A5009686763- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Free Radicals and Antioxidants
- Metal-Catalyzed Oxygenation Mechanisms
- Galectins and Cancer Biology
- Trypanosoma species research and implications
- Seaweed-derived Bioactive Compounds
- Crystal structures of chemical compounds
- Research on Leishmaniasis Studies
- Nonlinear Optical Materials Research
- Phytochemicals and Antioxidant Activities
Universidade Federal de Santa Catarina
2021-2023
Chagas disease is a neglected tropical caused by the protozoan pathogen Trypanosoma cruzi. The major public health problem affecting about 6 to 7 million people worldwide, mostly in Latin America. available therapy for this based on two drugs, nifurtimox and benznidazole, which exhibit severe side effects, including resistance, cytotoxicity, variable efficacy inefficiency chronic phase. Therefore, new drugs are urgently needed. Coordination compounds may be an interesting alternative...
Abstract Reactive oxygen species (ROS) are closely related to oxidative stress, aging, and the onset of human diseases. To mitigate ROS-induced damages, extensive research has focused on examining antioxidative attributes various synthetic/natural substances. Coordination compounds serving as synthetic antioxidants have emerged a promising approach attenuate ROS toxicity. Herein, we investigated antioxidant potential series Fe(III) (1), Mn(III)Mn(II) (2) Cu(II) (3) coordination synthesized...