Piotr Kaczmarek

ORCID: 0000-0001-6183-6539
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About
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Research Areas
  • Prenatal Screening and Diagnostics
  • Congenital Anomalies and Fetal Surgery
  • Congenital Diaphragmatic Hernia Studies
  • Pregnancy and preeclampsia studies
  • Congenital Heart Disease Studies
  • Fetal and Pediatric Neurological Disorders
  • Metal complexes synthesis and properties
  • Bladder and Urothelial Cancer Treatments
  • Theology and Canon Law Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Neonatal Respiratory Health Research
  • Urological Disorders and Treatments
  • Polish Historical and Cultural Studies
  • Shoulder Injury and Treatment
  • Pediatric Urology and Nephrology Studies
  • Renal and related cancers
  • Dermatological and Skeletal Disorders
  • DNA and Nucleic Acid Chemistry
  • Parvovirus B19 Infection Studies
  • Cardiovascular Issues in Pregnancy
  • Education and Cultural Studies
  • Birth, Development, and Health
  • Cardiac Valve Diseases and Treatments
  • Parathyroid Disorders and Treatments
  • Esophageal and GI Pathology

Lukasiewicz Research Network - Krakow Institute of Technology
2024

Polish Mother’s Memorial Hospital Research Institute
2008-2024

Christian Theological Academy in Warsaw
2024

Jan Kochanowski University
2024

Institute of Rural and Agricultural Development
2023

Rehasport Clinic
2013-2023

Łukasiewicz Research Network
2023

Papieski Wydział Teologiczny w Warszawie
2013-2020

Adam Mickiewicz University in Poznań
2017-2018

University of Fine Arts in Poznań
2018

The article presents analyses of long-term water quality data from the Warta River between 1958 and 2016. A clear increasing trend in nitrate concentrations was observed to early 1990s. This mainly related use fertilizers Poland this period. Then, after 1990s, a slow decreasing improvements sewage management more rational fertilizer political economic changes Poland. influence hydrological droughts on also investigated. Sharp increases concentration surface were accumulation contaminants...

10.1007/s11356-017-9798-3 article EN cc-by Environmental Science and Pollution Research 2017-08-12

Human α-defensin 5 (HD5, HD5ox to specify the oxidized and disulfide linked form) is a 32-residue cysteine-rich host-defense peptide, expressed released by small intestinal Paneth cells, that exhibits antibacterial activity against number of Gram-negative -positive bacterial strains. To ascertain contributions its array structure, antimicrobial activity, proteolytic stability, series HD5 double mutant peptides where pairs cysteine residues corresponding native linkages (Cys3-Cys31,...

10.1021/bi201043j article EN Biochemistry 2011-08-23

Interstitial cystitis/painful bladder syndrome is a chronic disorder with epithelial thinning or ulceration, pain, urinary frequency and urgency, for which there no reliably effective therapy. We previously reported that interstitial cells make glycopeptide antiproliferative factor ‘APF’ (Neu5Acα2‐3Galβ1‐3GalNAcα‐ O ‐TVPAAVVVA) induces abnormalities in normal similar to those vitro , including decreased proliferation, tight junction formation, increased paracellular permeability. screened...

10.1111/j.1747-0285.2011.01108.x article EN Chemical Biology & Drug Design 2011-02-26

Dystrophic cardiac calcinosis (DCC) occurs among certain inbred strains of mice and involves necrosis subsequent calcification as response myocardial tissue to injury. Using a complete linkage map approach, we investigated the genetics DCC in an F 2 intercross resistant C57BL/6J susceptible C3H/HeJ identified previously major predisposing quantitative trait locus (QTL), Dyscalc1, on proximal chromosome 7. Analysis inheritance suggested, however, that is influenced by additional modifier QTL,...

10.1152/physiolgenomics.2001.6.3.137 article EN Physiological Genomics 2001-08-28

Protonation and copper(II) coordination properties of kanamycin A were studied in solution by potentiometry, UV-Vis, circular dichroism (CD), EPR cyclic voltammetry (CV). Only mononuclear complexes stoichiometries ranging from CuH2L to CuH−2L found. Kanamycin anchors Cu(II) ions with an {NH2, O−} chelate the C-ring its molecule. At pH higher than 6 amino hydroxyl groups A-ring also participate binding. The resulting structure, similar that other unsubstituted aminoglycosides previously,...

10.1039/b203812a article EN New Journal of Chemistry 2002-01-01

Abstract River bank filtration (RBF) is a system that enriches groundwater resources by induced infiltration of river water to an aquifer. Problematic during operation RBF systems the deterioration effectiveness caused bed clogging. This situation was observed in Krajkowo well field which supplies fresh city Poznań (Poland) and after long hydrological drought between years 1989 1992. The present note discusses results specific hydrogeological research included drilling net boreholes depth 10...

10.1515/logos-2017-0021 article EN cc-by-nc-nd Geologos 2017-12-20

Literature reviews have described the applications of silver, copper, and zinc ions metallic particles Cu, Ti, Zn oxides, which been found to be useful antimicrobial reagents for biofunctionalization various materials their surfaces. For this purpose, compositions water dispersions containing emulsions synthetic copolymers based on acrylic vinyl monomers, polysaccharides (hydroxyethyl cellulose starch), additives with wetting stabilizing properties were used. Many stable different chemical...

10.3390/ma16165647 article EN Materials 2023-08-16

Pre-eclampsia is a systemic disease connected with high maternal and fetal morbidity mortality. Despite significant progress achieved in perinatal medicine, pre-eclampsia still one of the most current problems obstetrics.The aim study was to establish diagnostic algorithms for early late (PE) intrauterine growth restriction (IUGR).A total 320 pregnant women between 11 + 0 13 6 weeks gestation were recruited case-control study. The group consisted 22 patients PE, 29 PE 269 unaffected...

10.17219/acem/62214 article EN cc-by-nc-nd Advances in Clinical and Experimental Medicine 2017-06-30

The majority of aminoglycosidic antibiotics anchor Cu(ll) ions by {NH2, O} chelates the A and C rings its molecule as distinct from amikacin, which belongs to class substituted ones.The results indicate that all these effectively bind copper(ll) at physiological pH.Cyclic voltammetry investigations kinetic studies H202 disproportionation hydroxyl radicals detection made it possible support mechanism oxidative reactivity cupric complexes aminoglycosides, involves Cu(1) Cu(lll) redox states...

10.1155/s1565363304000056 article EN cc-by Bioinorganic Chemistry and Applications 2004-01-01

In mice, dystrophic cardiovascular calcification (DCC) is controlled by a major locus on proximal mouse chromosome 7 named Dyscalc1. Here we present strategy that combines in silico analysis, expression and extensive sequencing for ultrafine mapping of the Dyscalc1 locus. We subjected 15 laboratory strains to freeze-thaw injury heart, association with respective genotypes allowed condensation 1 Mb. Within this region, 51 known predicted genes were studied DCC-susceptible C3H/He DCC-resistant...

10.1152/physiolgenomics.00133.2006 article EN Physiological Genomics 2006-08-22

Background:Congenital malformations of the alimentary tract constitute 5% to 6% newborn anomalies, with congenital intestinal atresia being a common cause obstruction.This study explores advanced ultrasound diagnostic possibilities, including 2D, HDlive, HDlive inversion, and silhouette imaging modes, through analysis 3 cases involving duodenal obstructions.Congenital often present challenges in prenatal diagnosis.The most prevalent defect is leading obstruction, an incidence approximately 6...

10.12659/ajcr.943419 article EN cc-by-nc-nd American Journal of Case Reports 2024-02-23

Potentiometric measurements of ATP–His system proved an existence five adducts in the solution with stoichiometries ranging from H5(ATP)(His) to H(ATP)(His)4−. Their formation is a consequence electrostatic interactions only. In ternary Ni(II)–ATP–His system, two complex species NiH(ATP)(His)2− and Ni(ATP)(His)3−, were found. former, stacking interaction between aromatic moiety ATP imidazole ring L-histidine crucial adduct stability. All studied systems are able generate single strand...

10.1039/b508962j article EN Dalton Transactions 2005-01-01

We performed comprehensive structure−activity relationship (SAR) studies on the peptide portion of antiproliferative factor (APF), a sialylated frizzled-8 related glycopeptide that inhibits normal bladder epithelial and urothelial carcinoma cell proliferation. Glycopeptide derivatives were synthesized by solid-phase methods using standard Fmoc chemistry purified RP-HPLC; all intermediate final products verified HPLC-MS NMR analyses. Antiproliferative activity each derivative was determined...

10.1021/jm8002763 article EN Journal of Medicinal Chemistry 2008-09-13

This study obtained data on 22 fetuses in whom reversal of diastolic flow the middle cerebral artery (MCA) was seen. In 59% cases there normal heart function and 28% isolated tricuspid valve regurgitation. The majority (73%) presented with fetal anatomy most (82%) had a amniotic fluid index growth. all cases, Doppler results umbilical vein were normal. Of women, 65% no medication 73% did not smoke during pregnancy. MCA seen temporarily (for 2-30 min); however, one case rhesus factor disease...

10.1046/j.1469-0705.1997.09050324.x article EN Ultrasound in Obstetrics and Gynecology 1997-05-01

Maternal glycemic state is positively correlated with fetal insulin secretion. Randomized control studies have shown that treatment during pregnancy inhibits to some degree this effect. Our study aimed assess pancreas size in a population of treated mothers gestational diabetes.A cross-sectional, prospective observational was conducted. Pregnant women at 19-36 weeks gestation pre-gestational diabetes receiving therapy or either oral hypoglycemic were recruited. The circumference measured and...

10.5114/aoms/140578 article EN cc-by-nc-sa Archives of Medical Science 2021-08-04
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