A5069488782- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Management of metastatic bone disease
- Sarcoma Diagnosis and Treatment
- Scoliosis diagnosis and treatment
- Reconstructive Surgery and Microvascular Techniques
- Shoulder Injury and Treatment
- Medical Imaging and Analysis
- Shoulder and Clavicle Injuries
- Surgical site infection prevention
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Cancer Diagnosis and Treatment
- Wound Healing and Treatments
- Orthopedic Infections and Treatments
- Bone Tumor Diagnosis and Treatments
- Hip and Femur Fractures
- Breast Implant and Reconstruction
- Foot and Ankle Surgery
- Bone fractures and treatments
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Nerve Injury and Rehabilitation
- Bone health and treatments
Albert Einstein College of Medicine
2022-2025
Hospital for Special Surgery
2021-2025
Montefiore Medical Center
2022-2025
Deutsche Forschungsgemeinschaft
2025
Cornell University
2025
Neurological Surgery
2025
Massachusetts General Hospital
2020-2024
Johnson & Johnson (Sweden)
2024
Duke University
2024
University of Pittsburgh
2016-2023
In situ cellular reprogramming offers the possibility of regenerating functional cardiomyocytes directly from scar fibroblasts, obviating challenges cell implantation. We hypothesized that pretreating with gene transfer angiogenic vascular endothelial growth factor (VEGF) would enhance efficacy this strategy.Gata4, Mef2c, and Tbx5 (GMT) administration via lentiviral transduction was demonstrated to transdifferentiate rat fibroblasts into (induced) in vitro by cardiomyocyte marker studies....
Robotics in spinal surgery offers a promising potential to refine and improve the minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) technique. Suitable surgeons for this technique include those who are already familiar with robotic-guided pedicle screw placement want advance their skillset by incorporating posterior-based fusion. We provide step-by-step guide MI-TLIF. The procedure is divided into 7 practical detailed techniques. steps sequential order include: (I) planning...
Background: The primary aim of this study was to evaluate the outcomes a series patients with Charcot neuroarthropathy (CN) who were evaluated in tertiary care setting. We hypothesized that those CN presented Charcot-related foot wound would have lower rates successful limb salvage than without wound. Methods: Two hundred forty-five (280 feet) identified diabetic during time period from January 1, 2005, June 2015. This consecutive cohort treated by single surgeon and had mean age 57.9 ± 10.0...
Abstract Purpose The objective of this study was to evaluate the reporting racial, ethnic, and socioeconomic data in clinical trials exploring management metastatic spine disease (MSD). Methods We undertook a cross-sectional analysis North American completed published registered on ClinicalTrials.gov patients with MSD. Data patient demographics, trial characteristics, race ethnicity, distribution racial ethnic groups, measures extracted from related publications identified through PubMed...
Study Design. Retrospective cohort study Objective. To compare distal lordosis (DL) and lumbar (LL) generated by single-level minimally invasive transforaminal interbody fusion (MI-TLIF) open TLIF at L4-L5 L5-S1. Summary of Background Data. Restoring or maintaining L4-S1 DL LL is an important component surgery. However, the current literature conflicting regarding effect surgical approach on these postoperative sagittal parameters. Methods. Preoperative were compared to values among adult...
Although its FDA-approved applications are limited, the pro-osteogenic benefits of recombinant human BMP-2 (rhBMP-2) administration have been shown in off-label surgical applications. However, effects rhBMP-2 on ankle fusions insufficiently addressed literature, which fails to include a case-control study adequate sample size evaluate efficacy treatment.In this we asked whether treatment (1) would increase rate successful fusion complex patients (patients with comorbidities associated poor...
OBJECTIVE Frailty is recognized as an important consideration in patients with cancer who are undergoing therapies, including spine surgery. The definition of frailty the context spinal metastases unclear, and few have studied such markers their association postoperative outcomes survival. Using national databases, metastatic tumor index (MSTFI) was developed a tool to predict this specific patient population has not been tested external data. purpose study test performance MSTFI...
Cancer patients with spinal metastases may undergo surgery without clear assessments of prognosis, thereby impacting the optimal palliative strategy. Because morbidity adversely impact recovery and initiation adjuvant therapies, evaluation risk factors associated mortality complications is critical. Evaluation body composition cancer as a surrogate for frailty an emerging area study improving preoperative stratification.
The ability to predict survival accurately in patients with osseous metastatic disease of the extremities is vital for patient counseling and guiding surgical intervention. We, Skeletal Oncology Research Group (SORG), previously developed a machine-learning algorithm (MLA) based on data from 1999 2016 90-day 1-year surgically treated extremity bone metastasis. As treatment regimens oncology continue evolve, this SORG MLA-driven probability calculator requires temporal reassessment its...
Abstract Background This study sought to identify associations between the Yost Index, a geocoded area neighborhood socioeconomic status (nSES) score, and race/ethnicity with patient refusal of recommended surgery for metastatic bone disease. Methods Patients disease were extracted from Surveillance, Epidemiology, End Results database. The Index was using factor analysis categorized into quintiles census tract-level American Community Service (ACS) 5-year estimates seven nSES measures....