A5078059309- Astrophysical Phenomena and Observations
- Pulsars and Gravitational Waves Research
- Astrophysics and Cosmic Phenomena
- Mechanics and Biomechanics Studies
- Gamma-ray bursts and supernovae
- Bacteriophages and microbial interactions
- Asthma and respiratory diseases
- SARS-CoV-2 and COVID-19 Research
- Allergic Rhinitis and Sensitization
- High-pressure geophysics and materials
- Advanced X-ray Imaging Techniques
- Genomics and Phylogenetic Studies
- Infrared Thermography in Medicine
- Natural Antidiabetic Agents Studies
- COVID-19 epidemiological studies
- Cancer Research and Treatments
- Olfactory and Sensory Function Studies
- Heat Transfer Mechanisms
- Microbial infections and disease research
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Viral gastroenteritis research and epidemiology
- Galaxies: Formation, Evolution, Phenomena
- Medical Imaging Techniques and Applications
- Animal Virus Infections Studies
University of Tübingen
2024-2025
Fudan University
2018-2024
Zhongshan Hospital
2024
Institute of Microbiology
2023-2024
Chinese Academy of Sciences
1999-2024
Hefei University of Technology
2018-2024
Wuhan University
2023-2024
Zhongnan Hospital of Wuhan University
2024
Xiangya Hospital Central South University
2021-2024
Central South University
2016-2024
With the widespread vaccinations against coronavirus disease 2019 (COVID-19), we are witnessing gradually waning neutralizing antibodies and increasing cases of breakthrough infections, necessitating development drugs aside from vaccines, particularly ones that can be administered outside hospitals. Here, present two cross-reactive nanobodies (R14 S43) their multivalent derivatives, including decameric (fused to immunoglobulin M [IgM] Fc) maintain potent activity severe acute respiratory...
Abstract Einstein’s theory of General Relativity predicts that the spacetime metric around astrophysical black holes is described by Kerr solution. In this work, we employ state-of-the-art relativistic reflection modeling to analyze a selected set NuSTAR spectra Galactic obtain most robust and precise constraints on hole hypothesis possible today. Our are much more stringent than those from other electromagnetic techniques and, with some sources, find stronger currently available gravitational waves.
The ideal photodynamic therapy (PDT) should effectively remove the primary tumor, and produce a stronger immune memory effect to inhibit tumor recurrence metastasis. However, limited by hypoxic immunosuppressive microenvironment, PDT efficiency is apparently low. Here, Chlorella (Chl.) exploited enhance local producing oxygen reverse hypoxia, release adjuvants microenvironment abscopal afterwards. Results from different animal models indicated that Chl. could related response. Ultimately,...
The continuum-fitting and the iron-line methods are currently two leading techniques for measuring spins of accreting black holes. In past few years, these have been developed testing fundamental physics. present work, we employ state-of-the-art models to test holes through analyze three NuSTAR observations hole binary GRS 1716-249 during its outburst in 2016-2017. observations, source was a hard-intermediate state spectra show both strong thermal component prominent relativistic reflection...
Abstract We present an analysis of the relativistic reflection spectra GX 339–4 during hard-to-soft transition its 2021 outburst observed by Insight–HXMT. The strong signatures in data suggest a high black hole spin ( * > 0.86) and intermediate disk inclination angle i ≈ 35°–43°) system. is accompanied increasing temperature softening corona emission, while inner radius remains stable. Assuming lamppost geometry, height also found to stay close across state transition. If we include...
Abstract We present a new model to calculate reflection spectra of thin accretion disks in Kerr spacetimes. Our includes the effect returning radiation, which is radiation that emitted by disk and returns because strong light bending near black hole. The major improvement with respect existing models it calculates spectrum at every point on using actual incident radiation. Assuming lamppost coronal geometry, we simulate simultaneous observations NICER NuSTAR bright Galactic holes fit...
The effect of the returning radiation has long been ignored in analysis reflection spectra Galactic black holes and active galactic nuclei only recently implemented relxill package. Here we present a study on impact estimate parameters holes. We consider high-quality NuSTAR three (GX 339-4, Swift J1658.2-4242, MAXI J1535-571) fit data with lamppost model latest version relxill, first without including then radiation. do not find any significant difference these systems between two cases,...
The effect of the returning radiation has long been ignored in analysis reflection spectra Galactic black holes and active galactic nuclei only recently implemented package. Here we present a study on impact estimate parameters holes. We consider high-quality three (GX 339–4, Swift J1658.2–4242, MAXI J1535–571) fit data with lamppost model latest version , first without including then radiation. do not find any significant difference these systems between two cases, even if all sources are...
Abstract Narrow-line Seyfert 1 AGNs (NLS1s) represent a unique stage in the black hole growth history, characterised by low masses of approximately 106–108 solar and around-Eddington accretion rates. X-ray studies NLS1s have largely been confined to local Universe (z < 0.2), while their broad-line counterparts radio-loud quasars more extensively investigated at higher redshifts. In this work, we conducted an spectral analysis for 14 SDSS-observed z ≈ eRASS1 catalogue. We found that...
Abstract The production of oxygen by photosynthetic microorganisms (PSMs) has recently attracted interest concerning the in vivo treatment multiple diseases for their vivo, since PSMs have good biological safety. Here, first evidence that can be used as a photothermal source to perform biophotothermal therapy (bio‐PTT) is provided. In vitro and experiments proved generate heat direct elimination tumors release series pathogen‐associated molecular patterns adjuvants immune stimulation under...
The continuum-fitting and the iron line methods are currently two leading techniques for probing strong gravity region around accreting black holes. In present work, we test Kerr hole hypothesis with stellar-mass in GRS 1915+105 by analyzing five disk-dominated RXTE spectra one reflection-dominated Suzaku spectrum. combination of constraints from has potential to provide more stringent tests metric. Our constraint on Johannsen deformation parameter $\alpha_{13}$ is $-0.15 < \alpha_{13} 0.14$...
The spatial distribution of population is closely related to land use and cover (LULC) patterns on both regional global scales. Population can be redistributed onto geo-referenced square grids according this relation. In the past decades, various approaches monitoring LULC using remote sensing Geographic Information Systems (GIS) have been developed, which makes it possible for efficient updating data. A Spatial Updating System (SPUS) developed gridded database China based sensing, GIS...
The iron line and the continuum-fitting methods are currently two leading techniques for measuring black hole spins with electromagnetic radiation. They can be naturally extended probing spacetime geometry around holes testing general relativity in strong field regime. In past couple of years, there has been significant work to use method test nature holes. this Letter, we show its capability constraining by analyzing 17 RXTE data X-ray binary LMC X-1.
Very steep reflection emissivity profiles in the inner part of accretion disks are commonly found analysis x-ray observations black hole binaries and active galactic nuclei, but there is some debate about their exact origin. While can be naturally produced by compact coronae close to holes, measured radial parameter further increased disk ionization profile when theoretical model assumes a with constant ionization. In this paper, we implement possibility relxill_nk, which package designed...
Insight-HXMT is the first Chinese X-ray astronomical mission. With a 1-250 keV bandpass, an energy resolution of 150 eV at 6 keV, and without being subject to pile-up distortions, it suitable study bright sources like Galactic black holes. In present paper, we observations binaries MAXI J1535-571 4U 1630-472 during their outbursts in 2017 2020, respectively. From analysis reflection features, are able infer hole spin parameter two sources. For J1535-571, find very close 1, $a_* = 0.9916 \pm...