A5039053742- Peripheral Nerve Disorders
- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Biomedical Text Mining and Ontologies
- Sarcoma Diagnosis and Treatment
- Shoulder Injury and Treatment
- Cerebrospinal fluid and hydrocephalus
- Biosimilars and Bioanalytical Methods
- Bone Tumor Diagnosis and Treatments
- Spine and Intervertebral Disc Pathology
- Musculoskeletal synovial abnormalities and treatments
- Genetics, Bioinformatics, and Biomedical Research
- Foot and Ankle Surgery
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Cell Image Analysis Techniques
- Organ Donation and Transplantation
- Pharmacovigilance and Adverse Drug Reactions
- Statistical Methods in Clinical Trials
- Spinal Hematomas and Complications
- Cancer Immunotherapy and Biomarkers
- Neurofibromatosis and Schwannoma Cases
SRH Hochschule Heidelberg
2022-2024
University of Peloponnese
2020
Johns Hopkins University
2011-2015
National and Kapodistrian University of Athens
2009-2015
NHS Fife
2015
Victoria Hospital
2015
Johns Hopkins Hospital
2011-2013
European Molecular Biology Laboratory
2012
State Hospital
2011
Bridgeport Hospital
2011
Understanding complex systems often requires a bottom-up analysis towards biology approach. The need to investigate system, not only as individual components but whole, emerges. This can be done by examining the elementary constituents individually and then how these are connected. myriad of system their interactions best characterized networks they mainly represented graphs where thousands nodes connected with vertices. In this article we demonstrate approaches, models methods from graph...
Abstract Introduction The optic nerve sheath diameter (ONSD) may be increased in brain-injured patients, especially children, with intracranial hypertension. We investigated whether measurements of ONSD correlated simultaneous noninvasive and invasive the pressure (ICP) adults. Methods Seventy-six critical care patients (58 males; 47 ± 18 years old) were included study. Fifty suffered from brain injury, whereas 26 had no pathology served as control individuals. Initially, evaluated...
The quantities of data obtained by the new high-throughput technologies, such as microarrays or ChIP-Chip arrays, and large-scale OMICS-approaches, genomics, proteomics transcriptomics, are becoming vast. Sequencing technologies become cheaper easier to use and, thus, evolutionary studies towards origins life for all species their evolution becomes more challenging. Databases holding information about how related they hierarchically organized expand rapidly. Clustering analysis is difficult...
Abstract Background Complexity is a key problem when visualizing biological networks; as the number of entities increases, most graphical views become incomprehensible. Our goal to enable many thousands be visualized meaningfully and with high performance. Results We present new visualization tool, Arena3D, which introduces concept staggered layers in 3D space. Related data – such proteins, chemicals, or pathways can grouped onto separate arranged via layout algorithms, Fruchterman-Reingold,...
Purpose To determine the added value of quantitative diffusion-weighted and dynamic contrast material–enhanced imaging to conventional magnetic resonance (MR) for assessment response soft-tissue sarcomas neoadjuvant therapy. Materials Methods MR examinations in 23 patients with who had undergone therapy were reviewed by two readers during three sessions: (T1-weighted, fluid-sensitive, static postcontrast T1-weighted), imaging, contrast-enhanced imaging. For each session, recorded features...
The sciatic nerve may normally exhibit mild T2 hyperintensity in MR neurography (MRN) images, rendering assessment of neuropathy difficult. purpose this case-control study was to evaluate whether a quantitative and qualitative analysis the nerves regional skeletal muscles increases accuracy MRN detecting neuropathy.We retrospectively reviewed studies pelvis thighs 34 subjects (12 men 22 women; mean [± SD] age, 50 ± 15 years), which 17 had final diagnosis according electrodiagnostic or...
Abstract Background Keeping up-to-date with bioscience literature is becoming increasingly challenging. Several recent methods help meet this challenge by allowing search to be launched based on lists of abstracts that the user judges 'interesting'. Some go further provide a second input set 'uninteresting' abstracts; these two sets are then used and rank relevance. In work we present service 'Caipirini' ( http://caipirini.org ) also allows sets, but takes novel approach ranking one or more...
Malignant peripheral nerve sheath tumors (MPNSTs) are the leading cause of mortality in patients with neurofibromatosis type-1 (NF1)); however, they may also arise sporadically. Differences magnetic resonance imaging (MRI) features between MPNSTs arising NF1 subjects versus non-NF1 have not been studied before. The accuracy MRI distinguishing from benign (BPNSTs) has debated. objective this study was to determine potential differentiating (a) NF1-related and non-NF1-related (b) BPNSTs.We...
Abstract Purpose: To evaluate whether the addition of three‐dimensional diffusion‐weighted reversed fast imaging with steady state free precession (3D DW‐PSIF) sequence improves identification peripheral nerves in distal extremities. Materials and Methods: Twelve MR neurography (MRN) studies upper extremity 12 MRN lower were evaluated. From 24 subjects who enrolled, 10 had clinically suspected neuropathy, whereas 14 suffered from various orthopedic diseases no clinical signs neuropathy. In...
Abstract Case reports suggest an association between second‐generation antipsychotics (SGAs) and serotonin syndrome (SS). The US Food Drug Administration (FDA) Adverse Event Reporting System (FAERS) was analyzed to generate hypotheses about how SGAs may interact with pharmacological targets associated SS. FAERS integrated additional sources link information adverse events drugs targets. Using Proportional Ratios, we identified signals that were further investigated the literature evaluate...
The development of monoclonal antibodies has dramatically changed the outcome patients with non-Hodgkin's lymphoma (NHL), most common hematological malignancy. However, despite satisfying results antibody treatment, only few NHL are permanently cured single-agent therapies. In this context, radioimmunotherapy, administration radionuclides conjugated to antibodies, is aimed augment efficacy immunotherapy in order deliver targeted radiation tumors, particularly CD20+ B-cell lymphomas. Based on...