Swine dysentery and necrotic enteritis are a bane to animal husbandry worldwide. Some countries have already banned the use of antibiotics as growth promoters in production. Surfactin is potential alternative antibacterial agents. However, activity Bacillus species-derived surfactin on Brachyspira hyodysenteriae Clostridium perfringens still poorly understood. In current study, effects produced from subtilis licheniformis B. C. were evaluated. Results showed that multiple isoforms detected...

Soybean meal is the main vegetable protein source in animal feed. contains several anti-nutritional factors, which directly affect digestion and absorption of soy protein, thereby reducing growth performance value animals. Fermented soybean rich probiotics functional metabolites, facilitates digestion, utilization piglets. However, mixed solid-state fermentation (SSF) conditions remain to be optimized. In this study, we investigated optimal parameters for SSF by Lactobacillus species...

The human gut microbiota creates a complex microbial ecosystem, characterized by its high population density, wide diversity, and interactions. Any imbalance of the intestinal microbiome, whether qualitative or quantitative, may have serious consequences for health, including small bacterial overgrowth (SIBO). SIBO is defined as an increase in number bacteria (103–105 CFU/mL), alteration composition, both intestine. PubMed, Science Direct, Web Science, EMBASE, Medline databases were searched...

Gamma-aminobutyric acid (GABA) is becoming more well-acknowledged for its ability to improve the development performance of poultry, particularly by interacting with Insulin-like growth Factor 1 (IGF-1) pathway. This review emphasizes importance GABA in optimizing poultry production thoroughly examining biochemical characteristics, physiological roles, and molecular mechanisms action. a crucial inhibitory neurotransmitter that not only regulates neuronal excitability but also optimizes...

Red1, Hop1 and Mek1 are three yeast meiosis-specific chromosomal proteins that uphold the interhomolog (IH) bias of meiotic recombination. is also an effector protein kinase in a checkpoint responds to aberrant DNA and/or axis structure. The activation requires Red1-dependent Hop1-Thr(T)318 phosphorylation, which mediated by Mec1 Tel1, homologs mammalian damage sensor kinases ATR ATM. As ectopic expression Mek1-glutathione S-transferase (GST) was shown promote IH recombination absence...

ABSTRACT Soybean meal (SBM) contains several anti-nutritional factors, which limit the use of soy protein. Exogenous enzyme supplementation and microbial fermentation can reduce factors increase bioavailability nutrients in SBM. In this study, we investigated optimal parameters for solid-state (SSF) SBM by protease combination with probiotics evaluated its effect on growth performance immune response broilers. Protease Bacillus subtilis significantly increased degradation soybean protein...

Prophylactic use of antibiotics in-feed has been effective in decreasing the incidence diarrhea weaning piglets. However, overuse as prophylactic or therapeutic agents animal feed leads to evolution drug-resistant bacteria and antibiotic residues pigs. This study investigated effects Bacillus licheniformis-fermented products on fecal microbial community A total 120 crossbred piglets with an average initial body weight 9.87 ± 1.43 kg were randomly allotted four dietary treatments consisting...

This study was aimed at investigating the effects of a defined concentration Fusarium mycotoxins, deoxynivalenol (DON) and zearalenone (ZON) incorporated into feeds on growth performance, blood biochemistry, immune response pigs alleviating mycotoxin degrading enzyme (MDE) toxicity mycotoxins.A total 48 weaning randomly allotted to four treatments (two replicates per treatment) including control, Toxins (1 ppm DON 250 ppb ZON), Toxin+MDE DON, ZON 1.5 kg MDE ton feed), alone (1.5 feed) for 6...

In the present study, we examined growth parameters of Bacillus licheniformis in solid-state fermentation (SSF) and evaluated effects licheniformis-fermented products on Clostridium perfringens-challenged broilers. During four six days SSF, highest viable biomass was observed at 5% glucose, 10% soybean meal, 3% yeast, 50% initial moisture content. The SSF were heat- acid-resistant. Furthermore, fermented able to inhibit perfringens Staphylococcus aureus vitro. feeding experiments, a similar...

Necrotic enteritis caused by Clostridium perfringens has reemerged as a severe poultry disease worldwide since the ban on routine use of antibiotics in animal feed. Probiotics are considered alternatives to antibiotic growth promoters. Bacillus species most common microorganisms used probiotics feed industry. The current study investigated and surfactin levels licheniformis solid-state fermentation using different substrates evaluated effects B. licheniformis-fermented products performance...

This study investigated the effects of fermented products produced by Bacillus licheniformis (fermented products) on growth performance and cecal microbial community in broilers exposed to coccidial challenge. A total 108 one-day-old male broiler chicks (Ross 308) were randomly allotted one three treatments. Each treatment was distributed into six replicate cages with birds each. The treatments consisted a basal diet without (NC), plus challenge (PC), 1 g/kg (FP). results indicated that FP...

Antibiotics have been used to maintain the overall health of poultry by increasing production efficiency, promoting growth, and improving intestinal function for more than 50 years. However, they a number side effects, such as antibiotic resistance, gut dysbiosis, destruction beneficial bacteria, potential spread diseases humans. In order address aforementioned issues, lot effort is put into development alternatives. One them use probiotics that can be added feed in increase performance...

Keywords: gut microbiota; small intestinal bacteria overgrowth; SIBO; diet, dysbiosis; microbial ecology.

Immunomodulatory feed additives might offer alternatives to antimicrobial growth promoters in poultry production.This experiment was carried out test the effect of β-glucan supplementation on performance and immune response broilers.Total 160 day-old broilers were randomly assigned 4 treatment groups fed corn-soybean diets containing 0, 0.012, 0.025 or 0.05% supplement a 6 week feeding experiment.Growth performance, antibody titer against New Castle vaccine, lymphocyte blastogensis,...

This study was conducted to evaluate the relative bioavailability (RBV) of 25-hydroxycholecalciferol (25-OH-D3) cholecalciferol (vitamin D3) in 1- 21-d-old broiler chickens fed with calcium (Ca)- and phosphorus (P)-deficient diets. On day hatch, 450 female Ross 308 were assigned nine treatments, five replicates ten birds each. The basal diet contained 0.50% Ca 0.25% non-phytate (NPP) not supplemented vitamin D. Vitamin D3 at 0, 2.5, 5.0, 10.0, 20.0 μg/kg, 25-OH-D3 1.25, 10.0 μg/kg. RBV...

Deoxynivalenol (DON) is the most prevalent mycotoxin in swine feedstuffs. The intestinal epithelial cells represent first target for DON. Here, we studied effects of DON and adsorbent agents on mitogen-activated protein kinase (MAPK) signaling pathways inflammation-associated gene expression porcine (IPEC-J2). Results showed that phosphorylation MAPK (p38, ERK, JNK) was increased after treatment or lipopolysaccharide (LPS) IPEC-J2 cells. p38, JNK not further enhanced co-treatment with LPS....

Bacillus licheniformis-fermented products (BLFP) are probiotics with antibacterial, antiviral, and anti-inflammatory properties that can improve growth performance. This study aimed to compare the fecal microbiota of diarrheal cats chronic diarrhea (n = 8) healthy 4) from same household using next-generation sequencing, evaluate effectiveness oral administration BLFP in relieving clinical signs altering intestinal cats. Six out eight showed improvement after for 7 days, stool condition other...

Two experiments were conducted to evaluate the effects of chromium (Cr) on growth performance, bone trait, serum traits, and immune responses in broilers.The broilers fed corn-soybean meal basal diet supplemented with Cr at level 0 (control), 200, 400, or 800 ppb form picolinate (CrPic).The treated diets for 6 weeks Exp. 1, but supplement was removed last 3 2. 1 showed that dietary did not affect performance broiler, though improved feed efficiency (p<0.05) observed during weeks.Moreover,...

Bacillus licheniformis (B. licheniformis) is commonly used as probiotic and its secondary metabolites are attractive anti-microbial candidate. In the present study, we aimed to evaluate antiviral activity of crude extracts from B. against porcine epidemic diarrhea virus (PEDV), a highly contagious enveloped that has caused great economic loss in pigs. vivo, PEDV-infected piglets supplemented with air-dried solid state fermentative cultivate containing licheniformis-fermented products (BLFP)...