology 2023-08-10

Abstract In this study, novel flexible polymer nanocomposite films formed of polyvinyl alcohol (PVA), sodium alginate (NaAlg), titanium dioxide (TiO2) and graphene oxide (GO) as nanofiller are fabricated by using casting method. The PVA/NaAlg‐GO/TiO 2 characterized various techniques. synergistic effects GO/TiO on the electrical, dielectric properties, energy density efficiency PVA/NaAlg blend have been investigated in range frequency from 10 Hz to 7 MHz. XRD data showed that intensity...

10.1002/pat.6105 article EN Polymers for Advanced Technologies 2023-05-30

Abstract Simple preparation of flame‐retardant, photoluminescent, and superhydrophobic smart nanocomposite coating was developed applied onto cotton fibres using the simple pad–dry–cure technique. This novel strategy involved immobilization rare‐earth‐doped aluminium strontium oxide (ASO; SrAl 2 O 4 :Eu +2 ,Dy +3 ) nanoparticles, environmentally friendly room temperature vulcanizing silicone rubber (RTV) Exolet AP422 (Ex). The fabrics were also able to produce a char film in fire‐resistant...

10.1002/bio.4123 article EN Luminescence 2021-07-26

The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, 41 chosen for synthesis based on results in silico screening. Each synthesized was tested its vitro antibacterial antifungal activities a variety strains. All showed...

10.3390/molecules28020501 article EN cc-by Molecules 2023-01-04

The automobile vehicles must be operated on fuel containing no more than 10% ethanol. Use of having ethanol may cause engine malfunction, starting and running issues, material degradation. These negative impacts could irreversible damage to the vehicles. Therefore, mixing in petrol should controlled below level. current work is first report sensing with reference variation DC electrical conductivity polythiophene/graphitic-carbon nitride (PTh/gC3N4) nanocomposite. situ chemical oxidative...

10.1039/d3ra00381g article EN cc-by RSC Advances 2023-01-01

A new series of polyurea derivatives and its nanocomposites were synthesised by the solution polycondensation method through interaction between 4(2-aminothiazol-4-ylbenzylidene)-4-(tert-butyl) cyclohexanone diisocyanate compound in pyridine. The PU1–3 structure was confirmed using Fourier transform-infrared (FTIR) spectroscopy characterised solubility, viscometry, gel permeation chromatography (GPC), X-ray diffraction (XRD) analysis. In addition, evaluated TGA. Polyurea–TiO2nanocomposites...

10.1080/15685551.2020.1767490 article EN cc-by Designed Monomers & Polymers 2020-01-01

Aim: Thalidomide, a once notorious sedative, is now clinically used as an antitumor agent. We aimed to use it lead compound for designing pyrimidine-phthalimide hybrids. Materials & methods: Nucleophilic substitution reaction of thalidomide analog 4 with primary and/or secondary aliphatic amines afforded hybrids 5a-g, 6 and 7a-d. Results conclusion: Compound 7c showed high antiproliferative activity against four cell lines: HepG-2 (IC50: 7.86 ± 0.5 μM), MCF-7 2.77 0.1 HCT-116 5.73 0.4 μM)...

10.4155/fmc-2023-0025 article EN Future Medicinal Chemistry 2023-04-01

Through a two-step procedure, 3-amino-7-chloro-2-methylquinazolin-4(3H)-one was synthesized from 2-amino-4-chlorobenzoic acid as starting material. The latter reacted with chloro acetylchloride, then nucleophilically substituted various secondary amines to produce acetamide derivatives (5a-e), or underwent condensation reaction aldehydes arylidine (6a-e). In-silico study of drug-likeness and ADME descriptors conducted for all compounds. Compounds showed good oral bioavailability, well...

10.1016/j.arabjc.2021.103614 article EN cc-by-nc-nd Arabian Journal of Chemistry 2021-12-09

Abstract The application of Friedel-Craft reactions has been extended to the biological systems. Recently, these have led generation a new set polyketones (PK a-c ) along with related zinc oxide doped nanocomposites (ZnOPK d-f ). Prior process polymerization, newly synthesized monomers were subjected spectral analysis reveal their chemical structures. Three arylidene based on three different moieties including benzylidene, thiophenylidene and furfurylidene through direct condensation...

10.1088/2053-1591/aba0e8 article EN Materials Research Express 2020-06-29

Khalid A. Alamrya, Samar J. Almehmadia, M.A. Elfakyb, H. F. Al-Shareefc, Samah A.d & Mahmoud Husseinae* a Department of Chemistry, Faculty Science, King Abdulaziz University, Jeddah, Saudi Arabiab Pharmacy, Natural Products and Alternative Medicine Department, Arabiac Departement Applied Umm Al-Qura Makkah, Arabiad Biochemistry, Medical Sciences, Arabiae Polymer Chemistry Lab., Assiut Assiut, Egypt

10.1080/25740881.2020.1784213 article EN Polymer-Plastics Technology and Materials 2020-06-30
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