A5080322299- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Mycobacterium research and diagnosis
- Urinary Tract Infections Management
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Food Safety and Hygiene
- Respiratory viral infections research
- Microbial infections and disease research
- Enterobacteriaceae and Cronobacter Research
- Parvovirus B19 Infection Studies
- Systemic Lupus Erythematosus Research
- Infection Control and Ventilation
- Microbial Metabolism and Applications
- Diagnosis and treatment of tuberculosis
- Data-Driven Disease Surveillance
- SARS-CoV-2 detection and testing
- Diphtheria, Corynebacterium, and Tetanus
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Education, Healthcare and Sociology Research
- Streptococcal Infections and Treatments
Akershus University Hospital
2015-2024
Introduction Targeted testing and treatment of latent TB infection (LTBI) are priorities on the global health agenda, but LTBI management remains challenging. We aimed to evaluate prognostic value QuantiFERON TB-Gold (QFT) test for incident TB, focusing interferon (IFN)-γ level, when applied in routine practice a low incidence setting. Methods In this large population-based prospective cohort, we linked QFT results Norway (1 January 2009–30 June 2014) with national registry data (Norwegian...
BackgroundKlebsiella pneumoniae species complex (KpSC) bloodstream infections (BSIs) are associated with considerable morbidity and mortality, particularly in elderly multimorbid patients. Multidrug resistant (MDR) strains have been poorer outcome. However, the clinical impact of KpSC phylogenetic lineages on BSI outcome is unclear.MethodsIn an 18-month nationwide Norwegian prospective study episodes adults, we used whole genome sequencing to describe molecular epidemiology KpSC,...
During the SARS-CoV-2 pandemic, healthcare workers (HCWs) are being exposed to infection both at work and in their communities. Determining where HCWs might have been infected is challenging based on epidemiological data alone. At Akershus University Hospital, Norway, several clusters of possible intra-hospital transmission were identified routine contact tracing.To determine whether suspected could be resolved by combining whole genome sequencing (WGS) with tracing data.Epidemiological...
The global prevalence of infections caused by extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) is increasing, and for Escherichia coli, observations indicate that this partly driven community-onset cases. ESBL-E population structure in the community scarcely described, data on risk factors carriage are conflicting. Here, we report fecal ESBL-producing E. coli Klebsiella pneumoniae (ESBL-Ec/Kp) a general adult population, examine factors, compare isolates with contemporary...
To compare the clinical and bacteriological outcomes of pivmecillinam treatment for community-acquired urinary tract infections (UTIs) caused by ESBL-producing Escherichia coli versus non-ESBL-producing E. in an outpatient setting. A prospective, multicentre, observational cohort study women aged ≥16 years, with pivmecillinam-treated UTIs or without ESBL production, recruited from primary care, was conducted period April 2013 to August 2016. Eighty-eight (mean age 49.4 years) were compared a...
To use the nationwide Norwegian surveillance programme on resistant microbes in humans (NORM) to address longitudinal changes population structure of Klebsiella pneumoniae isolates from 2001-15, focusing emergence and dissemination ESBL-producing K. Norway.Among blood (n = 6124) urinary tract 5496) we used Illumina technology whole genome sequence 201 130) urine 71), 667 non-ESBL blood. Complete genomes for four were resolved with Oxford Nanopore sequencing.In a highly diverse collection,...
We investigated 197 anaerobic isolates recovered from blood cultures in the period 2009-2013. The included were Bacteroides spp., Clostridium Prevotella Fusobacterium spp. and Gram-positive cocci (GPAC). Identification results by MALDI-TOF MS compared to those obtained 16S rRNA sequencing, MICs of benzylpenicillin, clindamycin, piperacillin-tazobactam, meropenem metronidazole determined Etests. correctly identified 94.9% anaerobes genus level, 86.8% species with errors mainly among...
Objective To compare mortality and length of hospital stay between patients with ESBL-producing E. coli bloodstream infections (BSIs) non-ESBL BSIs. We also aimed at describing risk factors for BSIs time to effective antibiotic treatment the two groups.
Introduction A year into the pandemic, knowledge of SARS-CoV-2 infection risks among healthcare workers remains limited. In this cross-sectional study, we examined whether with high exposure to Covid-19 patients had a higher risk than other in Norwegian University Hospital. We also investigated prevalence asymptomatic ward outbreak.
BAKGRUNN I norsk helsevesen gjennomføres omfattende tiltak for å hindre spredning av meticillinresistente Staphylococcus aureus (MRSA). Vi ønsket undersøke hvor mange smitteoppsporinger som gjøres rundt nyoppdagede MRSA-tilfeller hos pasienter og ansatte i sykehus, ofte smitteoppsporingene fører til ytterligere funn helsepersonell. MATERIALE OG METODE denne retrospektive observasjonsstudien bidro smittevernenhetene ved åtte helseforetak landets fire helseregioner med opplysninger om...
Background: Klebsiella pneumoniae bloodstream infections (BSIs) have considerable morbidity and mortality, particularly in elderly multimorbid patients. K. is a species complex (KpSC) composed of seven phylogroups. The clinical impact KpSC phylogenetic lineages on BSI outcome unclear, but multidrug resistant (MDR) strains been associated with poorer outcomes.Methods: In Norwegian nationwide, prospective study cases between 01.03.2017 30.08.2018, we used whole genome sequencing to describe...