A5014479649- Optical Imaging and Spectroscopy Techniques
- Spectroscopy Techniques in Biomedical and Chemical Research
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Photodynamic Therapy Research Studies
- Infrared Thermography in Medicine
- Ocular and Laser Science Research
- Spectroscopy and Chemometric Analyses
- Advanced Vision and Imaging
- Bladder and Urothelial Cancer Treatments
- Chaos-based Image/Signal Encryption
- Colorectal Cancer Screening and Detection
- Medical Image Segmentation Techniques
- Advanced Fluorescence Microscopy Techniques
- Skin Protection and Aging
- Advanced Image and Video Retrieval Techniques
- Optical measurement and interference techniques
- Cutaneous Melanoma Detection and Management
- 3D Shape Modeling and Analysis
- Advanced Steganography and Watermarking Techniques
- Robotics and Sensor-Based Localization
- Connexins and lens biology
- Non-Invasive Vital Sign Monitoring
- Elasticity and Material Modeling
- Dermatologic Treatments and Research
Université de Lorraine
2016-2025
Centre National de la Recherche Scientifique
2015-2025
Centre de Recherche en Automatique de Nancy
2015-2024
Délégation Centre-Est
2015
International Society for Optics and Photonics
2015
Optica
2015
Institut National Polytechnique de Lorraine
2004-2009
Centre National pour la Recherche Scientifique et Technique (CNRST)
2008
Institut National Polytechnique de Toulouse
2004
Laboratoire Énergies et Mécanique Théorique et Appliquée
1999-2003
Abstract We present a comprehensive analysis of the submissions to first edition Endoscopy Artefact Detection challenge (EAD). Using crowd-sourcing, this initiative is step towards understanding limitations existing state-of-the-art computer vision methods applied endoscopy and promoting development new approaches suitable for clinical translation. routine imaging technique detection, diagnosis treatment diseases in hollow-organs; esophagus, stomach, colon, uterus bladder. However nature...
Cancers located on the internal wall of bladders can be detected in image sequences acquired with endoscopes. The clinical diagnosis and follow-up facilitated by building a unique panoramic bladder images from different viewpoints. This process, called mosaicing, consists two steps. In first step, consecutive are pairwise registered to find local transformation matrices linking geometrically images. second all placed common global coordinate system. this contribution, mutual...
Optical spectroscopy is studied to contribute skin cancer diagnosis. Indeed, optical spectra are modified along progression and provide complementary information (e.g., on metabolism tissue structure) clinical examination for surgical guidance [1,2]. The current original dataset made of autofluorescence diffuse reflectance acquired in vivo 131 patients' with the SpectroLive device [3,4]. Spatially-resolved measurements were performed using a multi-fiber optic probe featuring 4 distances...
The incidence of keratinocyte carcinomas (KCs) is increasing every year, making the task developing new methods for KC early diagnosis utmost medical and economical importance. We aim to evaluate diagnostic aid performance an optical spectroscopy device associated with a machine-learning classification method. present autofluorescence diffuse reflectance spectra obtained in vivo from 131 patients on four histological classes: basal cell carcinoma (BCC), squamous (SCC), actinic keratosis...
Abstract Gap junctions play an important role in vital functions, including the regulation of cell growth and differentiation. Connexins 43 (Cx43) are most widely expressed gap junction proteins. Cellular localization phosphorylated Cx43 has been implicated capacity junctional intercellular communication (GJIC). To follow functionality GJIC different types, monolayer cultures, characterized by patterns Cx43, we used a fluorescence recovery after photobleaching (FRAP) technique, compared two...
SignificanceThe clinical use of optical methods for in vivo skin imaging is limited by strong scattering properties, which reduce image contrast and probing depth. The efficiency can be improved clearing (OC). However, the OC agents (OCAs) a setting, compliance with acceptable non-toxic concentrations required.AimOC human skin, combined physical chemical to enhance permeability OCAs, was performed determine clearing-effectiveness biocompatible OCAs using line-field confocal coherence...
Endoscopic artifacts are a core challenge in facilitating the diagnosis and treatment of diseases hollow organs. Precise detection specific like pixel saturations, motion blur, specular reflections, bubbles debris is essential for high-quality frame restoration crucial realizing reliable computer-assisted tools improved patient care. At present most videos endoscopy currently not analyzed due to abundant presence multi-class video frames. Through endoscopic artifact (EAD 2019) challenge, we...
Background: Keloids and hypertrophic scars (HSc) affect 4.5–16% of the population. Thus far, different approaches keloid treatment are not very efficient, with a 50% relapse rate many ongoing researches looking for simple, safe more efficient therapeutic methods. Tacrolimus is an immunomodulator that could be useful in treating keloid. Objectives: The objective this study to evaluate effectiveness inhibiting HSc formation on rabbits' ears model check optical skin spectroscopy tissue...
Histopathological analysis and in vivo optical spectroscopy were used to discriminate several histological stages of UV-irradiated mouse skin. At different times throughout the 30-week irradiation, autofluorescence (AF) diffuse reflectance (DR) spectra acquired a bimodal approach. Then skin was sampled processed be classified, according morphological criteria, into four categories: normal, three types hyperplasia (compensatory, atypical, dysplastic). After extracting spectral...
This paper deals with multi-class classification of skin pre-cancerous stages based on bimodal spectroscopic features combining spatially resolved AutoFluorescence (AF) and Diffuse Reflectance (DR) measurements. A new hybrid method to extract select is presented. It Discrete Cosine Transform (DCT) applied AF spectra Mutual Information (MI) DR spectra. The performed by means a SVM: the M-SVM2. Its performance compared one One-Versus-All (OVA) decomposition involving bi-class SVMs as base...
This contribution presents the development of an optical spectroscopy device, called SpectroLive, that allows spatially-resolved multiply-excited autofluorescence and diffuse reflectance measurements. Besides describing this study aims at presenting metrological safety regulation validations performed towards its aimed application to skin carcinoma in vivo diagnosis. device is made six light sources four spectrometers for detection back-scattered intensity spectra collected through probe...
This paper describes an experimental study combining spatially resolved autofluorescence (AF) and diffuse reflectance (DR) fibred spectroscopies to discriminate in vivo between healthy pathological tissues a preclinical model of bladder cancer. Then, detailed step-by-step analysis scheme is presented for the extraction selection discriminative spectral features (correlation, linear discriminant, logistic regression analysis), spectroscopic data final classification algorithms (regularized...