A5051282825- Reproductive Biology and Fertility
- Ovarian function and disorders
- Renal and related cancers
- Reproductive Health and Technologies
- Animal Genetics and Reproduction
- Sperm and Testicular Function
- Epigenetics and DNA Methylation
Ministry of Agriculture and Rural Affairs
2022-2025
Sichuan Agricultural University
2022-2025
ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational medicine. In case prepubertal girls, clinical challenge is pronounced, as ovarian tissue cryopreservation‐though promising‐remains an experimental technique necessitating rigorous scientific validation to guarantee developmental potential preserved materials facilitate broader adoption. To address these knowledge gaps,...
Previous studies have shown that the vitrification of metaphase II (MII) oocytes significantly represses their developmental potential. Abnormally increased oxidative stress is probable factor; however, underlying mechanism remains unclear. The walnut-derived peptide TW-7 was initially isolated and purified from walnut protein hydrolysate. Accumulating evidences implied a powerful antioxidant, while its prospective application in oocyte cryopreservation has not been reported. Here, we found...