A5085223811- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Obsessive-Compulsive Spectrum Disorders
- Tryptophan and brain disorders
- Cancer-related molecular mechanisms research
- Trypanosoma species research and implications
- Hepatitis B Virus Studies
- Ion Channels and Receptors
- RNA modifications and cancer
- Inflammasome and immune disorders
- Urticaria and Related Conditions
- Nephrotoxicity and Medicinal Plants
- Genetic Neurodegenerative Diseases
- Signaling Pathways in Disease
First Affiliated Hospital of Henan University of Traditional Chinese Medicine
2024
First Affiliated Hospital of Henan University
2024
Nanjing University of Chinese Medicine
2020-2022
Objective. Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by abnormal movements, phonations, and tics, but an accurate TS diagnosis remains challenging indeed depends on its description of clinical symptoms. Our study was conducted to discover verify some metabolite biomarkers based nontargeted targeted metabolomics. Methods. We untargeted ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MS) for preliminary...
Long non-coding RNAs (lncRNAs) play crucial roles in immune regulation and, therefore, may be closely related to the tumor microenvironment (TME). However, there are few studies regarding relationship between lncRNAs and TME liver cancer.Firstly, we constructed a lncRNA signature based on top 10 immune-inversely obtained from ImmLnc database performed disease-free survival (DFS) overall (OS) analyses for patients included Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC)...
Henoch-Schönlein purpura (HSP) is the most common vasculitis in children. Renal involvement main long-term complication of HSP, and presently there no way to predict which children may have irreversible renal damage from outset. This study aimed explore prediction value laboratory indexes on with could help early identification intervention.Children HSP hospitalized at First Affiliated Hospital Henan University Chinese Medicine June 2019 December 2020 were included. The demographic findings,...
Abstract Background Tourette syndrome (TS) is a chronic neuropsychiatric disorder, characterized by abnormal movements and phonations, tics, but accurate TS diagnosis remains challenging indeed depends on its description of clinical symptoms. Our study was to identify some metabolites biomarkers based non-targeted targeted metabolomics. Methods We conducted untargeted ultra-high-performance liquid chromatography -quadrupole time-off light mass spectrometry (UHPLC-Q-TOF/MS) for preliminary...
Jing-an oral liquid (JA) is a Chinese herbal formula used in the treatment of Tourette syndrome (TS); however, its mechanism unclear.To investigate effects JA on amino acid neurotransmitters and microglia activation vivo vitro.Sixty male Sprague-Dawley rats were divided into control group 5 TS groups. was induced with intraperitoneal injection 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (1 mg/kg) BV2 cells lipopolysaccharide. Control model administered saline, whereas groups (5.18, 10.36,...