A5050428511- Anesthesia and Pain Management
- Nausea and vomiting management
- Pain Management and Opioid Use
- Pain Management and Treatment
- Transcranial Magnetic Stimulation Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- Anesthesia and Sedative Agents
- Intraoperative Neuromonitoring and Anesthetic Effects
- Anesthesia and Neurotoxicity Research
- Nerve Injury and Rehabilitation
- Childhood Cancer Survivors' Quality of Life
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical studies and practices
- Epilepsy research and treatment
- Cancer Treatment and Pharmacology
- Management of metastatic bone disease
- Economic and Financial Impacts of Cancer
- Bone health and treatments
- Uterine Myomas and Treatments
- Cancer Diagnosis and Treatment
Assiut University
2014-2024
Luxembourg Institute of Socio-Economic Research
2021
Children Cancer Hospital
2016-2021
Lincoln Medical Center
2012
Abstract Background Significant analgesic effects of repetitive transcranial magnetic stimulation ( rTMS ) have been found in several studies patients with chronic pain various origins, but never for malignancy. The objective this study was to assess the efficacy 10 sessions over primary motor cortex M 1) suffering from malignant neuropathic pain. Methods Thirty‐four were randomly allocated into one two groups receive real (20 Hz, s, trains 80% intensity) or sham daily consecutive days....
Hepatocellular carcinoma (HCC) is frequently associated with visceral pain. Transcranial direct current stimulation (tDCS) has been proven to reduce chronic pain; however, its effectiveness in malignant pain unknown. This study aimed investigate the effects of tDCS patients due HCC. a randomized, sham-controlled, double-blind, prospective study. Forty HCC were enrolled and randomly assigned into two groups: real sham group; was applied over primary motor area (M1) for 10 consecutive days (2...
•Shortages were the main reason for unavailability of essential medicines used to treat paediatric cancers in Europe.•Financial barriers applied mostly lower-income countries and newly approved expensive across all settings.•Lack child-friendly formulations caused concerns over alignment with prescribed protocol parental distress.•There marked differences between access pain control children undergoing invasive procedures.•Urgent action is needed ensure equal Europe. BackgroundEssential...
<h3>Background and Objectives</h3> Poorly controlled postoperative pain is strongly associated with the development of chronic pain. We aimed to investigate effect topical morphine (in 1 3 doses: 5, 10, or 15 mg) on acute neuropathic after modified radical mastectomy for cancer breast. <h3>Methods</h3> In this registered clinical trial (ClinicalTrials.gov identifier: NCT02462577), 90 patients were allocated receive 10 mL plain bupivacaine 0.5% plus either mg (designated by group names...
The objective was to compare analgesic effect of combined epidural morphine-midazolam with either drug alone on postoperative pain in patients undergoing major abdominal cancer surgery.Eighty-four were allocated prospective randomized double-blind study receive analgesia. Patients received 5 mg morphine (Mor) group, midazolam (Mid) + (MM) 0.25% bupivacaine added injected solution same volume all groups. All groups compared time first request, total consumption, number doses, Visual Analog...
In breast cancer, painful bone metastases are common. Local radiotherapy is the standard treatment of metastases. Pain control and overall response rateswere low in alone. The objectives this study were to compare safety efficacy external beam with concurrent capecitabine vs. alone pain cancer patients. Eighty-four patients from participated prospective study. We randomized into two groups: group A treated 30 Gy 10 fractions B 825 mg/m2 every 12 hrs. concurrently same dose. There was no...
Objective: To investigate effect of ketamine–bupivacaine in thoracic paravertebral block (TPVB) on acute and chronic pain after breast cancer surgery.Study Design: Prospective randomized controlled study.Setting: Cancer Institute.Methods: Ninety patients were assigned to receive TPVB with 20 ml bupivacaine 0.25% (Group I), combined ketamine 0.5 mg/kg II) or 1 III). Assessments included; analgesia time, post-operative morphine consumption, VAS scores, hemodynamics, sedation, adverse events...
Background and objectives. To assess the efficacy of 10 sessions (once daily for days) repetitive transcranial magnetic stimulation (rTMS) on primary motor cortex (M1) in patients suffering from malignant visceral pain. Materials methods. Thirty four were included study. They divided randomly into two groups (17 each, using closed envelopes): real rTMS (20 Hz, trains with intertrain interval 30 s total pulses 2,000, intensity 80% threshold) sham (coil elevated angled away head). Stimulation...
Background: Transcranial direct current stimulation (tDCS) across cortical brain areas appears to improve various forms of pain, yet evidence tDCS efficiency and ideal target is lacking. This study aimed compare the add-on analgesic efficacy concentric electrode transcranial (CE-tDCS) over primary motor cortex versus insular on management chronic postmastectomy pain. Method: Prospective randomized double-blind sham-controlled enrolled eighty patients with pain that were randomly assigned...
Chemotherapy-induced nausea and vomiting (CINV) is an adverse outcome associated with chemotherapy sometimes difficult to manage. This study aimed examine the impact of a single session transcranial direct current brain stimulation (tDCS; 2 mA) over motor cortex for 20 minutes before in patients receiving highly emetogenic chemotherapy.Prospective randomized double-blind sham-controlled study.Academic medical center.Sixty breast cancer who were scheduled treatment selected allocated randomly...
Abstract Background Inadequate acute postoperative pain management is linked to the effect on stress response and development of chronic pain. A unique regional anaesthetic method that becoming more important for erector spinea plane block (ESP). Since its initial description, physicians have questioned weather this novel easy can take place paravertebral (PVB). Our goal was evaluate, in contrast control group, effects ESP & PVB post-mastectomy Methods One hundred five female patients...
Abstract Background Although laparoscopic surgery provides earlier recovery, less morbidity and hospital stay, however, severe pain is still a problem after it. Duloxetine has been recently used in postoperative management. We tested perioperative duloxetine to evaluate its effect on patients undergoing colorectal cancer surgery. Methods Sixty were enrolled this study divided into two equal groups; group each patient received an oral capsule (60 mg) 1st dose at night before surgery, the 2nd...
Magnesium sulfate (MgSO4) may enhance the effects of local anesthetics when used as an adjuvant in peripheral nerve blocks. Our objective was to evaluate efficiency and safety utilizing MgSO4 alongside levobupivacaine bilateral ultrasound-guided transversus abdominis plane (US-TAP) block for postoperative pain pediatric cancer patients who underwent abdominal surgery.A randomized double-blinded controlled trial at South Egypt Cancer Institute, Assiut University, Assiut, Egypt, included that...
Objectives: To assess the analgesic efficacy and tolerability of co-administration pre-emptive single oral dose sustained release morphine sub- anesthetic ketamine infusion for modified radical mastectomy (MRM) with axillary evacuation. Methods: Sixty four adult female patients scheduled MRM were divided to two groups, group (n=32) received preoperative tablet, 30 mg placebo tablet. Both groups bolus, 0.5 mg/kg followed by continuous 0.1 mg/kg/h 24 h postoperatively. VAS pain score, time...
Background:Breast cancer is the most frequent tumor in women.The incidence of breast cancer, as well need surgical treatment has increased probably due to awareness and improved diagnostic tools resulting early diagnosis favorable outcome [1] .Conventionally general anesthesia frequently used technique, but it associated with inadequate pain control lack residual analgesia also other Abstract: Background: Breast surgery one common forms conducted hospitals; even relatively minor can be...