A5041351032- Asthma and respiratory diseases
- Osteoarthritis Treatment and Mechanisms
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- HIV/AIDS Research and Interventions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Foot and Ankle Surgery
- Musculoskeletal pain and rehabilitation
- Tendon Structure and Treatment
- Clinical practice guidelines implementation
- Rheumatoid Arthritis Research and Therapies
- Health Promotion and Cardiovascular Prevention
- Sports injuries and prevention
- Clinical Reasoning and Diagnostic Skills
- Total Knee Arthroplasty Outcomes
- Dermatology and Skin Diseases
- Pharmaceutical studies and practices
- Orthopedic Surgery and Rehabilitation
- Inflammatory mediators and NSAID effects
- Emergency and Acute Care Studies
- Primary Care and Health Outcomes
- Chronic Disease Management Strategies
- Child and Adolescent Health
- Knee injuries and reconstruction techniques
- Healthcare Systems and Technology
Erasmus University Rotterdam
2016-2025
Erasmus MC
2016-2025
Huisarts en Wetenschap
2010-2022
Building Engineering and Science Talent
2022
Vrije Universiteit Amsterdam
2002-2021
Maastricht University
2009-2021
Radboud University Medical Center
2021
University Medical Center Groningen
2021
University Medical Center Utrecht
2009-2021
Radboud University Nijmegen
2021
During the Coronavirus Disease 2019 (COVID-19) pandemic, number of consultations and diagnoses in primary care referrals to specialist declined substantially compared prepandemic levels. Beyond deferral elective non-COVID-19 by healthcare providers, it is unclear what extent avoidance community-dwelling individuals contributed this decline routine utilisation. Moreover, uncertain which specific symptoms were left unheeded patients determinants predispose general population. In...
Although dizziness in elderly patients is very common family practice, most prevalence studies on are community-based and include a study population that not representative of practice. The aim this was to investigate the incidence reported by describe their final diagnoses as recorded physician, compare clinical characteristics dizzy with those non-dizzy patients. Data were obtained from Second Dutch National Survey General Practice, prospective registration which took place over 12-month...
Background and Purpose Cardiovascular risk factors are associated with an increased of dementia. Treatment hypertension hypercholesterolemia is a decrease in incident Whether interventions aimed at cardiovascular late life also reduce dementia unknown. Here, we report the outline pragmatic study that will attempt to answer this question describe prevalence target population. Methods We designed large cluster-randomized trial 6-year follow-up 3700 elderly subjects (70 78 y) assess whether...
This study examined whether vascular alterations are associated with the presence and progression of osteoarthritis knee, hip different hand joints in a large prospective cohort study.In this population-based involving participants aged 55 years older (Rotterdam Study I), men (n=2372) women (n=3278) were analysed separately. x-Rays scored using Kellgren Lawrence score for at baseline, after 6.6 10 years. Measures atherosclerosis (carotid intima media thickness (IMT) carotid plaque) data on...
Identification of individuals at high risk dementia is essential for development prevention strategies, but reliable tools are lacking stratification in the population. The authors developed and validated a prediction model to calculate 10-year absolute developing an aging population.In large, prospective population-based cohort, data were collected on demographic, clinical, neuropsychological, genetic, neuroimaging parameters from 2,710 nondemented age 60 or older, examined between 1995...
<h3>Abstract</h3> <b>Objective</b> To find an efficient set of diagnostic indicators that are optimally informative in the diagnosis a bacterial origin acute infectious conjunctivitis. <b>Design</b> Cohort study involving consecutive patients. Results index tests and reference standard were collected independently from each other. <b>Setting</b> 25 Dutch health centres. <b>Participants</b> 184 adults presenting with red eye either (muco)purulent discharge or glued eyelid(s), not wearing...
<h3>Background</h3> Patients with end-stage chronic obstructive pulmonary disease (COPD) experience poor quality of life and considerable problems in daily life. However, as they often do not actively express a wish for help, get the help need. <h3>Aim</h3> To gain insight into why patients COPD tend to help. <h3>Design study</h3> Prospective qualitative study semi-structured interviews. <h3>Setting</h3> Outpatient clinics four hospitals one centre specialising asthma Netherlands....
There is abundant literature on how to select and statistically deal with predictors in prediction models. Less attention has been paid the choice of outcome. We assessed impact different asthma definitions prevalence estimates model's performances. searched PubMed extracted data used diagnose childhood (between 6 18 yrs) cohort studies. Next, using from an ongoing study (n = 186), we constructed compared four models which all predict at age yrs, a fixed set turn. defined area clinical...
<h3>Background</h3> The use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with serious adverse drug events (ADEs). <h3>Aim</h3> To determine the prevalence over-the-counter (OTC) NSAID in general population and patients a high risk developing NSAID-related ADE. <h3>Design setting</h3> Cross-sectional study four practices Netherlands. <h3>Method</h3> Two patient samples were selected: random sample adults (general sample); adult ADE case (high-risk sample). All included sent...
GPs have high consultation rates for symptoms related to knee osteoarthritis (OA). Many risk factors symptomatic OA progression remain unknown.To define distinct pain trajectories in individuals with early and determine the these trajectories.Data were obtained from multicentre prospective Cohort Hip Knee study Netherlands. Participants OA, according clinical criteria of American College Rheumatology, a completed 5-year follow-up included.Baseline demographic, anamnestic, physical...
To improve information for patients and to facilitate a vaccination coverage that is in line with the EU World Health Organization goals, we aimed quantify how patient characteristics impact on influenza uptake of elderly people.An online discrete choice experiment (DCE) was conducted among 1261 representatives Dutch general population aged 60 years or older. In DCE, used scenarios based five characteristics: effectiveness, risk severe side effects, mild protection duration, absorption time....
Objective: To estimate the age and sex-specific prevalence of HIV infection in population Addis Ababa, Ethiopia. Design: Two-stage cluster sampling aged 0–49 years using kebeles (urban dwelling associations) as clusters. Methods: The sera used for this study were collected an earlier (1994) on rate acquisition antibodies against measles, rubella, hepatitis B. After separate approvals obtained from institutional ethics committees, tested by enzyme-linked immunosorbent assay confirmed Western...
To determine whether teledermatologic consultations can reduce referrals to a dermatologist by general practitioners (GPs).Multicenter cluster randomized controlled trial.We recruited 85 GPs from 35 practices in 2 regions the Netherlands (Almere and Zeist); 5 dermatologists nonacademic hospitals were also included study. Interventions The intervention used consultation system confer with dermatologist, whereas those control group referred their patients according usual practice. All...
Over the last five years, Dutch provision of out-of-hours primary health care has shifted from practice-based services towards large-scale general practitioner (GP) cooperatives. Only few population-based studies have been performed to assess demand for GP and emergency care, including referral patterns Accident Emergency Department (AED) by GPs ambulance services. During two four-month periods (five-year interval), a prospective cross-sectional study was population 62,000 people. Data were...