David J. Cox

ORCID: 0000-0001-6210-7311
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Research Areas
  • Indoor Air Quality and Microbial Exposure
  • Minerals Flotation and Separation Techniques
  • Air Quality and Health Impacts
  • Peptidase Inhibition and Analysis
  • Neuropeptides and Animal Physiology
  • Spectroscopy and Quantum Chemical Studies
  • Hemoglobin structure and function
  • Organometallic Complex Synthesis and Catalysis
  • Microfluidic and Capillary Electrophoresis Applications
  • Chemical and Physical Properties in Aqueous Solutions
  • Freezing and Crystallization Processes
  • Analytical Chemistry and Chromatography
  • Proteins in Food Systems
  • Crystallization and Solubility Studies
  • Protein purification and stability
  • Metabolism and Genetic Disorders
  • Protein Interaction Studies and Fluorescence Analysis
  • Mass Spectrometry Techniques and Applications
  • nanoparticles nucleation surface interactions
  • Behavioral and Psychological Studies
  • Field-Flow Fractionation Techniques
  • Electrostatics and Colloid Interactions
  • RNA and protein synthesis mechanisms
  • Particle physics theoretical and experimental studies
  • Insect Resistance and Genetics

Trinity College Dublin
2024

The Ocean Cleanup
2023

Endicott College
2022-2023

Behavioral Health Services
2022

QuanTech (United States)
2007-2021

Women's and Children's Hospital
2020

South Australia Pathology
2020

University of Florida
2018

Queensland Health
2017

BP (United Kingdom)
2010

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

10.1146/annurev.bi.35.070166.000421 article EN Annual Review of Biochemistry 1966-06-01

Objective: The objective of this study was to establish a national relative moldiness index for homes in the United States. Methods: As part Housing and Urban Development's American Healthy Homes Survey, dust samples were collected by vacuuming 2 m2 bedrooms plus living rooms from nationally representative 1096 States using Mitest sampler. Five milligrams sieved (300 μm pore, nylon mesh) analyzed mold-specific quantitative polymerase chain reaction 36 indicator species samples. Results: On...

10.1097/jom.0b013e3181255e98 article EN Journal of Occupational and Environmental Medicine 2007-08-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Amino Acid Composition of Bovine Pancreatic Carboxypeptidase A*Jean-Pierre Bargetzi, K. S. V. Sampath Kumar, David J. Cox, Kenneth A. Walsh, and Hans NeurathCite this: Biochemistry 1963, 2, 6, 1468–1474Publication Date (Print):November 1, 1963Publication History Published online1 May 2002Published inissue 1 November 1963https://pubs.acs.org/doi/10.1021/bi00906a046https://doi.org/10.1021/bi00906a046research-articleACS PublicationsRequest reuse...

10.1021/bi00906a046 article EN Biochemistry 1963-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBovine Pancreatic Procarboxypeptidase B. I. Isolation, Properties, and Activation*Erhard Wintersberger, David J. Cox, Hans NeurathCite this: Biochemistry 1962, 1, 6, 1069–1078Publication Date (Print):November 1962Publication History Published online1 May 2002Published inissue 1 November 1962https://pubs.acs.org/doi/10.1021/bi00912a017https://doi.org/10.1021/bi00912a017research-articleACS PublicationsRequest reuse permissionsArticle...

10.1021/bi00912a017 article EN Biochemistry 1962-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProcedures for the Isolation of Crystalline Bovine Pancreatic Carboxypeptidase A. II. Aα from Procarboxypeptidase A*David J. Cox, Freeman C. Bovard, Jean-Pierre Bargetzi, Kenneth Walsh, and Hans NeurathCite this: Biochemistry 1964, 3, 1, 44–47Publication Date (Print):January 1964Publication History Published online1 May 2002Published inissue 1 January...

10.1021/bi00889a008 article EN Biochemistry 1964-01-01

10.1016/0003-9861(69)90157-x article EN Archives of Biochemistry and Biophysics 1969-01-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProcarboxypeptidase A-S6.* Further Studies of its Isolation and PropertiesMakoto Yamasaki, James R. Brown, David J. Cox, Roderick N. Greenshields, Roger D. Wade, Hans NeurathCite this: Biochemistry 1963, 2, 4, 859–866Publication Date (Print):July 1, 1963Publication History Published online1 May 2002Published inissue 1 July 1963https://pubs.acs.org/doi/10.1021/bi00904a039https://doi.org/10.1021/bi00904a039research-articleACS PublicationsRequest...

10.1021/bi00904a039 article EN Biochemistry 1963-07-01

A procedure for purifying the insecticidal parasporal protoxin of Bacillus thuringiensis and a description its biochemical biophysical properties is provided. Mild alkali titration was necessary to generate functional in soluble form, anion-exchange chromatography used remove contaminating cytoplasmic proteases that are nonspecifically bound whole native crystals. Polyacrylamide gel electrophoresis, filtration chromatography, meniscus depletion sedimentation equilibrium analysis revealed an...

10.1016/s0021-9258(19)69714-0 article EN cc-by Journal of Biological Chemistry 1981-03-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBovine Pancreatic Procarboxypeptidase B. II. Mechanism of Activation*David J. Cox, Erhard Wintersberger, and Hans NeurathCite this: Biochemistry 1962, 1, 6, 1078–1082Publication Date (Print):November 1962Publication History Published online1 May 2002Published inissue 1 November 1962https://pubs.acs.org/doi/10.1021/bi00912a018https://doi.org/10.1021/bi00912a018research-articleACS PublicationsRequest reuse permissionsArticle...

10.1021/bi00912a018 article EN Biochemistry 1962-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preferential Hydration of Proteins in Concentrated Salt Solutions. I. Sedimentation Studies1David J. Cox and Verne N. SchumakerCite this: Am. Chem. Soc. 1961, 83, 11, 2433–2438Publication Date (Print):June 1, 1961Publication History Published online1 May 2002Published inissue 1 June 1961https://pubs.acs.org/doi/10.1021/ja01472a004https://doi.org/10.1021/ja01472a004research-articleACS PublicationsRequest reuse permissionsArticle...

10.1021/ja01472a004 article EN Journal of the American Chemical Society 1961-06-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preferential Hydration of Proteins in Concentrated Salt Solutions. II. Sedimentation Equilibrium Density Gradients1David J. Cox and Verne N. SchumakerCite this: Am. Chem. Soc. 1961, 83, 11, 2439–2445Publication Date (Print):June 1, 1961Publication History Published online1 May 2002Published inissue 1 June 1961https://pubs.acs.org/doi/10.1021/ja01472a005https://doi.org/10.1021/ja01472a005research-articleACS PublicationsRequest reuse...

10.1021/ja01472a005 article EN Journal of the American Chemical Society 1961-06-01

Trypsin inhibitor was isolated from seeds of opaque-2 corn by affinity chromatography on a trypsin/Sepharose column. The two major forms eluted the column were separated DEAE-cellulose in presence urea. One form is single-chain protein that has molecular weight approximately 12,500; second polypeptide chains and appears to have been produced exposure trypsin step. relationship an previously unspecified strain maize Hochstrasser et al. (Hochstrasser, K., Muss, M., Werle, E. (1967) Z. Physiol....

10.1016/s0021-9258(17)40944-6 article EN cc-by Journal of Biological Chemistry 1977-11-01

10.1016/s0003-9861(71)80055-3 article EN Archives of Biochemistry and Biophysics 1971-09-01

10.1016/0003-9861(67)90450-x article EN Archives of Biochemistry and Biophysics 1967-01-01

Abstract The transport of self-associating macromolecules on molecular sieve columns has been investigated by computer simulation. chromatographic behavior monomer-trimer, monomer-tetramer, and monomer-octamer systems simulated in order to study the effects several important variables reaction boundary shape. These include flow rate, gel porosity, particle diameter, development time, equilibrium constant. A given solute can be expected yield appreciably different profiles gels porosities...

10.1016/s0021-9258(18)62077-0 article EN cc-by Journal of Biological Chemistry 1971-07-01

Objective. Mold in water-damaged homes has been linked to asthma. Our objective was test a new metric quantify mold exposures asthmatic children’s three widely dispersed cities the United States. Methods. The Environmental Relative Moldiness Index (ERMI) created by US Protection Agency, with assistance Department of Housing and Urban Development (HUD), contamination homes. ERMI values children were determined for Boston, Kansas City, San Diego. Results. Asthmatic Boston (n = 76), City 60),...

10.3109/02770903.2012.740122 article EN Journal of Asthma 2012-11-09

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSedmientation equilibrium of protein solutions in concentrated guanidinium chloride. Thermodynamic nonideality and heterogeneityPetr Munk David J. CoxCite this: Biochemistry 1972, 11, 5, 687–697Publication Date (Print):February 29, 1972Publication History Published online1 May 2002Published inissue 29 February 1972https://pubs.acs.org/doi/10.1021/bi00755a004https://doi.org/10.1021/bi00755a004research-articleACS PublicationsRequest reuse...

10.1021/bi00755a004 article EN Biochemistry 1972-02-29

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThreonine-sensitive aspartokinase-homoserine dehydrogenase complex amino acid compositions, molecular weight, and subunit composition of the complexWillis L. Starnes, Petr Munk, Stephen B. Maul, Glenn N. Cunningham, David J. Cox, William ShiveCite this: Biochemistry 1972, 11, 5, 677–687Publication Date (Print):February 29, 1972Publication History Published online1 May 2002Published inissue 29 February...

10.1021/bi00755a003 article EN Biochemistry 1972-02-29

10.1016/0003-9861(71)90515-7 article EN Archives of Biochemistry and Biophysics 1971-02-01

10.1016/0003-9861(65)90043-3 article EN Archives of Biochemistry and Biophysics 1965-11-01

The role(s) of the novel stargazin-like gamma-subunit proteins remain controversial. We have shown previously that neuron-specific gamma7 suppresses expression certain calcium channels, particularly Ca(V)2.2, and is therefore unlikely to operate as a channel subunit. now show effect on Ca(V)2.2 via an increase in degradation rate mRNA hence reduction protein level. Furthermore, exogenous PC12 cells also decreased endogenous Conversely, knockdown with short-hairpin RNAs produced reciprocal...

10.1523/jneurosci.2709-08.2008 article EN cc-by-nc-sa Journal of Neuroscience 2008-10-15
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