A5018466524- Air Quality and Health Impacts
- Carcinogens and Genotoxicity Assessment
- Heavy Metal Exposure and Toxicity
- Toxic Organic Pollutants Impact
- Pesticide Exposure and Toxicity
- Indoor Air Quality and Microbial Exposure
- Nanoparticles: synthesis and applications
- Pharmacology and Obesity Treatment
- Climate Change and Health Impacts
- Heavy metals in environment
- Chemical Safety and Risk Management
- Biomarkers in Disease Mechanisms
- Occupational and environmental lung diseases
- Cardiovascular Conditions and Treatments
- Muscle metabolism and nutrition
- Effects and risks of endocrine disrupting chemicals
- Trace Elements in Health
- Erythrocyte Function and Pathophysiology
- Antioxidant Activity and Oxidative Stress
- Energy and Environment Impacts
- Phytochemistry Medicinal Plant Applications
- Chemical Analysis and Environmental Impact
- Arsenic contamination and mitigation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Gestational Diabetes Research and Management
Universidade Federal do Rio Grande do Sul
2014-2024
University of Cruz Alta
2015-2017
In-Q-Tel
2015
Objective . Cognitive impairment reduces quality of life and is related to vascular neurodegenerative disorders. However, there also a close relationship between these diseases oxidative stress. Thus, the purpose this study was assess whether inflammation damage are associated with low cognitive performance in elderly different housing conditions. Methods The groups consisted 32 institutionalized 25 noninstitutionalized Brazilian subjects. Oxidative damage, markers, function were evaluated....
Toluene is an organic solvent used in numerous processes and products, including industrial paints. neurotoxicity reproductive toxicity are well recognized; however, its genotoxicity still under discussion, toluene not classified as a carcinogenic solvent. Using the comet assay micronucleus test for detection of possible genotoxic effects toluene, we monitored painters from Rio Grande do Sul, Brazil. The putative involvement oxidative stress genetic damage influences age, smoking, alcohol...
Children’s exposure to metals can result in adverse effects such as cognitive function impairments. This study aimed evaluate some toxic and levels of essential trace elements blood, hair, drinking water children from a rural area Southern Brazil. Cognitive ability δ-aminolevulinate dehydratase (ALA-D) activity were evaluated. Oxidative stress was evaluated main mechanism metal toxicity, through the quantification malondialdehyde (MDA) levels. included 20 an urban area. Our findings...
Several studies have associated exposure to environmental pollutants, especially polycyclic aromatic hydrocarbons (PAHs), with the development of cardiovascular diseases. Considering that 1-hydroxypyrene (1-OHP) is major biomarker pyrenes, purpose this study was evaluate potential association between 1-OHP and oxidative stress/inflammatory biomarkers in patients who had suffered an acute myocardial infarction (AMI). After adopting exclusion criteria, 58 post-infarction 41 controls were...
Because we have previously demonstrated the relation between polyphenol-rich foods (PRF) consumption and ductus arteriosus constriction, in this work, pregnant sheep were submitted to oral PRF intake for 14 days understand how process occurs. Fetal Doppler echocardiography, oxidative inflammatory biomarkers total polyphenol excretion evaluated.The high induced constriction by 71.6% increase systolic (P = 0.001) 57.8% diastolic velocities 0.002), 18.9% decrease pulsatility index 0.033), along...
Neonicotinoids represent the most used class of insecticides worldwide, and their precursor, imidacloprid, is widely marketed. The aim this study was to evaluate effect imidacloprid on activity hepatic δ-aminolevulinate dehydratase (δ-ALA-D), protective potential antioxidants against presence chemical elements in constitution pesticide. We observed that δ-ALA-D significantly inhibited by at all concentrations tested a dose-dependent manner. IC50 value obtained restoration enzymatic activity....
Abstract Background Gasoline is a complex mixture of saturated and unsaturated hydrocarbons, in which aromatic compounds, such as BTX (benzene, toluene, xylene) feature the main constituents. Simultaneous exposure to these hydrocarbons causes significant impact on benzene toxicity. In order detect early alterations caused gasoline station attendants exposed immunological, inflammatory, oxidative stress biomarkers were evaluated. Methods A total 66 male subjects participated this study. The...