Background . No strongly clinical evidence about the use of hand robot-assisted therapy in stroke patients was demonstrated. This preliminary observer study aimed at evaluating efficacy intensive function recovery, early phase after a onset. Methods Seven acute ischemic their first-ever were enrolled. Treatment performed using Amadeo robotic system (Tyromotion GmbH Graz, Austria). Each participant received, addition to inpatients standard rehabilitative treatment, 20 sessions treatment for 4...

Abstract The Ca2+-binding protein sorcin regulates intracellular calcium homeostasis and plays a role in the induction of drug resistance human cancers. Recently, an 18 kDa mitochondrial isoform was reported to participate antiapoptosis colorectal cancer (CRC), but information remains lacking about functional more abundant 22 expressed CRC. We found be widely CRC cells, whether or not they were resistant. Its upregulation drug-sensitive cells induced 5-fluorouracil, oxaliplatin, irinotecan,...

In the last few years, not many studies on use of robot-assisted therapy to recover hand function in acute stroke patients have been carried out. This randomized-controlled observer trial is aimed at evaluating effects intensive compared with occupational early recovery phases after a 3-month follow-up. Twenty their first-ever were enrolled and randomized into two groups. The experimental treatment was performed using Amadeo Robotic System. Control treatment, instead, out executed by trained...

Pyrolysis is carried out using beech wood for packed beds, consisting of pellets and particles various sizes, a block in the same shape size as beds. The different physical properties samples affect heat- mass-transfer rates and, consequently, conversion time. However, effects on yields composition lumped product classes are generally negligible. An exception observed beds made pulverized material, where re-evaporation pyrolysis vapors, previously migrated condensed cold zones, result...

This paper investigates the dynamics of lock-release gravity currents propagating upslope by laboratory experiments and shallow-water simulations. Both interface between dense ambient fluid instantaneous velocity field were measured image analysis. Different runs carried out varying initial density lock bed upslope. As a current moves upslope, layer becomes thinner, an accumulation region in part tank occurs. The speed decreases as increases, for highest up sloping angles, stops before...

SUMMARY In this paper the dynamics of a two‐layered liquid, made two immiscible shallow‐layers different density, has been investigated within framework lattice Boltzmann method (LBM). The LBM developed in for two‐layered, shallow‐water flow obtained considering separate sets equations, one each layer. coupling terms between have defined as external forces, acted on layer by other. Results from are compared with numerical results solving experimental and other published literature....

Unconfined three-dimensional gravity currents generated by lock exchange using a small dividing gate in sufficiently large tank are investigated means of eddy simulations under the Boussinesq approximation, with Grashof numbers varying over five orders magnitudes. The study shows that, after an initial transient, flow can be separated into axisymmetric expansion and globally translating motion. In particular, circular frontline spreads like constant-flow-rate, axially symmetric current about...

The dynamics of unconfined gravity currents generated by a lock-exchange with different lock widths is considered. were density differences caused salinity gradient and realized both numerically experimentally. Several runs carried out in order to study the role played width current dynamics. Numerical simulations performed new single-layer, 2D, shallow-water model, which accounts for dilution due entrained ambient fluid. By comparison between experimental numerical results, relevant...

Research interest on tsunami propagation and coastal impact in the Mediterranean Sea has recently grown due to recent catastrophic events, like ones Indian Pacific Oceans.A novel operational approach for evaluating tsunami-induced inundation, based a generalization of Green's law chain intermediate small-scale simulations, been proposed (Lalli et al. 2019; Melito al., 2022).The original Green’s provides amplitude long wave at given water depth, accounting only shoaling, while...

Comorbid anxiety disorders are frequently encountered in psychoses and mainly assessed during the hospitalization.Comorbidity was investigated 98 patients with schizophrenia, schizoaffective, or bipolar disorder, previously hospitalized for psychotic symptoms. Assessments, including Structured Clinical Interview Diagnostic Statistical Manual of Mental Disorders, Fourth Edition, Brief Psychiatric Rating Scale, Global Impressions were performed hospitalization (t0) subsequently a phase...

We provide numerical evidence of the transition from rank-ordered trains internal solitary waves (ISWs) to multi-humped packets. ascribe such peculiar and unexplored dynamics emergence a long-range influence among waves, mediated by hydrodynamic conditions developing in wake each ISW promoting acceleration trailing waves. Both train during its final configuration share features which are consistent with recently proposed theory ISWs propagating through moving stratified environments.

Abstract Patients with aortic arch pathologies after surgery for type-A acute dissection represent a challenging population since open is associated non-negligible rate of mortality and complications. Microinvasive endovascular repair Arch-Thoracic EndoVascular Aortic Repair (Ar-TEVAR) has shown promising results in high-risk patients. Ar-TEVAR usually performed under general anaesthesia. We report the case an 83-year-old man history ascending aorta replacement who was referred anastomotic...

Highlights•IFNs shape differentially the phenotype of sEVs release by MDM•IFNs-derived modulate T and B lymphocytes phenotype•IFN-γ/β-induced sEV IL-17 lymphocytesSummaryLimited information exists regarding impact interferons (IFNs) on carried extracellular vesicles (EVs). This study aimed at investigating whether IFN-α2b, IFN-β, IFN-γ, IFN-λ1/2 content EVs released primary monocyte-derived macrophages (MDM). Small-EVs (sEVs) were purified size exclusion chromatography from supernatants MDM...

In the field of sleep disorders, quality couple relationship is arousing increasing attention, given its implications for life and treatment adherence. The aim present study was to evaluate in a sample treated or untreated patients with Obstructive Sleep Apnoea Syndrome. Eighty-seven were recruited hospital-based Centre Medicine. Subjects administered Dyadic Adjustment Scale (DAS) quality, Epworth Sleepiness (ESS). Apnoea-hypopnoea indexes (AHI) collected through nocturnal polysomnography...

A new front condition for gravity currents in a two-layer shallow water framework with free surface is developed by applying the theory of weak formulation to first order system four partial differential equations written conservation form. The Rankine–Hugoniot jump conditions are applied and relation between velocity height shock obtained. Laboratory experiments on lock-release non-Boussinesq performed propagation displacement evaluated. Front velocities, predicted present mathematical...

Abstract Time resolved PIV encompassing moving and/or deformable objects interfering with the light source requires employment of dynamic masking (DM). A few DM techniques have been recently developed, mainly in microfluidics and multiphase flows fields. Most them require ad-hoc design experimental setup, may spoil accuracy resulting analysis. new technique is here presented which envisages, along a dedicated algorithm, fluorescent coating to allow for accurate tracking object. We show...

<i>Background:</i> Nevirapine (NVP) is a nonnucleoside reverse transcriptase inhibitor used in HIV patients and recently evaluated as differentiating antiproliferative agent human malignancies. However, while NVP safe treatment immunocompromised patients, NVP-containing regimens have been associated with severe immune-mediated toxicities non-HIV individuals. <i>Methods Results:</i> We describe the toxicity profile of single-agent 6 cancer treated for median period 7.3...