A5019422085- Physical Activity and Health
- Mobile Health and mHealth Applications
- Health and Medical Studies
- Behavioral Health and Interventions
- Health disparities and outcomes
- Urban Transport and Accessibility
- Health Policy Implementation Science
- Scientific Computing and Data Management
- Diabetes Management and Research
- Research Data Management Practices
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Management and Placebo Effect
- Musculoskeletal pain and rehabilitation
- Diabetes Management and Education
- Neurological Disease Mechanisms and Treatments
- Biomedical Text Mining and Ontologies
- Neuroscience and Neuropharmacology Research
- Obesity, Physical Activity, Diet
- Urban Green Space and Health
- Intensive Care Unit Cognitive Disorders
- Meta-analysis and systematic reviews
- Aluminum toxicity and tolerance in plants and animals
- Health and Well-being Studies
- Chronic Disease Management Strategies
- Human-Animal Interaction Studies
Leibniz Institute for Prevention Research and Epidemiology - BIPS
2018-2024
University of Bremen
2018-2022
Maastricht University
2009
RWTH Aachen University
2000-2001
Regular physical activity (PA) is of central importance for healthy ageing. However, in Germany, only 42% older adults currently reach the PA recommendations World Health Organization. The aim this study was to examine effects two web-based interventions on aged 65–75 years living Northwestern Germany compared a delayed intervention control group (CG). 589 were randomized one three groups. Participants 1 (IG1) received access ten weeks assisting them self-tracking behavior. IG2 IG1 and...
Fewer than half of older German adults engage in the recommended levels endurance training.
We examined the expression of IL-6 within ischemic penumbra at various time points after transient (3 h) middle cerebral occlusion (MCA-O) in rats. The animals were killed 1, 3, 7 or 14 days following operation. Coronal brain sections processed for immunohistochemistry with antibodies against GFAP, OX 42, and Nissl-staining. Glial activation started on day one ischemia persisted up to 14. Expression was not present sham-operated controls. One MCA-O there several IL-6-positive cells penumbra....
Background Web‐based, theory‐driven interventions effectively promote older adults’ physical activity. Social‐cognitive mechanisms of their effect on stage change need to be further researched. Methods Older adults were randomly allocated intervention group 1 (10‐week online activity program), 2 (same program plus tracker), or delayed control group; n = 351 analyzed (59.6% originally individuals). Stages for recommended endurance and strength training social‐cognitive predictors assessed...
Abstract Background It remains unclear how physical activity (PA) interventions need to be designed reach older adults and widely accepted in this target group. The aim of study was assess the acceptance a web-based PA program, including individual intervention components as well relevant contextual factors, specify requirements for future interventions. Methods Two hundred sixty-six participants completed questionnaire covering program (content, structure, context). Further, 25 episodic...
Abstract FAIRification of personal health data is utmost importance to improve research and political as well medical decision-making, which ultimately contributes a better the general population. Despite many advances in information technology, several obstacles such interoperability problems remain relevant on topic interest likely be missed out due time-consuming search access processes. A recent example COVID-19 pandemic, where understanding virus’ transmission dynamics preventive...
Regular physical activity (PA) is of central importance for healthy aging and has a well-known impact on helping older adults maintain their cognitive health. Thus, we aimed to compare the effectiveness two interventions primarily conducted at home (print-based or web-based vs. plus use an tracker) health parameters in adults. Data participants (n = 551, 60–80 years) were analyzed after being randomly allocated waitlist control group (CG), print-based intervention (IG) that also included...
Despite the known health benefits of physical activity (PA), less than half and one-third older adults in Germany reach PA recommendations for endurance training strength training, respectively, World Health Organization. The aim this study is to investigate implementation effectiveness over course 9 months two interventions (information technology [IT]-based vs print-based) promotion among initially inactive a randomized, crossover trial. This part large research consortium (2015-2021)...
Zusammenfassung Das 2015 verabschiedete Präventionsgesetz sieht eine Stärkung settingbasierter Präventionsansätze vor. Ziel der vorliegenden Arbeit ist die Vorstellung des Community Readiness-Modells als ein Instrument zur Bedarfsermittlung und Verbesserung gesundheitsförderlicher Strukturen im Setting Kommune am Beispiel Bewegungsförderung Alter Rahmen Forschungsprojekts Ready to Change. Readiness steht dabei für kommunale Handlungsbereitschaft. Die Modell-Umsetzung erfolgt...
Selective study dropout limits manifestation and detection of intervention effects is a major challenge in behavioral studies. Engaging health-risk behaviors might make individuals especially dropout-vulnerable. Thus, this theory-based study's aim was to identify health-related lifestyle profiles affecting web-based physical activity trial targeting older adults.
Aims: Pooling the effect sizes of randomized controlled trials (RCTs) from continuous outcomes, such as glycated hemoglobin level (HbA1c), is an important method in evidence syntheses. However, due to challenges related baseline imbalances and pre/post correlations, simple analysis change scores (SACS) final values (SAFV) meta-analyses result under- or overestimation estimates. This study was aimed compare pooled estimated by Analysis Covariance (ANCOVA), SACS, SAFV meta-analyses, using...
Research is still lacking regarding the question as to how programs promote healthy ageing should be organized in order increase acceptance and thus effectiveness. For older adults, ecological factors, such physical distance program sites, might predict participation retention. Thus, key aim of this analysis was examine these factors a activity intervention trial. Adults (N = 8299) aged 65 75 years were invited participate n 589 participants randomly assigned one two groups with 10 weeks...
Although anatomical and biochemical properties of the rat entopeduncular nucleus (EPN) closely resemble those substantia nigra pars reticulata (SNr), present study shows that, unlike in SNr, focal cerebral ischemia does not cause trans-synaptic degeneration EPN neurons, despite striatal infarction a similar delayed glial activation both nuclei. In this study, interleukin-6 (IL-6) expression was found within neurons 3 7 days after ischemia. Since it has been reported that neuroprotective seem...
Physical activity (PA) is associated with benefits, such as fewer depressive symptoms and loneliness. Web- print-based PA interventions can help older individuals accordingly.We aimed to test the following research questions: Do delivered in a web- or mode improve self-reported stage of change, social-cognitive determinants PA, loneliness, depression? Is subjective age mediator change moderator this effect?Overall, 831 adults aged ≥60 years were recruited either allocated web-based...
<sec> <title>BACKGROUND</title> Despite wide acceptance in medical research, implementation of the FAIR principles (Findability, Accessibility, Interoperability, Reusability) is lacking certain health domains and interoperability across data sources remains a challenge. While clinical trial registries collect metadata about studies, numerous epidemiological public studies examining chronic disease burden remain unregistered or missing detailed information relevant study documents. Making...
Abstract Aim This study aimed to evaluate factors affecting older adults’ participation in a blended physical activity (PA) intervention, which comprised tailored home-based exercises and supervised on-site group sessions with peers. Specifically, the objective was explore participants’ feedback for identifying specific requirements regarding intervention components materials. Subject methods In 9-month randomized trial cross-over design targeting adults aged 60 above, web- print-based...
Abstract: Objective: Using the biopsychosocial model, this study evaluated an intervention targeting physical activity and extent of social participation among older adults. A longitudinal with participants randomized to print-based or IT-based interventions was conducted ( N = 251, M age 68.42, SD 5.35). Effects were assessed mixed model analyses serial mediation analyses. Results: Time had a significant effect [ F(2,358) 11.7, p < .001], increase in participation. Poor self-reported...
Zusammenfassung Hintergrund Regelmäßige körperliche Aktivität ist von zentraler Bedeutung für gesundes Altern. Allerdings halten in Deutschland weniger als ein Viertel der ab 65-Jährigen die Aktivitätsempfehlungen Weltgesundheitsorganisation ein. Ziel Arbeit In zwei Studienphasen (PROMOTE I und II) wurden web- print-basierte Programme zur Förderung körperlicher älterer Erwachsener 60 Jahren entwickelt mittels randomisierter Interventionsstudien analysiert evaluiert. dieses Beitrags es,...