A5071685839- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Procedures and Complications
- Renal and Vascular Pathologies
- Aortic Disease and Treatment Approaches
- Coronary Interventions and Diagnostics
- Ultrasound Imaging and Elastography
- Cardiovascular Health and Disease Prevention
- Advanced X-ray and CT Imaging
- Diagnosis and Treatment of Venous Diseases
- Optical Imaging and Spectroscopy Techniques
- Cardiac, Anesthesia and Surgical Outcomes
University of Leicester
1996-2025
Glenfield Hospital
2024
British Heart Foundation
2024
NIHR Leicester Biomedical Research Centre
2024
Leicester Royal Infirmary
1996-2013
University Hospitals of Leicester NHS Trust
2003
Abstract Introduction Transcranial Doppler ultrasonography (TCD) and Near-Infrared spectroscopy (NIRS) are indirect measures of neurovascular coupling (NVC). NVC is the relationship between cerebral blood flow neuronal activity to meet metabolic demands brain. No studies have integrated TCD-NIRS investigate feasibility measuring in those with dementia, delirium, depression. Methods 32 participants (median [IQR] age 73.0 [70.0,78.5], 50% female, healthy (HC, n = 10), depression (n 11),...
Studies suggest the physical and mechanical properties of vessel walls plaque may be clinical value in diagnosis treatment cardiovascular atherosclerotic disease. The purpose this pilot study was to investigate potential application ultrasound Tissue Doppler Imaging (TDI) Arterial Wall Motion (AWM) quantify simple wall motion indices normal diseased carotid arteries. 224 arteries (0–100% stenoses) were imaged 126 patients (age 25–88 years, mean 68 ± 11). Longitudinal sections bifurcation...
Introduction Following recommendations from the National Abdominal Aortic Aneurysm Screening Programme (NAAASP), an audit was performed to assess impact of measuring inner rather than outer aortic wall diameters during scans for abdominal aneurysm. Methods Inner and were taken a prospective series 302 patients attending Vascular Studies Unit at Leicester Royal Infirmary routine ultrasound screening or surveillance their aorta. Absolute differences, as well potential on patient management,...
Cerebral blood flow (CBF) describes the volume of flowing through vessels that supply brain. The ability to regulate CBF can have profound effects on important cognitive processes and loss such regulation lead serious consequences brain homeostasis due susceptibility harmful systemic pressure changes. Partial carbon dioxide (PaCO2) is a key mediator CBF, causing decreased in low PaCO2 increased high PaCO2, facilitated changes vasculature known as cerebrovascular reactivity (CVR). CVR able by...