A5072434378- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Bone health and osteoporosis research
- Bone fractures and treatments
- Liver Disease Diagnosis and Treatment
- Hip and Femur Fractures
- Management of metastatic bone disease
- dental development and anomalies
- Organ Transplantation Techniques and Outcomes
- Osteoarthritis Treatment and Mechanisms
- Veterinary Orthopedics and Neurology
- Hip disorders and treatments
- Liver Disease and Transplantation
- Veterinary Equine Medical Research
- Sarcoma Diagnosis and Treatment
- Connective tissue disorders research
- Bone and Dental Protein Studies
- Abdominal vascular conditions and treatments
- Shoulder Injury and Treatment
- Bone health and treatments
- Bone and Joint Diseases
- Pelvic and Acetabular Injuries
- TGF-β signaling in diseases
- Research in Social Sciences
Coxa Hospital
2013-2022
Tampere University
2019-2021
Jorvi Hospital
2005
Päijät-Hämeen Keskussairaala
2000
University of Eastern Finland
1991-1999
Moisio Hospital
1998
Kuopio University Hospital
1995
Background and purpose High age is associated with increased postoperative mortality, but the factors that predict mortality in older hip knee replacement recipients are not known.Methods Preoperative clinical operative data on 1,998 primary total replacements performed for osteoarthritis patients aged ≥ 75 years a single institution were collected from joint database compoared data. Average follow-up was 4.2 (2.2–7.6) who survived. Factors analyzed using Cox regression analysis, adjustment...
Background Chronic eosinophilic rhinosinusitis underlies a range of respiratory disorders including nasal polyposis. Surgical and medical methods are used to control polyps, with topical steroids commonly being for their anti‐inflammatory properties. Fluticasone propionate drops (FPND) is formulation developed specifically an effective well tolerated corticosteroid treatment Objectives To assess efficacy tolerability FPND in the bilateral polyposis adults. Methods This multicentre,...
Study Design. Skeletal tissues of mice with an inactivated allele the Col2a1 gene for Type II collagen ("heterozygous knockout") were studied. Objective. To determine whether a heterozygous inactivation has role in etiology spine disorders such as disc degeneration. Summary Background Data. Mutations COL2A1, COL11A1, COL11A2, and COL9A2 genes have been linked to disorders. However, mechanism by which genetic factors lead degeneration still are largely unknown. Methods. Spine studied using...
In this randomized prospective study the short- and long-term outcomes of patients undergoing inguinal hernia repair with either Lichtenstein mesh or Prolene Hernia System (PHS) were evaluated.Postoperative pain time to return work, driving sporting hobbies recorded after 300 repairs done by one two methods. Long-term sequelae complications assessed at follow-up visits 1 week, month year operation.The median duration operation for unilateral primary was 37 min 27 PHS procedure (P < 0.001)....
Abstract The aim of this study was to evaluate the effects long-term running training on structural properties bone. Ten beagle dogs ran according a strenuous progressive program (up 40 km/day) for 1 year. At end program, there significant reduction in bone mineral density 9.7%) vertebrae runner as compared with 10 sedentary control dogs. Polarized light microscopy vertebral trabecular bone, however, displayed proportionally higher retardation values collagen network than dogs, suggesting...
Background and purpose - Low-energy acetabulum fractures are uncommon, mostly occur in elderly patients. Determining the optimal operative treatment for such is challenging. Here we investigated whether acutely performed total hip arthroplasty plus posterior column plating (THA) reduced complications reoperations compared with open reduction internal fixation (ORIF) patients acetabular fractures. Patients methods We retrospectively reviewed records of 59 patients, > 55 years age, complex...
Abstract Background The purpose of this study was to determine the mid-term clinical, radiographic and health-related quality life (HRQoL) outcomes define survival rate in patients who had undergone revision total knee arthroplasty (TKA) using single rotating hinged (RHK) design. Methods Between January 2004 December 2013, 125 TKAs were performed at our institution RHK implant. We conducted both a retrospective analysis prospectively collected outcome data these prospective follow-up all 39...
The US Food and Drug Administration the UK Medicines Health Regulation Agency recommend using MRI in evaluation of patients with large-diameter metal-on-metal (LD-MoM) hips. Such recommendations do not take into account relevance repeated cross-sectional imaging. We therefore investigated natural course pseudotumors LD-MoM hip replacements.
Background and purpose — The pelvis is the 3rd most common site of skeletal metastases. In some cases, periacetabular lesions require palliative surgical management. We investigated functional outcome, complications, implant patient survival after a modified Harrington's procedure.Patients methods This retrospective cohort study included 89 cases surgically treated All patients were with procedure including restoration ring. Lesions classified according to Harrington. Functional outcome was...
Background and purpose - There has been increasing alarm regarding metal-on-metal (MoM) joint replacements leading to elevated levels of metal ions adverse reactions debris (ARMDs). is little information available concerning the prevalence risk factors for these reactions, except with MoM hip replacements. We determined in blood rate revision due ARMDs patients treated hinge total knee arthroplasty (TKA). Patients methods 22 TKAs connecting mechanisms were studied whole-blood chromium cobalt...
Abstract The effects of long-term running exercise were studied in 20 beagle dogs. A total 10 dogs ran from the age 15 weeks to 70 a progressive program for up 40 km/day. sister spent study period individual cages. When old, bone mineral density vertebrae, hip, and radius was analyzed by dual-energy x-ray absorptiometry (DEXA; Lunar) vertebrae also assessed quantitative computed tomography (QCT; Siemens DR 1). Mineral lower than controls. difference greatest spine QCT analysis. Blood...
Background and purpose — There is limited amount of evidence about optimal revision indications, technique, implants when performing surgery for metal-on-metal (MoM) hip replacements due to adverse reaction metal debris (ARMD). We assessed which factors are related re-revisions complications after a MoM arthroplasty because ARMD. also aimed provide information on these revisions. Patients methods 420 total arthroplasties (THA) 108 resurfacings were implanted later revised at our institution....
Clear cell chondrosarcoma is a rare bone neoplasm with low-grade clinical course and the potential to metastasize skeleton lungs. The aim of this report present case that extremely rare, but in accordance literature where clear reportedly has tendency for late metastases. In our patient primary surgery was intralesional, since it mistakenly interpreted as benign tumour early 80s. local recurrence lung metastases occurred, however, 29 years after initial treatment. resected wide margins, no...
This case study describes a total tibia resection and reconstruction with custom-made endoprosthetic replacement (EPR) long-term, 8-year follow-up. The patient underwent adamantinoma in 2009. Reconstruction was performed EPR, where both the knee joint ankle were reconstructed. Two muscle flaps, latissimus dorsi free flap pedicled medial gastrocnemius flap, used for soft tissue reconstruction. returned to normal life as kindergarten teacher, without complications eight years. demonstrated...