A5079294263- Allelopathy and phytotoxic interactions
- Pesticide and Herbicide Environmental Studies
- Synthesis and biological activity
- Bioactive Compounds and Antitumor Agents
- Synthesis and Biological Evaluation
- Weed Control and Herbicide Applications
Universidade Federal de Alfenas
2018-2020
Natural and synthetic coumarins have been described as prototypes of new drug candidates against Chagas' disease. During a typical screening with compounds, we observed the potential nitrobenzoylcoumarin (1) trypanocidal Trypanosoma cruzi epimastigotas. Then, decided to prepare evaluate set analogues from 1 check major structural requirements for activity. The variations were conducted in six different sites on original compound best derivative (3) presented activity (IC50 28 ± 3 μM) similar...
Coumarins are widely distributed substances in plant species that promote phytotoxic effects, allowing them to be exploited as herbicides less harmful the environment, since many invasive have demonstrated resistance commercially available products. The derived coumarins used this study had not been tested models and their effect on plants was unknown. objective of evaluate action these bioassays with Lactuca sativa L., order select most responsive substance whose toxicity best elucidated by...