A5060389184- Pancreatic function and diabetes
- Diabetes Management and Research
- Diabetes and associated disorders
- Mesenchymal stem cell research
- Wound Healing and Treatments
- HIV Research and Treatment
- CRISPR and Genetic Engineering
- Salivary Gland Disorders and Functions
- Diabetic Foot Ulcer Assessment and Management
- Vaccine Coverage and Hesitancy
- Metabolism, Diabetes, and Cancer
- Virus-based gene therapy research
- Autophagy in Disease and Therapy
- Neonatal and fetal brain pathology
- Psoriasis: Treatment and Pathogenesis
- Film in Education and Therapy
- Cannabis and Cannabinoid Research
- Hepatitis B Virus Studies
- Pressure Ulcer Prevention and Management
- Diet, Metabolism, and Disease
- COVID-19 Clinical Research Studies
- Galectins and Cancer Biology
- Sleep and related disorders
- Resilience and Mental Health
- Antibiotic Use and Resistance
Serum Institute of India (India)
2022-2025
Pacific Research Institute
2020-2024
Vitalant
2020-2024
University of Arizona
2023-2024
Dr. D. Y. Patil Medical College, Hospital and Research Centre
2020-2023
University of Florida
2021-2022
University of California, San Francisco
2020
Blood Systems Research Institute
2017
Northwestern University
2010
Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disease with difficult management, affecting the quality of life. Stem cell therapy has been proven to have regenerative ability. Using existing stem and modifying it, current study aims evaluate effect umbilical cord-derived mesenchymal cells (UCMSC), condition media (CM), UCMSC CM preconditioned methotrexate, reservetrol, vitamin D for its ability manage T1DM in Swiss albino mice. Materials & Methods: Disease was established...
Abstract: An autoimmune disorder known as type 1 diabetes (T1D) causes the pancreas to stop pro-ducing insulin. response against beta cells this metabolic condition, which is more typically observed in children and young adults a shortage of insulin hypergly-cemia.T1D development influenced by variety variables, including physiological events, ge-netic, epigenetic, immunologic, lifestyle variables. Biomarkers like glucose, glycated substances, C-peptides, autoantibodies, genetic biomarkers...
Background: Type 1 diabetes mellitus (T1DM) is a condition marked by elevated blood sugar levels and primarily recognized the destruction of beta cells caused an autoimmune attack, which significant characteristic T1DM. Recent studies have demonstrated regenerative potential conditioned medium therapy. In light this, current research sought to assess impact Mesenchymal Stem Cell media (CM) CM with resveratrol (CM+ Resveratrol) on management T1DM in Swiss albino mice. By leveraging modifying...
The phenotype of the cells present in ductal region salivary glands has been well characterized. However, it is imperative to identify novel biomarkers that can different cell types other glandular components for development therapeutic strategies and diagnostics gland disorders malignancies. Our study aimed at characterization expression distribution various surface markers, especially with a focus on CD29 human fetal as adult glands.Paired midgestation parotid, sublingual, submandibular...
Mesenchymal stem/stromal cells (MSCs) play crucial roles in maintaining tissue homeostasis during physiological turnovers and injuries. Very little is known about the phenotype, distribution molecular nature of MSCs freshly isolated human salivary glands (SGs) as most reports have focused on analysis cultured MSCs. Our results demonstrate that cell adhesion molecule CD34 was widely expressed by major SGs, namely parotid (PAG), sublingual (SLG) submandibular (SMG) glands. Further, gene...
Diabetes occurs due to insulin deficiency or less insulin. To manage this condition, administration as well increased sensitivity is required, but exogeneous cannot replace the sensitive and gentle regulation of blood glucose levels same β cells healthy individuals. By considering ability regeneration differentiation stem cells, current study planned evaluate effect metformin preconditioned buccal fat pad (BFP) derived mesenchymal (MSCs) on streptozotocin (STZ) induced diabetes mellitus in...
Antibiotics, first-line treatment for microbes-induced illnesses, indiscriminate use of which has led to increased resistance problems. Pharmacy students who are directly involved in drug distribution system should have sound knowledge about antibiotics and their resistance. The primary objective this study was assess awareness on its pharma students. carried out November 2017. Questionnaire prepared, validated, filled by Knowledge attitude towards antibiotic studied. First year final B....
Gene therapy-based HIV cure strategies typically aim to excise the provirus directly, or target host dependency factors (HDFs) that support viral persistence. Cure approaches will likely require simultaneous co-targeting of multiple sites within genome prevent evolution resistance, and/or HDFs fully render cells refractory infection. Bulk cell-based methods do not enable inference co-editing individual cell genomes, and discriminate between monoallelic biallelic gene disruption. Here, we...
The encounter of disorders associated with antibodies to neuronal enzymes caused a paradigm shift in understanding the CNS autoimmunity.The autoimmune targeting 65kDa isoform glutamic acid decarboxylase (GAD65) not only comprehends type 1 diabetes mellitus (T1DM), but also rather rare neurological disorders, including stiff-person syndrome (SPS), cerebellar ataxia, limbic encephalitis, and epilepsy.The patients these usually present T1DM suggests presence GAD65 antibodies.This is suggestive...
Abstract Introduction Repetitive Transcranial Magnetic Stimulation (rTMS) is a procedure by which magnetic coil used to stimulate specific regions of the brain bring about alterations in function. Continuous theta-burst stimulation (cTBS) form rTMS that was suppress cortical excitability and lower within network connectivity Default Mode Network (DMN). Connectivity DMN associated with rumination mind-wandering. Prior research indicates pre-sleep anxiety increased sleep latency decreased...
: At a large public university, we aimed to evaluate an intervention designed increase serogroup B meningococcal (MenB) vaccine uptake and awareness.
ABSTRACT CRISPR/Cas9 gene editing has the potential to revolutionize clinical management of HIV-1 infection, and may eliminate need for antiretroviral therapy (ART). Current therapies attempt either excise provirus or target entry receptors prevent infection new cells. Using a viral dynamic model, we determined that combining these two interventions, in presence absence ART, significantly lowers efficacy thresholds required achieve an cure. To implement this dual-targeting approach,...