- Pharmaceutical Practices and Patient Outcomes
- Asthma and respiratory diseases
- Electronic Health Records Systems
- Patient Safety and Medication Errors
- Pharmaceutical studies and practices
- Respiratory and Cough-Related Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ethics in Clinical Research
- COVID-19 Clinical Research Studies
- Rheumatoid Arthritis Research and Therapies
- Occupational and environmental lung diseases
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Technology and Patient Monitoring
- Biosimilars and Bioanalytical Methods
- Long-Term Effects of COVID-19
- Inhalation and Respiratory Drug Delivery
- Medication Adherence and Compliance
- Inflammatory Bowel Disease
- Ethics in medical practice
- Pharmaceutical Economics and Policy
- Health and Medical Research Impacts
- Cardiac electrophysiology and arrhythmias
- Occupational exposure and asthma
- Biomedical Ethics and Regulation
- Chronic Obstructive Pulmonary Disease (COPD) Research
Hospital La Paz Institute for Health Research
2018-2025
Universidad Autónoma de Madrid
2022-2024
Hospital Universitario La Paz
2015-2024
Hospital Central de la Defensa Gómez Ulla
2022
Centro de Investigación Biomédica en Red
2018
Major urban pollutants have a considerable influence on the natural history of lung disease. However, this effect is not well known in idiopathic pulmonary fibrosis (IPF).
Introduction Air pollution has a significant impact on the morbidity and mortality of various respiratory diseases. However, this not been widely studied in diffuse interstitial lung diseases, specifically idiopathic pulmonary fibrosis. Objective In study we aimed to assess relationship between four major air pollutants individually [carbon monoxide (CO), nitrogen dioxide (NO 2 ), ozone (O 3 oxides x )] development chronic failure, hospitalization due causes patients with Methods We...
Proton-pump-inhibitors are often prescribed unnecessarily in hospitals, which turn induces their prescriptions after discharge.To evaluate patients starting treatment with proton-pump-inhibitors during hospitalisation and proportion of inappropriate prescriptions. Patient risk factors whether initiation hospital induced continuation ambulatory care were also analyzed.An observational, cross-sectional study a tertiary (1350 beds) was carried out on the first Tuesday February 2015. Pharmacists...
To assess the safety of biological therapy for severe T2 asthma (omalizumab, mepolizumab, benralizumab and reslizumab) under real-life conditions in elderly patients older than 70 years.Retrospective data collection including clinical characteristics, comorbidities, treatment, disease control adverse events (AE) all with on years seen Severe Asthma Unit our hospital.Of 147 being treated biologics, 21 were included. The median age these was 76.3 (range 71-86) majority women (n = 18, 85.7%)....
Objective The aim of this retrospective multicentre study is to describe the clinical characteristics patients diagnosed with severe eosinophilic asthma receiving anti-IL-5/anti-IL-5Rα therapies and compare their effectiveness.
Anticoagulants are widely used in patients with pulmonary arterial hypertension (PAH) to prolong survival. However, there is a lack of robust evidence demonstrating the benefits anticoagulants PAH and very little known about complications their use this population. The objective study compare safety routine administration oral between who were not treated anticoagulants. This observational, retrospective cohort included consecutive confirmed from two centers: Brigham Women’s Hospital Boston...
The COVID-19 pandemic has posed a threat to hospital capacity due the high number of admissions, which led development various strategies release and create new beds. Due importance systemic corticosteroids in this disease, we assessed their efficacy reducing length stay (LOS) hospitals compared effect 3 different on outcome.We conducted real-world, controlled, retrospective cohort study that analysed data from database included 3934 hospitalised patients diagnosed with tertiary April May...
pressure of oxygen, mm Hg; Paw airway pressure, cm H2O/L/sec; PCT procalcitonine, ng/ml; Pplat plateau H2O; Raw resistance, TV tidal volume, ml/kg IBW (ideal body weight).ECMO was on day 4 and 14.Day 12, administration first dose reslizumab.Day 16, start empirical treatment with broad-spectrum antibiotherapy.No microorganisms were isolated at any time in microbiological samples (BAS, BAL, blood, urine.
<h3>Objectives</h3> To analyse the impact of computerised prescription order entry (CPOE) alerts on reduction errors due to medication interactions in prescribing process vitamin K antagonists. <h3>Methods</h3> Prospective study over 3 months a 1400-bed university tertiary care centre gifted with CPOE software, which includes interaction alerts. Adult patients receiving oral anticoagulant treatment antagonists international normalised ratio ≥4 were included. The reason for their...
The appearance of antitumor necrosis factor drugs (ATDs) has been a major advance in the management these patients. However, due to immunosuppressive effect therapies, side effects that require treatment discontinuations can appear. purpose this study was evaluate frequency ATD discontinuation adverse drug (ADEs) and influence different factors such as diagnosis, prescribed concomitant disease-modifying antirheumatic (DMARDs).Observational from prospective cohort conducted tertiary hospital...