A5042020251- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Inflammatory Biomarkers in Disease Prognosis
- Circular RNAs in diseases
- Diabetes Treatment and Management
- Extracellular vesicles in disease
- Functional Brain Connectivity Studies
- MicroRNA in disease regulation
- Cardiac pacing and defibrillation studies
- Cardiovascular Disease and Adiposity
- Dementia and Cognitive Impairment Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Birth, Development, and Health
- Parathyroid Disorders and Treatments
- Phytoestrogen effects and research
- Medication Adherence and Compliance
- Ultrasound Imaging and Elastography
- Body Composition Measurement Techniques
- Microwave Imaging and Scattering Analysis
Bucheon University
2018-2024
Soonchunhyang University
2012-2024
Yantaishan Hospital
2024
Ningxia Medical University
2024
Seoul National University Hospital
2021-2023
First Hospital of Jilin University
2023
Jilin University
2023
Gachon University
2022
Sejong General Hospital
2022
Inha University Hospital
2022
The number of people with heart failure (HF) is increasing worldwide, and the social burden as HF has high mortality morbidity. We aimed to provide updated trends on epidemiology in Korea shape future measures against HF.
We aimed to understand the association between stent length and clinical outcomes after percutaneous coronary intervention (PCI) using newer-generation drug-eluting stents (DES).We analysed 9,217 patients who underwent stenting for a single lesion from GRAND-DES registry, patient-level pooled registry including five Korean multicentre DES registries. The median follow-up duration was 730 days (interquartile range 708 752 days). A total of 8,035 were classified into short group (≤40 mm),...
Abstract Background Although more than one-third of the patients with acute heart failure (AHF) have diabetes mellitus (DM), it is unclear if DM has an adverse impact on clinical outcomes. This study compared outcomes in hospitalized for AHF stratified by and left ventricular ejection fraction (LVEF). Methods The Korean Acute Heart Failure registry prospectively enrolled followed 5625 from March 2011 to February 2019. primary endpoints were in-hospital overall all-cause mortality. We...
Accurate diagnosis of drug-induced liver injury (DILI) is difficult without considering the possibility underlying diseases, especially autoimmune hepatitis (AIH). We investigated clinical patterns in patients with a history medication, liver-function abnormalities, and whom biopsy was conducted, focusing on accompaniment by AIH.The clinical, serologic, histologic findings 29 were compared analyzed. The aged 46.2±12.8 years (mean±SD), 72.4% patient female. most common symptom causal drug...
Background Elevated serum transaminase or alkaline phosphatase (ALP) has been proposed as a novel prognosticator for ST-segment elevation myocardial infarction (STEMI). We evaluated the combined prognostic impact of elevated transaminases and ALP on admission in STEMI patients who underwent primary percutaneous coronary intervention (PCI). Methods A total 1176 with undergoing PCI were retrospectively enrolled from INTERSTELLAR registry. Hypoxic liver injury (HLI) was defined > twice upper...
For a better heart failure outcome, it is fundamental to improve the awareness of at general population level. We conducted this study identify current status in Korean population.This cross-sectional nationwide survey recruited total 1,032 participants aged 30 years or older, based on stratification systematic sampling method. A 23-item questionnaire was surveyed through telephone interviews.Although 80% had heard failure, 47% exactly defined what is. minority correctly recognized lifetime...
Abstract Background Several biomarkers have been proposed as independent predictors of poor outcomes in ST-segment elevation myocardial infarction (STEMI). We investigated whether adding information obtained from routine blood tests including hypoxic liver injury (HLI), dysglycemia, anemia, and high neutrophil to lymphocyte ratio (NLR) could improve the prognostic performance TIMI risk score for prediction 1-year mortality. Methods A total 1057 patients with STEMI undergoing primary...
Inki Moon, M.D., M.S., Min Gyu Kong, Young Sok Ji, Se Hyung Kim, Ph.D., Seong Kyu Park, Jon Suh, and Mi-Ae Jang, Ph.D.. Ann Lab Med 2023;43:145-52. https://doi.org/10.3343/alm.2023.43.2.145
Large-scale studies about epidemiologic characteristics of renal infarction (RI) are few. In this study, we aimed to analyze the incidence and prevalence RI with comorbidities in South Korean population.We investigated medical history entire adult population between 2013 2019 using National Health Insurance Service database (n = 51,849,591 2019). Diagnosis were confirmed International Classification Disease, Tenth Revision, Clinical Modification codes. Epidemiologic characteristics,...
Abstract Background Although vasospastic angina (VSA) is known to be caused by coronary artery spasm, no study has fully elucidated the exact underlying mechanism. Moreover, in order confirm VSA, patients should undergo invasive angiography with spasm provocation test. Herein, we investigated pathophysiology of VSA using peripheral blood-derived induced pluripotent stem cells (iPSCs) and developed an ex vivo diagnostic method for VSA. Methods results With 10 mL blood from generated iPSCs...
Abnormal myocardial metabolism is a common pathophysiological process underlying ischemic heart disease and failure (HF). Trimetazidine an antianginal agent with unique mechanism of action that regulates energy might have beneficial effect in preventing HF patients undergoing revascularization. We aimed to evaluate the potential benefit trimetazidine incident hospitalization for after Using data model, we identified without prior revascularization from 8 hospital databases Korea. To compare...
This study was performed to investigate the association between four BP measurements (systolic blood pressure [SBP], diastolic [DBP], mean arterial [MAP], and pulse [PP]) TOD parameters (left ventricular mass index [LVMI], E / e ′, estimated glomerular filtration rate [eGFR], obstructive coronary artery disease [CAD]). Data were obtained from a nation‐wide registry, composed of 652 patients (471 women, 58.4 ± 10.5 years) with suspected CAD who underwent elective invasive angiography (CAG). A...
Factors associated with low heart failure (HF) awareness have not been well-evaluated. This study was conducted to find out which demographic features would be HF in the general population of Korea.A telephone interview 1,032 adults (58 years and 50.6% were male) across country. Based on answer 15 questions about HF, we scored from 0 points (mean, 7.53±2.75; median, 8; interquartile range, 6-9). A score <8 defined as awareness, a ≥8 high awareness.A total 478 subjects (46.3%) had awareness....
Height declines with age, and its degree differs among individuals. Despite epidemiologic evidence for the inverse relationship between adult height cardiovascular disease (CVD) incidence, clinical significance of loss in CVD remains to be elucidated. Therefore, this study investigated association incidence.In total, 127,573 Korean participants were enrolled; their heights monitored from 2002 2011. The annual (cm/year) was difference first last measurements within observation period divided...
Heart failure (HF) is a leading cause of hospitalization and death worldwide. The Steady Movement with Innovating Leadership for Failure (SMILE HF) aims to evaluate the clinical characteristics, management, hospital course, long-term outcomes patients hospitalized acute HF in South Korea.
Objective: This study aims to investigate how changes in peripheral blood metabolites Alzheimer’s Disease (AD) patients affect the development of Pelvic Organ Prolapse (POP) using a multi-omics approach. We specifically explore interactions signaling pathways, gene expression, and protein-metabolite interactions, with focus on GZMA cysteine age-related diseases. Methods: utilized analysis, including metabolomics transcriptomics, evaluate perturbations their effect POP AD patients....
Although coronary artery occlusion can have a negative effect on the myocardium, chronic total (CTO) exhibits different clinical features from those of acute myocardial infarction (AMI). In this study, we identify differential associations exosomal miRNAs with CTO and AMI. Exosomes were isolated plasma obtained arteries patients undergoing percutaneous intervention to treat (n = 29) AMI 24), followed by small RNA sequencing, target gene predictions, functional enrichment analyses. Promising...
To implement the effective docking and optimization of a new community comprehensive management information system cardiocerebrovascular disease-related auxiliary for community-based platform intelligent chronic disease management. The cooperation team distinct division labors were enforced according to standard operating procedures. This mode patient-centered medical home(PCMH) could offer scientific management, promote rational classification two-way referral systems improve service...
Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by disease course heart failure (HF).Methods: evaluated 227 patients with HF in a multi-center retrospective cohort that included those left ventricular ejection fraction (LVEF) ≤ 40% undergoing ARNI treatment. The were divided into newly diagnosed treatment initiated within 6 months diagnosis (de novo group) and who or admitted for exacerbation more than prior initiation (prior group)....
Body fluid monitoring and management are essential to control dyspnea prevent re-hospitalization in patients with chronic heart failure (HF). There several methods estimate monitor patient's volume status, such as symptoms, signs, body weight, implantable devices. However, these might be difficult use for reasons that slow reflect water change, inaccurate specific patients' condition, or invasive. Bioelectrical impedance analysis (BIA) is a novel method HF, the value prognosis has been...
The contribution of sex and initial clinical presentation to the long-term outcomes in patients undergoing percutaneous coronary intervention (PCI) is still debated.Individual patient data from 5 Korean-multicenter drug-eluting stent (DES) registries (The GRAND-DES) were pooled. A total 17,286 completed 3-year follow-up (5216 women 12,070 men). median duration was 1125 days (interquartile range 1097-1140 days), primary endpoint cardiac death at 3 years.The indication for PCI stable angina...