A5043895812- Medication Adherence and Compliance
- Chronic Disease Management Strategies
- Pharmaceutical Practices and Patient Outcomes
- Opioid Use Disorder Treatment
- Child and Adolescent Health
- Diabetes Treatment and Management
- Diabetes Management and Research
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- Substance Abuse Treatment and Outcomes
- Pharmaceutical Economics and Policy
- Electronic Health Records Systems
- Pain Management and Opioid Use
- Data Quality and Management
- Diabetes Management and Education
- Child Abuse and Trauma
- Biomedical Text Mining and Ontologies
- Pharmaceutical studies and practices
- Nursing Diagnosis and Documentation
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare Systems and Technology
- Health disparities and outcomes
- Global Cancer Incidence and Screening
- Health Policy Implementation Science
Medical University of South Carolina
2016-2023
The University of Texas Health Science Center at Houston
2022
Janssen (United States)
2014-2016
Janssen Scientific Affairs (United States)
2016
Regenstrief Institute
2009-2015
Indiana University – Purdue University Indianapolis
2008-2012
Indiana University School of Medicine
2009-2012
Indiana University
2009
Abstract Objectives To evaluate the utility of applying Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) across multiple observational databases within an organization and to apply standardized analytics tools for conducting research. Materials methods Six deidentified patient-level datasets were transformed OMOP CDM. We evaluated extent information loss that occurred through standardization process. developed a analytic tool replicate cohort construction process...
Kidney Disease Improving Global Outcomes (KDIGO) 2013 updated the classification and risk stratification of chronic kidney disease (CKD) to include both level renal function urinary albumin excretion (UAE). The update subclassifies previous category moderate impairment. There is currently limited information on prevalence CKD based this new in United States (US) adults with type 2 diabetes mellitus (T2DM). objective study was provide such estimates, for T2DM overall those ≥ 65 years age. We...
Depression in people with diabetes can result increased risk for diabetes-related complications. The prevalence of depression has been estimated to be 17.6 % type 2 mellitus (T2DM), based on studies published between 1980 and 2005. There is a lack more recent estimates among the US general T2DM population.The present study used National Health Nutrition Examination Survey (NHANES) 2005-2012 data provide an updated, population-based estimate T2DM. NHANES cross-sectional survey nationally...
This project assessed performance of natural language processing (NLP) and machine learning (ML) algorithms for classification brain MRI radiology reports into acute ischemic stroke (AIS) non-AIS phenotypes.All from a single academic institution over two year period were randomly divided 2 groups ML: training (70%) testing (30%). Using "quanteda" NLP package, all text data parsed tokens to create the frequency matrix. Ten-fold cross-validation was applied bias correction set. Labeling AIS...
Social isolation is an important social determinant that impacts health outcomes and mortality among patients. The National Academy of Medicine recently recommended be documented in electronic records (EHR). However, usually not recorded or obtained as coded data but rather collected from patient self-report clinical narratives. This study explores the feasibility effectiveness natural language processing (NLP) strategy for identifying patients who are socially isolated We used Medical...
To incorporate value-based weight scaling into the Fellegi-Sunter (F-S) maximum likelihood linkage algorithm and evaluate performance of modified algorithm. Background Because healthcare data are fragmented across many systems, record is a key component fully functional health information exchanges. Probabilistic methods produce more accurate, dynamic, robust matching results than rule-based approaches, particularly when patient records that lack unique identifiers. Theoretically, relative...
A recent Canadian case-control study reported a 4.5-fold increased risk of retinal detachment (RD) during oral fluoroquinolone use. Of the fluoroquinolone-exposed cases, 83 % were exposed to ciprofloxacin. We sought replicate this finding, and assess whether it applied all fluoroquinolones.In two large US healthcare databases, we performed three analyses: one replicating study; addressing additional potential confounders; that sample size by dropping study's requirement for prior...
Background: Using the International Classification of Diseases (ICD) codes alone to record opioid use disorder (OUD) may not completely document OUD in electronic health (EHR). We developed and evaluated natural language processing (NLP) approaches identify from clinal note. explored concordance between ICD-coded NLP-identified OUD. Methods: studied EHRs 13,654 (female: 8223; male: 5431) adult non-cancer patients who received chronic therapy (COT) had at least one clinical note 2013 2018. Of...
Opioids can suppress gonadal hormone production, which may result in low testosterone levels. To date, there have been no large-scale population-based studies examining the extent to opioid use contribute changes Cross-sectional study. 2011–2012 National Health and Nutrition Examination Survey. Participants 17 years older who had data on prescription medication usage serum levels available. were divided two groups, exposed unexposed. Testosterone of participants responded that they (n = 320)...
Abstract Background Child abuse and neglect (CAN) is prevalent, associated with long-term adversities, often undetected. Primary care settings offer a unique opportunity to identify CAN facilitate referrals, when warranted. Electronic health records (EHR) contain extensive information support healthcare decisions, yet time constraints preclude most providers from thorough EHR reviews that could indicate CAN. Strategies summarize data convey this has potential mitigate CAN-related sequelae....
To understand weight loss strategies, changes, goals, and behaviors in people with type 2 diabetes mellitus (T2DM) whether these differ by ethnicity.T2DM was identified self-reported diagnosis using the NHANES 2005-2012 data, which also included measured current body height, prior year, aspired weight. Nineteen strategies were evaluated for association ≥5% or gain versus <5% change.Among T2DM, 88.0% overweight/obese (body mass index [BMI] ≥25 kg/m(2)) year 86.1% year. About 60% of took...
Abstract Opioid Overdose Network is an effort to generalize and adapt existing research data network, the Accrual Clinical Trials (ACT) Network, support design of trials for survivors opioid overdoses presenting emergency departments (ED). Four institutions (Medical University South Carolina [MUSC], Dartmouth Medical School [DMS], Kentucky [UK], California San Diego [UCSD]) worked ACT network. The approach that was taken enhance network focused on 4 activities: cloning extending...
Observational data are increasingly being used for pharmacoepidemiological, health services and clinical effectiveness research. Since pharmacies first introduced low-cost prescription programs (LCPP), researchers have worried that about the medications provided through these might not be available in observational derived from administrative sources, such as payer claims or pharmacy benefit management (PBM) company transactions.We Indiana Network Patient Care to estimate proportion of...
Following publication of the original article [1], authors reported an error in one authors' names.