A5059441471- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Cavitation Phenomena
- Nanoparticle-Based Drug Delivery
- Luminescence and Fluorescent Materials
- Advanced Battery Technologies Research
- Ultrasound Imaging and Elastography
- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Porphyrin and Phthalocyanine Chemistry
- Nanoplatforms for cancer theranostics
Shenzhen University Health Science Center
2021-2023
Shenzhen University
2020-2023
Low-intensity focused ultrasound (FUS) has been shown to temporarily increase the permeability of blood-brain barrier (BBB) in presence circulating microbubbles (MB), facilitating delivery therapeutic agents brain. It is important understand short-term or long-term effect FUS/MB on cerebrovascular health and dynamic diffusion process brain interstitium vivo. In this study, an treatment platform was established observe FUS/MB-mediated BBB opening utilizing two-photon fluorescence imaging with...
Rapid short-pulse (RaSP) ultrasound with microbubbles is a novel modality for blood-brain barrier (BBB) opening and intracranial drug delivery, which has less energy thus probably safer compared the widely used long-pulse sequence. While previous work developing RaSP focused on assessing efficiency safety profile of BBB in healthy mouse brain mainly through vitro fluorescence microscopy histological staining, real-time process RaSP-induced blood-tumor (BTB) tumor model yet to be...
Delivery of therapeutic agents to the brain is limited by blood-brain barrier (BBB), which prevents intravenously-administered drugs from reaching central nervous system (CNS). Increasing permeability BBB temporarily with focused ultrasound combined microbubbles (FUS/MB) has great potential in non-invasive treatment CNS disorders. Thus, it important understand short-term or long-term effect vivo FUS/MB on cerebrovascular health and pharmacokinetics drugs. However, there a spatial temporal...