A5088797027- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- Dental materials and restorations
- Nanoplatforms for cancer theranostics
- Bone and Dental Protein Studies
- Wound Healing and Treatments
- Bacteriophages and microbial interactions
- Oral microbiology and periodontitis research
- Scientific and Engineering Research Topics
- Connective tissue disorders research
- Dental Health and Care Utilization
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Antimicrobial Peptides and Activities
- Surgical Sutures and Adhesives
Sichuan University
2020-2024
State Key Laboratory of Oral Diseases
2022-2023
Chengdu University
2020
Bioadhesives are of great interest for tissue/wound closure to reduce surgical time, minimize treatment invasiveness, and prevent body fluid leakage.
Abstract Tooth enamel is prone to be attacked by injurious factors, leading a de/remineralization imbalance. To repair demineralized and prevent pulp inflammation caused biofilm accumulation, measures are needed promote remineralization inhibit bacterial adhesion on the tooth surface. An innovative material, poly (aspartic acid)-polyethylene glycol (PASP-PEG), was designed synthesized construct mineralizing anti-adhesive surface that could applied enamel. A cytotoxicity assay revealed low of...
Intracellular bacteria pose a great challenge to antimicrobial therapy due various physiological barriers at both cellular and bacterial levels, which impede drug penetration intracellular targeting, thereby fostering antibiotic resistance yielding suboptimal treatment outcomes. Herein, cascade-target bacterial-responsive delivery nanosystem, MM@SPE NPs, comprising macrophage membrane (MM) shell core of SPE NPs. NPs consist phenylboronic acid-grafted dendritic mesoporous silica nanoparticles...
We synthesized diblock copolymers with alendronate sodium self-absorbed, remineralizing capability and strong binding to fixed loose Ca 2+ ions. Combination treatment can suppress biofilm formation, alleviate enamels demineralization facilitate remineralization.
As an ideal biomaterial, the injectable dual crosslinking hydrogel can fill irregular shaped defects for treating bone defects. Despite advances in fabrication of hydrogels, current methods pose several limitations gelation process, such as unadjustable injectability, materials loss after injection and employment nonphysiological environments. A more rational designed should be shear-thinning self-healing quickly injection, which requires a reversible noncovalent or dynamic covalent...