A5101649115- Drug-Induced Hepatotoxicity and Protection
- Drug Transport and Resistance Mechanisms
- Pharmacological Effects of Natural Compounds
- Pharmacogenetics and Drug Metabolism
- Pharmacological Effects and Toxicity Studies
- Liver Disease Diagnosis and Treatment
- Bone health and treatments
- Liver Diseases and Immunity
- Plant Toxicity and Pharmacological Properties
Soonchunhyang University
2012-2015
Soonchunhyang University Hospital
2014
Accurate diagnosis of drug-induced liver injury (DILI) is difficult without considering the possibility underlying diseases, especially autoimmune hepatitis (AIH). We investigated clinical patterns in patients with a history medication, liver-function abnormalities, and whom biopsy was conducted, focusing on accompaniment by AIH.The clinical, serologic, histologic findings 29 were compared analyzed. The aged 46.2±12.8 years (mean±SD), 72.4% patient female. most common symptom causal drug...
Clinical Features of Drug-induced Liver Injury According to EtiologyDrug-induced liver injury (DILI) is an increasingly common cause acute hepatitis.We examined clinical features and types 65 affected patients who underwent biopsy according DILI etiology.The major causes were the use herbal medications (43.2%), prescribed (21.6%), traditional therapeutic preparations dietary supplements (35%).DILI from medications, preparations, was associated with higher elevations in aspartate...
Methimazole and prophylthiouracil are commonly prescribed for patients with hyperthyroidism. The serious side effect of toxic hepatitis caused by these two drugs is well known. According to recent Korean American management guidelines hyperthyroidism, mehimazole recommended as the first-choice antithyroid drug treatment Toxic rarely occurs in methimazole users. We report a rare case 52-year-old female after use that had past medical history simvastatin induced liver injury. Key words:...