A5075284632- Colorectal Cancer Screening and Detection
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Growth Hormone and Insulin-like Growth Factors
- Microscopic Colitis
- Cardiac Health and Mental Health
- Pituitary Gland Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Genetic factors in colorectal cancer
- Esophageal Cancer Research and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutritional Studies and Diet
- Antiplatelet Therapy and Cardiovascular Diseases
- Chromatin Remodeling and Cancer
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Teratomas and Epidermoid Cysts
Hanmi Pharmaceutical (South Korea)
2021-2025
Yonsei University
2019-2023
Catholic University of Korea
2023
Uijeongbu St. Mary's Hospital
2023
Bridge University
2021
Kyung Hee University
2021
University Research Co (United States)
2021
The number of people with heart failure (HF) is increasing worldwide, and the social burden as HF has high mortality morbidity. We aimed to provide updated trends on epidemiology in Korea shape future measures against HF.
Background and Objectives: Heart failure (HF) is a disease with high morbidity mortality.With ageing society increasing prevalence of risk factors HF, the HF expected to increase, as well.In this official report Korean Society Failure epidemiology in Korea presented.Methods: The data National Health Insurance big data, (KorHF) Acute (KorAHF) registries have been used.Results: In 2018, prevalence, incidence, mortality patients, due were 2,261, 579, 245, 10.4 per 100.000persons,...
Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic and independently affects the development cardiovascular (CV) disease. We investigated whether steatosis and/or fibrosis are associated with incident heart failure (iHF), hospitalized HF (hHF), mortality, CV death in both general population patients.We analyzed 778,739 individuals without 7445 patients pre-existing aged 40 to 80 years who underwent national health check-up from January 2009 December 2012. The...
Early-onset dementia (EOD, onset age < 65) and late-onset (LOD, ≥ exhibit distinct features. Understanding the risk factors for development mortality in EOD LOD respectively is crucial personalized care. While are known mortality, their impact on remains unclear. We aimed to investigate how hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, osteoporosis influence of LOD, respectively. Using Korean National Health Insurance Service (NHIS) database, we collected 546,709...
We conducted a nationwide validation study of diagnostic algorithms to identify cases inflammatory bowel disease (IBD) within the Korea National Health Insurance System (NHIS) database.Using NHIS dataset, we developed 44 combining International Classification Diseases (ICD)-10 codes, codes for Rare and Intractable (RID) registration claims data health care encounters, pharmaceutical prescriptions IBD-specific drugs. For each algorithm, compared case identification results from electronic...
Choosing effective devices (inhaled corticosteroid [ICS]-long-acting β2 agonist [LABA] combination inhalers) as maintenance treatment is critical for managing patients with asthma. We aimed to compare ICS/LABA efficacy, safety, and adherence across inhaler types components in newly diagnosed Utilizing South Korea's National Health Insurance Service data, we conducted a population-based cohort study involving aged 18–80 years, asthma who received therapy between January 2016 December 2020....
Introduction: We explored the long-term evolution of direct healthcare costs for inflammatory bowel diseases (IBD) using a population-level database in country with an escalating burden IBD.Methods: searched Korean National Health Insurance Claims, which covers more than 97% South population. An IBD diagnosis was defined as combination billing code Crohn's disease (CD: K50.xx) or ulcerative colitis (UC: K51.xx) and at least one claim IBD-specific drugs. Between 2006 2015, total 59,447...
Jae Myung Cha, Min Seob Kwak, Hyun-Soo Kim, Su Young Sohee Park, Geun U Jung Kuk Lee, Soo Jin Hun Hee Joo Sung and Won Ho for the Big Data Research Group of Korean Society Gastroenterology. Gut Liver 2020;14:338-46. https://doi.org/10.5009/gnl19108
Non-alcoholic fatty liver disease (NAFLD) is a well-known risk factor for cardiovascular (CV) (CVD) and mortality. However, whether the progression or regression of NAFLD can increase decrease heart failure (HF) mortality has not been fully evaluated. We investigated association between changes in hepatic steatosis risks incident HF (iHF), hospitalization (hHF), including CV- liver-related mortality.Using database from National Health Insurance Service Korea January 2009 to December 2012, we...
Abstract The association of bipolar disorder (BD) with the risk cardiometabolic diseases and premature death in Asians needs to be further determined. Relatively less attention has been paid heart failure (HF) among outcomes. We analyzed Korean National Health Insurance Service database (2002–2018) for this population-based, matched cohort study. hazards ischemic stroke, disease (IHD), hospitalization HF (hHF), composite diseases, all-cause mortality during follow-up were compared between...
Abstract Objective Thiazides are the first‐line treatment for hypertension, however, they have been associated with hospitalizations thiazide‐associated hyponatremia (TAH). The aim of this study was to evaluate risk TAH and other drug‐associated in a Korean population. Methods used big data from National Health Insurance Sharing Service 1,943,345 adults treated hypertension January 2014 December 2016. participants were divided into two groups based on use thiazides. Cox proportional hazard...
Abstract Background The impact of hypertrophic cardiomyopathy (HCM) on cardiovascular and obstetrical outcomes in pregnant women remains unclear, particularly Asian populations. This study aimed to evaluate the maternal Korean with HCM. Methods Using data from National Health Insurance Service database, we identified who gave birth via cesarean section or vaginal delivery after being diagnosed HCM between 2006 2019. Maternal were assessed based trimester pregnancy. Results included 122 158...
Acromegaly is a rare, slowly progressive disease. Its mechanism not fully understood, and epidemiological research on Korean patients with acromegaly scarce. The purpose of this study was to determine the incidence prevalence assess comorbidities survival benefits based treatment options.This nationwide population-based cohort conducted using data Health Insurance Review Assessment claims database evaluate newly diagnosed cases during 2013-2017.During 5-year period, 1,093 were acromegaly....
OBJECTIVE We investigated the long-term clinical efficacy of fenofibrate use with regard to mortality and cardiovascular outcomes in patients type 2 diabetes. RESEARCH DESIGN AND METHODS performed a population-based cohort study using data South Korean National Health Insurance Service from 2003 2014. Of 63,727 participants diabetes aged 40–79 years, 5,057 users only were compared nonusers and/or omega-3 fatty acid 1:1 propensity matching. The primary end point was composite myocardial...
The aim was to evaluate whether this gastric cancer-screening programme effective in reducing oesophageal cancer mortality.A population-based retrospective cohort study conducted using the Korean National Cancer Screening Programme (NCSP) database. comprised 16,969 patients who had been diagnosed 2007-2014. We analysed association between history of NSCP for and mortality.Compared with never-screened subjects, ever-screened subjects an overall HR mortality 0.647 (95% CI, 0.617-0.679)....
Abstract The association between ulcerative colitis (UC) and uterine cervical cancer is still unclear. To investigate risk in South Korean women with UC, we analyzed the National Health Insurance claims data. UC was defined using both ICD-10 codes UC-specific prescriptions. We incident cases of diagnosed 2006 2015. Age-matched without (control group) were randomly selected from general population (1:3 ratio). Hazard ratios calculated multivariate Cox proportional hazard regression, event as...
We evaluated the effectiveness of kaolin-impregnated hemostatic gauze use in preperitoneal pelvic packing (PPP) for patients with hemodynamic instability due to severe fractures.Between May 2014 and October 2018, 53 75 who underwent PPP induced by fracture were enrolled. Their medical records prospectively collected retrospectively analyzed. QuikClot combat (hydrophilic impregnated kaolin) general surgical tape used 21 patients, while was remaining 32 patients.As there differences...
Concentrations of toxic chemicals in mothers highly correlate with those their children; moreover, the levels are higher children than mothers. Non-persistent a short half-life including phthalate metabolites, bisphenol A (BPA), triclosan (TCS), and parabens metabolized excreted through urine. Therefore, we assessed urine concentrations BPA, TCS, parabens; correlated exposure levels; within-individual variability these infants. We collected 225 71 samples from 45 36 infants, respectively....
Background/Aims: Inflammatory bowel disease (IBD) is associated with the occurrence of venous thromboembolism (VTE).However, to date, there have been few studies on risk VTE in Asian IBD patients.We aimed estimate incidence patients and determine if related increased risk. Methods:We performed a population-based cohort study between 2004 2015 using Korean National Health Insurance data.IBD were defined by ICD-10 codes.Incidence rates calculated among age-and sex-matched controls.Hazard...
To determine whether inflammatory bowel disease (IBD) is associated with the risk of developing prostate cancer (PCa) through a population-based study. Male patients aged ≥40 years, diagnosed IBD from 2010 to 2013 and without were identified followed up 2019. A 1:4 matched cohort male was created, based on age, income level Charlson comorbidity index. Multivariate Cox regression analysis conducted evaluate association prescence PCa requiring definitive treatment within 1 year diagnosis. The...
Lipid lowering therapy is essential to reduce the risk of major cardiovascular events; however, limited evidence exists regarding use statin with ezetimibe as primary prevention strategy for middle-aged adults. We aimed investigate impact single pill combination on clinical outcomes in relatively healthy patients when compared monotherapy.