Two inorganic–organic hybrid compounds with zero-dimensional crystal structures, tetramethylphosphonium tetrachloroferrate(III) (compound 1, [(CH3)4P][FeCl4]) and tetrabromoferrate(III) 2, [(CH3)4P][FeBr4]), are discovered as multifunctional materials exhibiting simultaneously switchable dielectric, magnetic, optical properties. Despite the analogue chemical formulas, 1 2 crystallize in different noncentrosymmetric space groups, that is, P63mc F4̅3m, exhibit distinct responses three...

The aim of this study was to investigate the relationship between preoperative patient factors and postoperative half-year health care utilization reflecting recovery, common complications, comorbidities, significant concerns, identifying strong risk protective factors. This retrospective cohort utilized linear, quantile, ordinal regressions analyze Osaka National Health Insurance data from 26 606 elderly patients who underwent hip fracture surgery 2012 2018. key associated with multiple...

Abstract Background Exosome, a component of liquid biopsy, loaded protein, DNA, RNA and lipid gradually emerges as biomarker in tumors. However, exosomal circRNAs function mechanism gastric cancer (GC) are not well understood. Methods Differentially expressed GC healthy people were screened by database. The identification hsa_circ_000200 was verified RNase R sequencing, the expression evaluated using qRT-PCR. biological vitro. Western blot, RIP, fluorescence situ hybridization, double...

Obesity is an important cardiovascular risk factor. This study tested the effect of obesity reduction on preserving left ventricular ejection fraction (LVEF) and attenuating inflammation, oxidative stress LV remodeling in obese mice.Eight-week-old C57BL/6 J mice (n=24) were equally divided into control (fed a diet for 22 weeks), (high-fat diet, (OR) 14 weeks; then 8 weeks). Animals sacrificed at post 22-week high-fat myocardium collected. Heart weight, body abdominal-fat total cholesterol...

Anticoagulation therapy is indicated to prevent stroke in atrial flutter (AFL) and fibrillation (AF) patients. However, the outcomes of solitary AFL patients may differ from those with who develop AF during follow-up. This study aimed investigate differences clinical outcomes: (i) among AFL, AF, developing thereafter (ii) between vs. without anticoagulation therapy.

Five new biflorane-type diterpenoids, biofloranates E–I (1–5), and two bicyclic diterpene glycosides, lemnaboursides H–I (6–7), along with the known lemnabourside, were isolated from South China Sea soft coral Lemnalia bournei. Their chemical structures stereochemistry determined based on extensive spectroscopic methods, including time-dependent density functional theory (TDDFT) ECD calculations, as well a comparison of them reported values. The antibacterial activities compounds evaluated...

Atrial fibrillation (AF) is a leading cause of stroke, heart failure, and cardiovascular morbidity, yet its pathophysiology remains incompletely understood. Among various molecular regulators, microRNAs (miRNAs) have emerged as promising biomarkers for AF detection burden monitoring. However, the optimal sample type miRNA analysis unclear, posing challenge biomarker standardization. This study aimed to assess whether expression profiles remain consistent across plasma blood cells, with focus...

Recent interdisciplinary progress in flexible materials, devices, and system designs has brought about an emerging paradigm of skin‐like multifunctional electronic platforms named skin‐inspired electronics. Featured with excellent mechanical properties, thin conformal integrated sensing functions similar to those human skin, electronics exhibit great potential the application fields wearable human–machine interfaces. Many real‐world implementations intelligent healthcare monitoring,...

Cardiac and renal diseases are common disorders that frequently coexist. We tested the hypothesis levels of circulating endothelial-derived apoptotic microparticles (EDA-MPs; CD31(＋)CD42b(-)AN(-)V(＋)) platelet-derived (PDA-MPs; CD31(＋)CD42b(＋)AN(-)V(＋)) useful biomarkers for predicting presence cardiorenal disease (CRD).A total 68 patients with chronic kidney (CKD) angina pectoris (CKD-AP) undergoing cardiac catheterization were prospectively enrolled into group 1, 10 coronary artery (CAD)...

Atrial fibrillation (AF) is one of the risk factors for dementia. Female sex an inconsistent factor dementia after adjusting age in general population, and there lacks research on its impact developing patients with AF. This paper aims to investigate whether female a AF patients. Data newly diagnosed between 2001–2013 were retrieved from Taiwan’s National Health Insurance Research Database. Exclusion criteria were: incomplete demographic data, < 20 years, rheumatic heart disease,...

Electronic Skin: skin, the skin-like electronic system with sensory capabilities, is a rapidly developing research field. In article number 1900063, Li-jia Pan, Yi Shi, and co-workers give insights into new trend in incorporating skin intelligent modules achieving smart applications, paying close attention to interdisciplinary progress flexible materials, devices, designs terms of promising technical strategies potential real-world applications.

A prominent circadian variation is present in atrial fibrillation (AF) attacks that may be related to the expression of clock genes. Little known about genes AF. We prospectively enrolled 73 patients who had received pacemaker implantation, order define burden high-rate episodes (AHREs) accurately. AF was diagnosed clinically 43 (59%) (15 with persistent and 28 paroxysmal AF). The levels peripheral blood leukocytes were checked. There more males a larger left (LA) size lower BMAL1, CRY2,...

Obstructive sleep apnea syndrome (OSAS) is an important risk factor for atrial fibrillation (AF). GJA1 gene encoding connexin43, a major protein in cardiac gap junctions, plays crucial role the synchronized contraction of heart and arrhythmia. However, little known regarding expression incidence AF patients with OSAS. All prospectively enrolled OSAS underwent polysomnography, electrocardiography, 24-h Holter test, echocardiography. Moderate-to-severe was defined as apnea-hypopnea index (AHI)...

Obstructive sleep apnea syndrome (OSAS) is a significant risk factor for left atrial (LA) remodeling. Intermittent hypoxemia occurs during the cycle in patients with OSAS and plays crucial role cardiovascular pathologies such as stroke, arrhythmia, coronary artery disease. However, there very little information about of intermittent LA remodeling OSAS. In total, 154 sleep-related breathing disorders (SRBD) were prospectively recruited this study. All enrolled SRBD underwent polysomnography...

The implementation of competency-based medical education (CBME) focuses on learners' competency outcomes and performance during their training. Competencies should meet the local demands healthcare system achieve desired patient-centered outcomes. Continuous professional for all physicians also emphasizes training to provide high-quality patient care. In CBME assessment, trainees are evaluated applying knowledge skills unpredictable clinical situations. A priority program is essential in...

This review aimed to explore and map the literature on sleep quality assessments of adults in care settings using non-wearable trackers.

A previous study showed that high-glucose (HG) conditions induce mitochondria fragmentation through the calcium-mediated activation of extracellular signal-regulated kinase 1/2 (ERK 1/2) in H9C2 cells. This tested whether empagliflozin could prevent HG-induced this pathway. We found exposing cells to an HG concentration decreased cell viability and increased apoptosis caspase-3. Empagliflozin reverse effect stimulation on In addition, condition caused fragmentation, which was reduced by...

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly identified pathogen causing disease 2019 (COVID-19) pandemic. Hydroxychloroquine (HCQ), an antimalarial and anti-inflammatory drug, has been shown to inhibit SARS-CoV-2 infection in vitro tested clinical studies. However, lung concentration (6.7 µg/mL) predict the vivo antiviral efficacy might not be achievable with currently proposed oral dosing regimen. Further, high cumulative doses of HCQ may raise concerns...

Abstract Tetramethylphosphonium dichromate ([(CH 3 ) 4 P] 2 [Cr O 7 ], 1 undergoes a reversible phase transition at around 221 K. The results of the variable‐temperature single‐crystal X‐ray structural analyses and rotational potential energy calculations suggest that is probably related to order–disorder ] 2– anion. change space group from Pa ‐3 room temperature Pbca low reflected in peak‐like dielectric response. Tetraethylphosphonium trichromate ([Et 10 crystallizes monoclinic P / c...