BaTiO3 (BTO) ceramics were fabricated based on stereolithography technology. The microstructures and electric properties of the BTO studied. X-ray patterns sintered indicated that tetragonal phase had formed, grain size increased clearly as weight percentage increased. Moreover, exhibited good properties, with a piezoelectric constant d33 166 pC/N at 80% percentage. To evaluate 3D printed ceramics, 1.4 MHz focused ultrasonic array was characterized. -6dB bandwidth 40%, insertion loss center...

Optical-resolution photoacoustic microscopy (OR-PAM) has been significantly improved in terms of spatial resolution, detection sensitivity, imaging speed, and penetration depth. However, the popular producibility OR-PAM system is still limited by size cost solid-state laser excitation. Here, we developed a portable laser-diode-based (LD-OR-PAM) using pulsed semiconductor source, which was operated at 905 ± 15 nm with pulse energy as low 4.9 μJ. The measured lateral resolution to ∼1.5 μm from...

We have developed an intravascular confocal photoacoustic (PA) endoscope with symmetrically aligned dual-element ultrasonic transducers. By combining focused laser excitation and acoustic collection, the PA is capable of realizing resolution enhanced imaging improved signal-to-noise ratio (SNR) to ameliorate reduction caused by scattering increasing tissue depth. The detection sensitivity 5 dB compared that single transducer endoscope, transverse system can up 13 μm. Intravascular tomography...

Abstract The backing layer is the core component of an ultrasonic transducer, which can absorb acoustic energy and suppresses excess vibration to obtain a broad bandwidth pulse-echo signal. Ultrasound-assisted 3D printing control orientation/alignment local composition particles in liquid resin fabricate materials with periodic complex structures. In this paper, three types tungsten/photosensitive composites (1-3, 2-2, 3-3) were prepared using ultrasound-assisted stereolithography technique....

We present a 3D-visual laser-diode-based photoacoustic imaging (LD-PAI) system with pulsed semiconductor laser source, which has the properties of being inexpensive, portable, and durable. The source was operated at wavelength 905 nm repetition rate 0.8 KHz. energy density on sample surface is about 2.35 mJ/cm(2) pulse as low 5.6 μJ. By raster-scanning, preliminary 3D volumetric renderings knotted helical blood vessel phantoms have been visualized integrally an axial resolution 1.1 mm...

Objective.Ultrasound neuromodulation has become an emerging method for the therapy of neurodegenerative and psychiatric diseases. The phased array ultrasonic transducer enables multi-target ultrasound in small animals, but relatively large size mass thick cables limit free movement animals. Furthermore, spatial interference may occur during brain stimulation with multiple micro transducers.Approach.In this study, we developed a miniature power used virtual source time inversion 3D printing...

The piezoelectric materials, such as ceramics, crystals, and films, have wide applications in the mechanical industry, medical imaging, electronic information, ultrasonic devices, etc. Generally, adding oxide dopants, or introducing new solid solutions to form morphotropic phase boundary of materials were common strategies enhance electric properties. In recent decades, rare-earth elements doped attracted much attention due their multifunctional performances combining photoluminescence...

Transcranial focused ultrasound (tFUS) is increasingly used in experimental neuroscience due to its neuromodulatory effectiveness animal studies. However, achieving multitarget tFUS small animals typically limited by transducer size, energy transfer efficiency, and brain volume. The objective of this work was construct an system for neuromodulation animals. First, a miniaturized high-powered 2-D array developed. phase delay each element calculated based on the multifocal time-reversal...

Transcranial ultrasound therapy has become a noninvasive method for treating neurological and psychiatric disorders, studies have further demonstrated that multitarget transcranial is better solution. At present, in small animals can only be achieved by the multitransducer or phased array. However, multiple transducers may cause spatial interference, array system complicated, expensive, especially unsuitable animals. This study first to design fabricate miniature acoustic holography lens...

We developed a simple and compact laser-scanning photoacoustic microscopy (PAM) for imaging large areas of subcutaneous microvasculature in vivo. The reflection-mode PAM not only retains the advantage high scanning speed optical scanning, but also offers an field-of-view (FOV) up to 20 × mm 2 , which is largest FOV available models so far. lateral resolution system was measured be 17.5 µm. Image experiments on vivo mouse ears abdomen demonstrate system's potential fast high-resolution...

Objective.Exhaustion of Serotonin (5-hydroxytryptamine, 5-HT) is a typical cause the depression disorder's development and progression, including depression-like behaviors. Transcranial ultrasound stimulation (TUS) an emerging non-invasive neuromodulation technique treating various neurodegenerative diseases. This study aims to investigate whether TUS ameliorates behaviors by restoring 5-HT levels.Methods.The model mice are established chronic restraint stress (CRS). Ultrasound waves (FF =...

Objective.Monoamine dysfunction has been implicated as a pathophysiological basis of several mental disorders, including anxiety and depression. Transcranial ultrasound stimulation (TUS) is noninvasive nerve technic showing great potential in treating depression/anxiety disorders. This study aims to investigate whether TUS can ameliorate depression with mice by regulating brain monoamine levels.Approach.Mice received repeated subcutaneous injections corticosterone (CORT, 20 mg kg-1) for 3...

Metal/CFRP (carbon fiber reinforced plastic) hybrid composites are crucial in aerospace applications, demanding non-contact, high-resolution inspection. Traditional non-destructive testing methods face daunting technical challenges due to varying densities and impedance between metal layers. Here, a air-coupled laser-ultrasound (ACLU) system was presented for non-contact detection of internal microdefects on the non-homogeneous metal/CFRP interface. The near-surface resolution can reach as...

Solid-state laser systems, such as traditional Nd:YAG-based lasers, are commonly used for noninvasive biomedical photoacoustics with nanosecond pulse duration and millijoule energy. However, lasers both bulky expensive use a handy tool clinical applications. As an alternative, semiconductor light source has the advantages of being compact, inexpensive, robust. In addition, main drawback low peak output power may make it exactly suitable imaging modalities, which require relatively energies,...

In vivo identification of viable and thermally coagulated blood in a burn wound can be used to profile the type, extent, site burn, thus assisting removal necrotic tissue preparation for skin grafts. Recently, intensive research on photoacoustic imaging (PAI) has been conducted evaluate injury. However, most PAI systems usually take approach direct physical contact an acoustic detector or impedance matching medium with vulnerable burned skin, which exposes significant limitations diagnosis...